Nephro-Proteomics

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Research Leader(s)

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Alfonso Otero González

MD, PhD Nephrology
ALFONSO.OTERO.GONZALEZ@SERGAS.ES

OrcId

Predoctoral Researchers

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Elena Iglesias Lamas

MD Nephrology
elena.iglesias.lamas@sergas.es

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Juan José Bravo López

MD Nephrology
juan.jose.bravo.lopez@sergas.es

Resident Researchers

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Beatriz Ferreiro Álvarez

MD Nephrology
beatriz.ferreiro.alvarez@sergas.es

External Collaborators

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Hugo Miguel Baptista Carreira dos Santos

BChem, PhD Applied Chemistry

Universidad Nova de Lisboa (Portugal

  • Chronic kidney disease
  • Glomerulonephritis
  • Proteomics
  • Peritoneal dialysis
  • Ageing
  • – URINARY PROTEOMICS AND CHRONIC KIDNEY DISEASE. Contribution of urinary proteomics to the study of podocyte disease associated with ageing.
    – PROTEOMICS AND LIQUID RENAL BIOPSY. Comprehensive study of protein content in plasma, urine and tissue of patients with glomerular nephropathy
    – PROTEOMIC ANALYSIS OF DIALYSATE LIQUID IN PERITONEAL DIALYSIS. Vitamin D-Binding Protein (DBP) and Alfa2-HS Glycoprotein in peritoneal effluent (EP). Analysis of correlation with vascular calcification and insulin resistance in patients in peritoneal dialysis.
2014

2015

2016

2017

Scientific Papers

  • DaSilva I, Huerta A, Quintana L, Redondo B, Iglesias E, Draibe J, Praga M, Ballarin J, Diaz-Encarnacion M. Rituximab for Steroid-Dependent or Frequently Relapsing Idiopathic Nephrotic Syndrome in Adults: A Retrospective, Multicenter Study in Spain. BioDrugs. 2017 Jun;31(3):239-49. PMID: 28534103. IF2017: 3.824; Q1. https://www.ncbi.nlm.nih.gov/pubmed/28534103 +Pubmed +DOI
  • Pérez Melón C, Ferreiro Álvarez B, Iglesias Lamas E, Camba Caride MJ, Borrajo Prol MP, Novoa Fernández E. Enterococcus gallinarum and Chilaiditi syndrome in peritoneal dialysis. Nefrologia. Sociedad Espanola de Nefrología; 2017 Mar;37(2):213-4. PMID: 27707577. IF2017: 1.167; Q4. http://www.ncbi.nlm.nih.gov/pubmed/27707577 +Pubmed +DOI

Scientific Papers

  • Brück K, Jager KJ, Dounousi E, Kainz A, Nitsch D, Ärnlöv J, Rothenbacher D, Browne G, Capuano V, Ferraro PM, Ferrieres J, Gambaro G, Guessous I, Hallan S, Kastarinen M, Navis G, Otero Gonzalez A, Palmieri L, Romundstad S, Spoto B, Stengel B, Tomson C, Tripepi G, Völzke H, Wiecek A, Gansevoort R, Schöttker B, Wanner C, Vinhas J, Zoccali C, Van Biesen W, Stel VS, Wi?cek A, Gansevoort R, Schöttker B, Wanner C, Vinhas J, Zoccali C, Van Biesen W, Stel VS, European CKD Burden Consortium. Erratum: Methodology used in studies reporting chronic kidney disease prevalence: A systematic literature review (Nephrology Dialysis Transplantation (2015) 30:4 (iv6-iv16) DOI:10.1093/NDT/gfv131). Nephrol Dial Transplant. 2016 Apr;31(4):680. PMID: 26908763. http://www.ncbi.nlm.nih.gov/pubmed/26908763 +Pubmed +DOI
  • Brück K, Stel VS, Gambaro G, Hallan S, Völzke H, Ärnlöv J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Otero-González A, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ, European CKD Burden Consortium. CKD Prevalence Varies across the European General Population. J Am Soc Nephrol. 2016 Jul;27(7):2135-47. PMID: 26701975. IF2016: 8.966; D1. http://www.ncbi.nlm.nih.gov/pubmed/26701975 +Pubmed +DOI
  • Pérez Melón C, Borrajo Prol M, Iglesias E, Ferreiro B, Camba Caride M. Daptomycin in peritoneal dialysis, intraperitoneal or intravenous. Nefrologia. 2016 Jul;36(4):461-2. PMID: 26680497. IF2016: 1.183; Q4. http://www.ncbi.nlm.nih.gov/pubmed/26680497 +Pubmed +DOI

Scientific Papers

  • Brück K, Jager KJ, Dounousi E, Kainz A, Nitsch D, Ärnlöv J, Rothenbacher D, Browne G, Capuano V, Ferraro PM, Ferrieres J, Gambaro G, Guessous I, Hallan S, Kastarinen M, Navis G, Gonzalez AO, Palmieri L, Romundstad S, Spoto B, Stengel B, Tomson C, Tripepi G, Völzke H, Wi?cek A, Gansevoort R, Schöttker B, Wanner C, Vinhas J, Zoccali C, Van Biesen W, Stel VS, European CKD Burden Consortium. Methodology used in studies reporting chronic kidney disease prevalence: a systematic literature review. Nephrol Dial Transplant. 2015 Aug;30 Suppl 4:iv6-16. PMID: 26209739. IF2014: 3.577; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26209739 +Pubmed +DOI
  • Otero Gonzalez A, Prol MPB, Caride MJC, Nores JS, Novoa E, Melon CP, Macia P, Alves MT, Cid M, Osorio E, Coto E, Macias Nunez JF. Estimated glomerular filtration rate (eGFR), 25(OH) D3, chronic kidney disease (CKD), the MYH9 (myosin heavy chain 9) gene in old and very elderly people. Int Urol Nephrol. 2015 Aug;47(8):1403-8. PMID: 26152646. IF2014: 1.519; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26152646 +Pubmed +DOI

Scientific Papers

  • Araújo JE, Oliveira E, Otero-Glez A, Santos Nores J, Igrejas G, Lodeiro C, Capelo JL, Santos HM. A comprehensive factorial design study of variables affecting protein extraction from formalin-fixed kidney tissue samples. Talanta. 2014 Feb;119:90-7. PMID: 24401389. IF: 3.545; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24401389 +Pubmed +DOI
  • Oliveira E, Araújo JE, Gómez-Meire S, Lodeiro C, Perez-Melon C, Iglesias-Lamas E, Otero-Glez A, Capelo JL, Santos HM. Proteomics analysis of the peritoneal dialysate effluent reveals the presence of calcium-regulation proteins and acute inflammatory response. Clin Proteomics. 2014;11(1):17. PMID: 24742231. IF: N/A. http://www.ncbi.nlm.nih.gov/pubmed/24742231 +Pubmed +DOI

Code
PI15/01467
Title
Acción estratégica en Galicia para la poliquistosis renal: establecimiento de un registro gallego y diagnóstico genético como una
Funder
Instituto de Salud Carlos III
Type
Multicéntrico
Duration
2016 – 2018
PI
Miguel García González (External PI)
Cols.
A. Otero
Code
PI13/02031
Title
Función renal (FR) y marcadores de inflamación en relación con mortalidad, eventos cardiovasculares y deterioro de FR. Estudio de cohortes en población general adulta: EPIRCE II.
Funder
Instituto de Salud Carlos III
Type
Multicéntrico
Duration
2014 – 2016
PI
Pilar Gayoso Diz (External PI)
Cols.
A. Otero
Code
MoTHER HDx
PI
Alfonso Otero González
Title
Estudio multicéntrico, abierto, prospectivo, aleatorizado para explorar la morbimortalidad en pacientes dializados con hemodiálisis extendida en comparación con la hemodiafiltración en línea
Start date
2019
Sponsor
Sociedad Espanola de Nefrología
Code
DOPPS 6
PI
Alfonso Otero González
Title
Dialysis Outcomes and Practice Patterns Study
Start date
2016
Sponsor
Arbor Research Collaborative for Health
Code
ABC-TREAT
PI
Alfonso Otero González
Title
Estudio prospectivo aleatorizado multicéntrico para demostrar los beneficios de la HD sin acetato (con citrato)
Start date
2016
Sponsor
FUNDACION SENEFRO
Title
Las pruebas diagnósticas desde la perspectiva poblacional: epidemiología de la enfermedad renal crónica y la resistencia a la insulina
URL
https://www.educacion.gob.es/teseo/mostrarRef.do?ref=1072065
Author
Pilar Gayoso Diz
Supervisor
Alfonso Otero González
External supervisor(s)/co-supervisor(s)
Arturo Gonzalez Quintela y Francisco Gude Sampedro
University
Universidad Santiago de Compostela
Date
17/06/2013
Title
UTILIDAD TERAPEUTICA DE LA HEMOFILTRACION VENO-VENOSA CONTINUA Y DEPURACION DE CITOKINAS EN EL SINDROME DE DISTRES RESPIRATORIO DEL ADULTO “
Author
Carmen Casas Garcia
Supervisor
Alfonso Otero González
Co-Supervisor
Alfonso Otero González
External supervisor(s)/co-supervisor(s)
JR Gonzalez Juanatey
University
santiago de compostela
Date
15/06/2003