Inmunología (IN1)
Principales líneas de investigación
- Nanomedicina. Biocompatibilidad: toxicidad y respuesta inmune a nanopartículas
- Vacunas: Respuesta inmune a diferentes prototipos / Tuberculosis
- Generación de anticuerpos monoclonales con aplicaciones diversas
- Desarrollo de biosensores
- Bioinformática: Genómica y Transcriptómica
- Inmunoterapia / Enfermedades autoinmunitarias
- Modelización de la respuesta inmune
- Suministro de anticuerpos monoclonales específicos para identificación y marcaje selectivo de larvas de mejillón
Investigadores Responsables
Investigadores Senior
Investigadores Postdoctorales
Investigadores Predoctorales
Investigadores Colaboradores
Técnicos
Artículos Científicos
Maietta I, Aristegui PD, Alvarez IG, Atanes OR, Garcia Fontan EM, Bautista ST,Gonzalez-Fernandez A, Simon-Vazquez R. Sequential YAP1/FOSL1 silencing andepigenetic therapy to overcome stromal barriers in pancreatic cancer. Int JPharm. 2025 Nov 10;684:126155. doi: 10.1016/j.ijpharm.2025.126155. Epub 2025 Sep7. PubMed PMID: 40925515.
Artículos Científicos
Chin KL, Anibarro L, Chang ZY, Palasuberniam P, Mustapha ZA, Sarmiento ME,Acosta A. Impacts of MDR/XDR-TB on the global tuberculosis epidemic: Challengesand opportunities. Curr Res Microb Sci. 2024 Oct 19;7:100295. doi:10.1016/j.crmicr.2024.100295. eCollection 2024. PubMed PMID: 39512261; PubMedCentral PMCID: PMC11541417.
Eltijani A, Embregts CWE, Magadan S, Wang J, Brugman S, Boudinot P, WiegertjesGF, Forlenza M. Distinct distribution and responses of IgM+,IgT1+ and IgT2+ B cells in common carp. Front Immunol. 2024Nov 11;15:1490776. doi: 10.3389/fimmu.2024.1490776. eCollection 2024. PubMedPMID: 39588374; PubMed Central PMCID: PMC11586371.
Maietta I, Verísimo García J, González Fernández Á. Organoides ¿Nueva revolución en biomedicina? Investigación: cultura, ciencia y tecnología. 2024;31:8-18.
Enlace
Rodrigo T, Tabernero EMA, Anibarro L, Gullon JA, Medina JF, Millet JP,Garcia-Clemente MMA, Saez A, Cayla JA, Garcia-Garcia JMA; IntegratedTuberculosis, Non-Tuberculous Mycobacteria Research Programme Working GroupPII-TB MNT of SEPAR. Analysis of the Evolution of Tuberculosis in Men and Womenin Spain Between 2017 and 2022. Is There a Different Incidence Decline by Gender?Arch Bronconeumol. 2024 May;60(5):312-315. doi: 10.1016/j.arbres.2024.02.002.Epub 2024 Feb 13. No abstract available. English, Spanish. PubMed PMID: 38431460.
Sanchez-Montalva A, Caminero JA, Guna MR, Sanz TR, Rabunal R, Millet JP,Gullon-Blanco JA, Anibarro L, Perez-Mendoza G, Medina JF, Gonzalez-Galan V,Tabernero E; Writing committee of the Spanish MDR TB consortium (in alphabeticalorder); Annex. Members of the Spanish MDR TB consortium group. Executive summary:Clinical practice guidelines on the management of resistant tuberculosis of theSpanish Society of Pulmonology and Thoracic Surgery (SEPAR) and the SpanishSociety of Infectious Diseases and Clinical Microbiology (SEIMC). Enferm InfeccMicrobiol Clin (Engl Ed). 2024 Dec;42(10):588-596. doi:10.1016/j.eimce.2024.09.001. PubMed PMID: 39626979.
Sanchez-Montalva A, Caminero JA, Guna MR, Sanz TR, Rabunal R, Millet JP,Gullon-Blanco JA, Anibarro L, Perez-Mendoza G, Medina JF, Gonzalez-Galan V,Tabernero E; Writing committee of the Spanish MDR TB consortium. ExecutiveSummary: Clinical Practice Guidelines on the Management of Resistant Tuberculosisof the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) and theSpanish Society of Infectious Diseases and Clinical Microbiology (SEIMC). ArchBronconeumol. 2024 Dec;60(12):759-767. doi: 10.1016/j.arbres.2024.08.001. Epub2024 Dec 2. English, Spanish. PubMed PMID: 39764791.
Santin M, Trajman A, Goletti D, Anibarro L. Editorial: Addressing tuberculosisinfection: an essential step in the fight against tuberculosis. Front Med(Lausanne). 2024 Jun 7;11:1428677. doi: 10.3389/fmed.2024.1428677. eCollection2024. No abstract available. PubMed PMID: 38912341; PubMed Central PMCID:PMC11190313.
Artículos Científicos
Amaral S, Lozano-Fernandez T, Sabin J, Gallego A, da Silva Morais A, Reis RL,Gonzalez-Fernandez A, Pashkuleva I, Novoa-Carballal R. End-on PEGylation ofheparin: Effect on anticoagulant activity and complexation with protamine. Int JBiol Macromol. 2023 Sep 30;249:125957. doi: 10.1016/j.ijbiomac.2023.125957. Epub2023 Jul 26. PubMed PMID: 37499705.
Chin KL, Anibarro L, Sarmiento ME, Acosta A. Challenges and the Way forward inDiagnosis and Treatment of Tuberculosis Infection. Trop Med Infect Dis. 2023 Jan28;8(2):89. doi: 10.3390/tropicalmed8020089. PubMed PMID: 36828505; PubMedCentral PMCID: PMC9960903.
Diego-Gonzalez L, Alvarez-Vinas M, Simon-Vazquez R, Dominguez H, Torres MD,Florez-Fernandez N. Characterization of the Antiproliferative Activity ofSargassum muticum Low and High Molecular Weight PolysaccharideFractions. Mar Drugs. 2023 Dec 27;22(1):16. doi: 10.3390/md22010016. PubMed PMID:38248641; PubMed Central PMCID: PMC10817663.
First NJ, Parrish KM, Martinez-Perez A, Gonzalez-Fernandez A, Bharrhan S,Woolard M, McLachlan JB, Scott RS, Wang J, Gestal MC. Bordetella spp. blockeosinophil recruitment to suppress the generation of early mucosal protection.Cell Rep. 2023 Nov 28;42(11):113294. doi: 10.1016/j.celrep.2023.113294. Epub 2023Oct 25. PubMed PMID: 37883230.
Garcia-Sanchez M, Castro M, Faro J. B cell receptors and free antibodies havedifferent antigen-binding kinetics. Proc Natl Acad Sci U S A. 2023 Aug29;120(35):e2220669120. doi: 10.1073/pnas.2220669120. Epub 2023 Aug 24. PubMedPMID: 37616223; PubMed Central PMCID: PMC10469035.
Gonzalez-Ballesteros N, Maietta I, Rey-Mendez R, Rodriguez-Arguelles MC,Lastra-Valdor M, Cavazza A, Grimaldi M, Bigi F, Simon-Vazquez R. GoldNanoparticles Synthesized by an Aqueous Extract of Codium tomentosum asPotential Antitumoral Enhancers of Gemcitabine. Mar Drugs. 2023 Jan; 21(1): 20.doi: 10.3390/md21010020. PubMed PMID: 36662193; PubMed Central PMCID: PMC9865996.
Martinez-Perez A, Diego-Gonzalez L, Vilanova M, Correia A, Simon-Vazquez R,Gonzalez-Fernandez A. Immunization with nanovaccines containing mutated K-Raspeptides and imiquimod aggravates heterotopic pancreatic cancer induced in mice.Front Immunol. 2023 Apr 12;14:1153724. doi: 10.3389/fimmu.2023.1153724.eCollection 2023. PubMed PMID: 37122717; PubMed Central PMCID: PMC10130386.
Neagu, M.; Grisi, F.; Pulvirenti, A.; Simón-Vázquez, R.; García-González, C.A.; Boccia, A.C. Updated Aspects of Safety Regulations for Biomedical Applications of Aerogel Compounds—Compendia-Like Evaluation. Safety 2023, 9, 80. https://doi.org/10.3390/safety9040080
Perez-Recio S, Grijota-Camino MD, Anibarro L, Rabunal-Rey R, Sabria J,Gijon-Vidaurreta P, Pomar V, Garcia-Gasalla M, Dominguez-Castellano A, Trigo M,Santos MJ, Cebollero A, Rodriguez S, Moga E, Penas-Truque A, Martos C,Ruiz-Serrano MJ, Garcia-de-Cara EI, Alcaide F, Santin M. Reversions ofQuantiFERON-TB Gold Plus in tuberculosis contact investigation: A prospectivemulticentre cohort study. PLoS One. 2023 Aug 30;18(8):e0285917. doi:10.1371/journal.pone.0285917. eCollection 2023. PubMed PMID: 37647315; PubMedCentral PMCID: PMC10468083.
Libros / Capítulos de libros
Lara Diego-González, Rosana Simón-Vázquez. Chapter 13 – Immunomodulatory properties of algae. In: Herminia Dominguez, Leonel Pereira, Stefan Kraan (eds.). Woodhead Publishing Series in Food Science, Technology and Nutrition, Functional Ingredients from Algae for Foods and Nutraceuticals (Second Edition). Woodhead Publishing, 2023, Pages 593-615,ISBN 9780323988193
Artículos Científicos
Castro R, Magadan S, Jouneau L, Mhana V, Pham HP, Mariotti-Ferrandiz E, Six A,Huetz F, Boudinot P. Clonotypic IgH Response against Systemic Viral infection inPronephros and Spleen of a Teleost Fish. J Immunol. 2022 Jun 1;208(11):2573-2582.doi: 10.4049/jimmunol.2200088. Epub 2022 May 16. PubMed PMID: 35577368.
Diego-Gonzalez L, Fernandez-Carrera A, Igea A, Martinez-Perez A, Real OliveiraMECD, Gomes AC, Guerra C, Barbacid M, Gonzalez-Fernandez A, Simon-Vazquez R.Combined Inhibition of FOSL-1 and YAP Using siRNA-Lipoplexes Reduces the Growthof Pancreatic Tumor. Cancers (Basel). 2022 Jun 24;14(13):3102. doi:10.3390/cancers14133102. PubMed PMID: 35804874; PubMed Central PMCID: PMC9265026.
Dobrovolskaia MA, Afonin KA, González-Fernández Á. Editorial to “Journey into the immunological properties of engineered nanomaterials: There and back again”. Adv Drug Deliv Rev. 2022;181:114100. PMID: 34954314. DOI: 10.1016/j.addr.2021.114100. http://www.ncbi.nlm.nih.gov/pubmed/34954314
Enlace
Hidalgo T, Simon-Vazquez R, Gonzalez-Fernandez A, Horcajada P. Cracking theimmune fingerprint of metal-organic frameworks. Chem Sci. 2021 Nov5;13(4):934-944. doi: 10.1039/d1sc04112f. eCollection 2022 Jan 26. PubMed PMID:35211258; PubMed Central PMCID: PMC8790785.
Enlace
Igea A, Carvalheiro T, Malvar-Fernandez B, Martinez-Ramos S, Rafael-Vidal C,Niemantsverdriet E, Varade J, Fernandez-Carrera A, Jimenez N, McGarry T,Rodriguez-Trillo A, Veale D, Fearon U, Conde C, Pego-Reigosa JM,Gonzalez-Fernandez A, Reedquist KA, Radstake TRDJ, van der Helm-Van Mil A, GarciaS. Central Role of Semaphorin 3B in a Serum-Induced Arthritis Model and ReducedLevels in Patients With Rheumatoid Arthritis. Arthritis Rheumatol. 2022Jun;74(6):972-983. doi: 10.1002/art.42065. Epub 2022 Apr 13. PubMed PMID:35001548; PubMed Central PMCID: PMC9322571.
Enlace
Maietta I, Martinez-Perez A, Alvarez R, De Lera AR, Gonzalez-Fernandez A,Simon-Vazquez R. Synergistic Antitumoral Effect of Epigenetic Inhibitors andGemcitabine in Pancreatic Cancer Cells. Pharmaceuticals (Basel). 2022 Jul2;15(7):824. doi: 10.3390/ph15070824. PubMed PMID: 35890123; PubMed CentralPMCID: PMC9323654.
Martinez-Perez A, Estevez O, Gonzalez-Fernandez A. Contribution and Future ofHigh-Throughput Transcriptomics in Battling Tuberculosis. Front Microbiol. 2022Feb 24;13:835620. doi: 10.3389/fmicb.2022.835620. eCollection 2022. PubMed PMID:35283833; PubMed Central PMCID: PMC8908424.
Santin M, Perez-Recio S, Grijota MD, Anibarro L, Barcala JM, De Souza-GalvaoML, Gijon P, Luque R, Sanchez F; RIFAKiD team trial. Comparison of threeshort-course rifamycin-based regimens for the prevention of tuberculosis inpatients with end-stage kidney disease: Study protocol for a randomised clinicaltrial (RIFAKiD-TB trial). PLoS One. 2022 Oct 21;17(10):e0276387. doi:10.1371/journal.pone.0276387. eCollection 2022. PubMed PMID: 36269714; PubMedCentral PMCID: PMC9586383.
Simon-Vazquez R, Tsapis N, Lorscheider M, Rodriguez A, Calleja P, Mousnier L,de Miguel Villegas E, Gonzalez-Fernandez A, Fattal E. Improving dexamethasonedrug loading and efficacy in treating arthritis through a lipophilic prodrugentrapped into PLGA-PEG nanoparticles. Drug Deliv Transl Res. 2022May;12(5):1270-1284. doi: 10.1007/s13346-021-01112-3. Epub 2022 Jan 6. PubMedPMID: 34993924; PubMed Central PMCID: PMC8734546.
Enlace
Vazquez-Temprano N, Ursua-Diaz MI, Salgado-Barreira A, Vazquez-Gallardo R,Tunez Bastida V, Anibarro L; el Grupo de Trabajo de Prevencion y Control de laTuberculosis de Galicia. [Decline of Tuberculosis Rates and COVID-19 Pandemic.Fact or Fiction?]. Arch Bronconeumol. 2022 Mar;58(3):272-274. doi:10.1016/j.arbres.2021.05.014. Epub 2021 Jun 1. No abstract available. Spanish.PubMed PMID: 34092895; PubMed Central PMCID: PMC8168331.
Libros / Capítulos de libros
Álvarez-Vallina L., González-Fernández A., Hernández D., Kossida S., Magadán-Mompó S., Reche A., de los Toyos, J. R., Ybarra G. Immunotechnology and its applications. Ediuno. Ediciones de la Universidad de Oviedo; 2022. ISBN: 978-84-18324-44-4. https://publicaciones.uniovi.es/catalogo/publicaciones/visor/-/journal_content/56_INSTANCE_e5GF/1302902/8898059
Carrera M, Magadán S. Proteomics for Development of Food Allergy Vaccines. In: Thomas S (ed.). Vaccine Design Methods in Molecular Biology, vol 2410. New York, NY: Humana; 2022. p. 673–89. ISBN: 978-1-0716-1884-4. https://link.springer.com/10.1007/978-1-0716-1884-4_36
Enlace
Faro-Rivas, JM., Faro-Rivas E. A method to analyze models of the dynamics of Germinal Centers. En: Graca, L. (eds) T-Follicular Helper Cells. Methods and Protocols, New York, NY: Humana; 2022. p. 111–123. ISBN: 978-1071617359. https://link.springer.com/protocol/10.1007/978-1-0716-1736-6_10
Fernández-Carrera A., Peleteiro-Olmedo M., González-Fernández A. Sistema inmunitario e vacinas. 1st. ed. Vigo: Servizo de publicacións Universidade de Vigo; 2022. ISBN: 978-84-81589-35-1. https://dialnet.unirioja.es/servlet/libro?codigo=871170
Gonzalez-Fernandez A. Imuno Power.1st Ed. La esfera de los libros; 2022. ISBN: 978-84-1384-49-0. https://www.esferalibros.com/libros/inmuno-power/
Mendoza M, Magadán S. Immunoglobulins in Teleost. Principles of Fish Immunology 2022:229–51. https://doi.org/10.1007/978-3-030-85420-1_7
Artículos Científicos
Dornburg A, Ota T, Criscitiello MF, Salinas I, Sunyer JO, Magadán S, Boudinot P, Xu Z, Flajnik MF, Singer A, Gambón-Deza F, Hansen JD, Yoder JA. From IgZ to IgT: A Call for a Common Nomenclature for Immunoglobulin Heavy Chain Genes of Ray-Finned Fish. Zebrafish. 2021;18(6):343–5. PMID: 34935497. DOI: 10.1089/zeb.2021.0071. http://www.ncbi.nlm.nih.gov/pubmed/34935497
Enlace
Edholm E-S, Fenton CG, Mondot S, Paulssen RH, Lefranc M-P, Boudinot P, Magadan S. Profiling the T Cell Receptor Alpha/Delta Locus in Salmonids. Front Immunol. 2021;12:753960. PMID: 34733285. DOI: 10.3389/fimmu.2021.753960. http://www.ncbi.nlm.nih.gov/pubmed/34733285
Enlace
Faro J, Castro M. Affinity Selection in Germinal Centers: Cautionary Tales andNew Opportunities. Cells. 2021 Apr 28;10(5):1040. doi: 10.3390/cells10051040.PubMed PMID: 33924933; PubMed Central PMCID: PMC8145379.
Ferreira-Gonçalves T, Constantin C, Neagu M, Reis CP, Sabri F, Simón-Vázquez R. Safety and efficacy assessment of aerogels for biomedical applications. Biomed Pharmacother. 2021 Dec;144:112356. PMID: 34710839. DOI: 10.1016/j.biopha.2021.112356. http://www.ncbi.nlm.nih.gov/pubmed/34710839
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Ferreiro L, Ruano-Ravina A, Otero-Mallo R, Pou-Alvarez C, Riveiro-Blanco V,Casal A, Suarez-Antelo J, Toubes ME, Cruz-Ferro E, Rodriguez-Nunez N, Ursua-DiazMI, Lama A, Pineiro-Lamas M, Rabade C, Zamarron C, Gonzalez-Barcala FJ,Valino-Lopez P, Anibarro L, Taboada-Rodriguez JA, Valdes L. Recentepidemiological trends in extrapulmonary TB in Galicia, Spain. Int J Tuberc LungDis. 2021 May 1;25(5):373-381. doi: 10.5588/ijtld.20.0910. PubMed PMID: 33977905.
Gao G, Magadan S, Waldbieser GC, Youngblood RC, Wheeler PA, Scheffler BE, Thorgaard GH, Palti Y. A long reads-based de-novo assembly of the genome of the Arlee homozygous line reveals chromosomal rearrangements in rainbow trout. G3 (Bethesda). 2021;11(4) PMID: 33616628. DOI: 10.1093/g3journal/jkab052. http://www.ncbi.nlm.nih.gov/pubmed/33616628
Enlace
González-Ballesteros N, Diego-González L, Lastra-Valdor M, Grimaldi M, Cavazza A, Bigi F, Rodríguez-Argüelles MC, Simón-Vázquez R. Saccorhiza polyschides used to synthesize gold and silver nanoparticles with enhanced antiproliferative and immunostimulant activity. Mater Sci Eng C Mater Biol Appl. 2021 Apr;123:111960. PMID: 33812588. DOI: 10.1016/j.msec.2021.111960. http://www.ncbi.nlm.nih.gov/pubmed/33812588
Enlace
Magadan S, Mondot S, Palti Y, Gao G, Lefranc MP, Boudinot P. Genomic analysis of a second rainbow trout line (Arlee) leads to an extended description of the IGH VDJ gene repertoire. Dev Comp Immunol. 2021 May;118:103998. PMID: 33450314. DOI: 10.1016/j.dci.2021.103998. http://www.ncbi.nlm.nih.gov/pubmed/33450314
Enlace
Martínez-Pérez A, Igea A, Estévez O, Ferreira CM, Torrado E, Castro AG, Fernández C, Spetz A-L, Adam L, López González M, Singh M, Reljic R, González-Fernández Á. Changes in the Immune Phenotype and Gene Expression Profile Driven by a Novel Tuberculosis Nanovaccine: Short and Long-Term Post-immunization. Front Immunol. 2021;11:589863. PMID: 33584654. DOI: 10.3389/fimmu.2020.589863. http://www.ncbi.nlm.nih.gov/pubmed/33584654
Enlace
Oliveira IM, Gonçalves C, Oliveira EP, Simón-Vázquez R, da Silva Morais A, González-Fernández Á, Reis RL, Oliveira JM. PAMAM dendrimers functionalised with an anti-TNF ? antibody and chondroitin sulphate for treatment of rheumatoid arthritis. Mater Sci Eng C Mater Biol Appl. 2021 Feb;121:111845. PMID: 33579481. DOI: 10.1016/j.msec.2020.111845. http://www.ncbi.nlm.nih.gov/pubmed/33579481
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Perez-Recio S, Pallares N, Grijota-Camino MD, Sanchez-Montalva A, Barcia L,Campos-Gutierrez S, Pomar V, Rabunal-Rey R, Balcells ME, Gazel D, Montiel N,Vicente D, Goic-Barisic I, Schon T, Paues J, Marekovic I, Cacho-Calvo J, Barac A,Goletti D, Garcia-Gasalla M, Barcala JM, Tortola MT, Anibarro L, Suarez-Toste I,Moga E, Gude-Gonzalez MJ, Naves R, Karsligil T, Martin-Penaranda T, Stevanovic G,Trigo M, Rubio V, Karaoglan I, Bayram N, Alcaide F, Tebe C, Santin M; ESCMIDStudy Group for Mycobacterial Infections (ESGMYC) and the Mycobacteria StudyGroup (GEIM) of the Spanish Society of Clinical Microbiology and InfectiousDiseases (SEIMC). Identification of Recent Tuberculosis Exposure UsingQuantiFERON-TB Gold Plus, a Multicenter Study. Microbiol Spectr. 2021 Dec22;9(3):e0097221. doi: 10.1128/Spectrum.00972-21. Epub 2021 Nov 10. PubMed PMID:34756079; PubMed Central PMCID: PMC8579846.
Varadé J, Magadán S, González-Fernández Á. Human immunology and immunotherapy: main achievements and challenges. Cell Mol Immunol. Springer US; 2021 Apr;18(4):805–28. PMID: 32879472. DOI: 10.1038/s41423-020-00530-6. http://www.ncbi.nlm.nih.gov/pubmed/32879472
Enlace
Vieira S, da Silva Morais A, Garet E, Silva-Correia J, Reis RL, González-Fernández Á, Oliveira JM. Methacrylated Gellan Gum/Poly-l-lysine Polyelectrolyte Complex Beads for Cell-Based Therapies. ACS Biomater Sci Eng. 2021;7(10):4898–913. PMID: 34533303. DOI: 10.1021/acsbiomaterials.1c00486. http://www.ncbi.nlm.nih.gov/pubmed/34533303
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Libros / Capítulos de libros
Faro J, Faro E. A method to analyze models of the dynamics of GCS in T-follicular Helper Cells. Methods in molecular Biology Series. 2021.
Nelissen I, Haase A, Anguissola S, Rocks L, Jacobs A, Willems H, Riebeling C, Luch A, Piret J-P, Toussaint O, Trouiller B, Lacroix G, Gutleb AC, Contal S, Diabate S, Weiss C, Lozano-Fernández T, González-Fernández A, Dusinska M, Huk A, Stone V, Kanase N, Nocun M, Stepnik M, Meschini S, Ammendolia MG, Lewinski N, Riediker M, Venturini M, Benetti F, Topinka J, Brzicova T, Milani S, Radler J, Salvati A, Dawson KA. Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study. In: Weiss C, Diabaté S (eds.). Toxicology and biocompatibility of nanomaterials. MDPI; 2021. p. 69–88. ISBN: 978-3-0365-2738-3. https://www.mdpi.com/books/pdfview/book/4784
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Artículos Científicos
Biferi MG, Cohen-Tannoudji M, García-Silva A, Souto-Rodríguez O, Viéitez-González I, San-Millán-Tejado B, Fernández-Carrera A, Pérez-Márquez T, Teijeira-Bautista S, Barrera S, Domínguez V, Marais T, González-Fernández Á, Barkats M, Ortolano S. Systemic Treatment of Fabry Disease Using a Novel AAV9 Vector Expressing ?-Galactosidase A. Mol Ther Methods Clin Dev. 2020 Mar;20:1–17. PMID: 33335943. DOI: 10.1016/j.omtm.2020.10.016. http://www.ncbi.nlm.nih.gov/pubmed/33335943
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Diego-González L, Crecente-Campo J, Paul MJ, Singh M, Reljic R, Alonso MJ, González-Fernández Á, Simón-Vázquez R. Design of Polymeric Nanocapsules for Intranasal Vaccination against Mycobacterium Tuberculosis: Influence of the Polymeric Shell and Antigen Positioning. Pharmaceutics. 2020 May;12(6) PMID: 32481601. DOI: 10.3390/pharmaceutics12060489. http://www.ncbi.nlm.nih.gov/pubmed/32481601
Enlace
Estévez O, Anibarro L, Garet E, Martínez A, Pena A, Barcia L, Peleteiro M, González-Fernández Á. Multi-parameter flow cytometry immunophenotyping distinguishes different stages of tuberculosis infection. J Infect. 2020;81(1):57–71. PMID: 32330526. DOI: 10.1016/j.jinf.2020.03.064. http://www.ncbi.nlm.nih.gov/pubmed/32330526
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Estévez O, Anibarro L, Garet E, Pallares Á, Barcia L, Calviño L, Maueia C, Mussá T, Fdez-Riverola F, Glez-Peña D, Reboiro-Jato M, López-Fernández H, Fonseca NA, Reljic R, González-Fernández Á. An RNA-seq Based Machine Learning Approach Identifies Latent Tuberculosis Patients With an Active Tuberculosis Profile. Front Immunol. 2020;11:1470. PMID: 32760401. DOI: 10.3389/fimmu.2020.01470. http://www.ncbi.nlm.nih.gov/pubmed/32760401
Enlace
Estévez O, Anibarro L, Garet E, Pallares Á, Pena A, Villaverde C, Del Campo V, González-Fernández Á. Identification of candidate host serum and saliva biomarkers for a better diagnosis of active and latent tuberculosis infection. PLoS One. 2020;15(7):e0235859. PMID: 32687494. DOI: 10.1371/journal.pone.0235859. http://www.ncbi.nlm.nih.gov/pubmed/32687494
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González-Fernández Á, Bermúdez Silva FJ, López-Hoyos M, Cobaleda C, Montoliu L, Del Val M, Leech K. Non-animal-derived monoclonal antibodies are not ready to substitute current hybridoma technology. Nat Methods. 2020;17(11):1069–70. PMID: 33020658. DOI: 10.1038/s41592-020-00977-5. http://www.ncbi.nlm.nih.gov/pubmed/33020658
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Magadán S. Adaptive immune receptor repertoires, an overview of this exciting field. Immunol Lett. 2020;221:49–55. PMID: 32113899. DOI: 10.1016/j.imlet.2020.02.013. http://www.ncbi.nlm.nih.gov/pubmed/32113899
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Mateos J, Estévez O, González-Fernández Á, Anibarro L, Pallarés Á, Reljic R, Mussá T, Gomes-Maueia C, Nguilichane A, Gallardo JM, Medina I, Carrera M. Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. Sci Rep. 2020 Mar;10(1):3844. PMID: 32123229. DOI: 10.1038/s41598-020-60753-5. http://www.ncbi.nlm.nih.gov/pubmed/32123229
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Nelissen I, Haase A, Anguissola S, Rocks L, Jacobs A, Willems H, Riebeling C, Luch A, Piret J-P, Toussaint O, Trouiller B, Lacroix G, Gutleb AC, Contal S, Diabaté S, Weiss C, Lozano-Fernández T, González-Fernández Á, Dusinska M, Huk A, Stone V, Kanase N, Nocu? M, St?pnik M, Meschini S, Ammendolia MG, Lewinski N, Riediker M, Venturini M, Benetti F, Topinka J, Brzicova T, Milani S, Rädler J, Salvati A, Dawson KA. Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study. Nanomater (Basel, Switzerland). 2020 Jul;10(8) PMID: 32707981. DOI: 10.3390/nano10081430. http://www.ncbi.nlm.nih.gov/pubmed/32707981
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Simón-Vázquez R, Peleteiro M, González-Fernández Á. Polymeric nanostructure vaccines: applications and challenges. Expert Opin Drug Deliv. 2020;17(7):1007–23. PMID: 32476491. DOI: 10.1080/17425247.2020.1776259. http://www.ncbi.nlm.nih.gov/pubmed/32476491
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Torres MD, Flórez-Fernández N, Simón-Vázquez R, Giménez-Abián JF, Díaz JF, González-Fernández Á, Domínguez H. Fucoidans: The importance of processing on their anti-tumoral properties. Algal Res. 2020 Jan;45:101748. DOI: 10.1016/j.algal.2019.101748. https://linkinghub.elsevier.com/retrieve/pii/S2211926419307180
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Artículos Científicos
Batlle R, Andrés E, Gonzalez L, Llonch E, Igea A, Gutierrez-Prat N, Berenguer-Llergo A, Nebreda AR. Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38? through TGF-? and JNK signaling. Nat Commun. Springer US; 2019;10(1):3071. PMID: 31296856. DOI: 10.1038/s41467-019-10946-y. http://www.ncbi.nlm.nih.gov/pubmed/31296856
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Carnero-Gregorio M, Molares-Vila A, Corbalán-Rivas A, Villaverde-Taboada C, Rodríguez-Cerdeira C. Effect of VSL#3 Probiotic in a Patient with Glycogen Storage Disease Type Ia and Irritable Bowel Disease-like Disease. Probiotics Antimicrob Proteins. 2019 Feb;11(1):143–9. PMID: 29441457. DOI: 10.1007/s12602-017-9372-9. http://www.ncbi.nlm.nih.gov/pubmed/29441457
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Carrera M, González-Fernández Á, Magadán S, Mateos J, Pedrós L, Medina I, Gallardo JM. Molecular characterization of B-cell epitopes for the major fish allergen, parvalbumin, by shotgun proteomics, protein-based bioinformatics and IgE-reactive approaches. J Proteomics. 2019 May;200:123–33. PMID: 30974223. DOI: 10.1016/j.jprot.2019.04.005. http://www.ncbi.nlm.nih.gov/pubmed/30974223
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Crecente-Campo J, Guerra-Varela J, Peleteiro M, Gutiérrez-Lovera C, Fernández-Mariño I, Diéguez-Docampo A, González-Fernández Á, Sánchez L, Alonso MJ. The size and composition of polymeric nanocapsules dictate their interaction with macrophages and biodistribution in zebrafish. J Control Release. 2019;308:98–108. PMID: 31306677. DOI: 10.1016/j.jconrel.2019.07.011. http://www.ncbi.nlm.nih.gov/pubmed/31306677
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Díaz-Peña R, de Los Santos MJ, Lucia A, Castro-Santos P. Understanding the role of killer cell immunoglobulin-like receptors in pregnancy complications. J Assist Reprod Genet. Journal of Assisted Reproduction and Genetics; 2019 May;36(5):827–35. PMID: 30847698. DOI: 10.1007/s10815-019-01426-9. http://www.ncbi.nlm.nih.gov/pubmed/30847698
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Faro J, von Haeften B, Gardner R, Faro E. A Sensitivity Analysis Comparison of Three Models for the Dynamics of Germinal Centers. Front Immunol. 2019;10(AUG):2038. PMID: 31543878. DOI: 10.3389/fimmu.2019.02038. http://www.ncbi.nlm.nih.gov/pubmed/31543878
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González-Ballesteros N, Diego-González L, Lastra-Valdor M, Rodríguez-Argüelles MC, Grimaldi M, Cavazza A, Bigi F, Simón-Vázquez R. Immunostimulant and biocompatible gold and silver nanoparticles synthesized using the Ulva intestinalis L. aqueous extract. J Mater Chem B. 2019;7(30):4677–91. PMID: 31364682. DOI: 10.1039/c9tb00215d. http://www.ncbi.nlm.nih.gov/pubmed/31364682
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Lorscheider M, Tsapis N, Simón-Vázquez R, Guiblin N, Ghermani N, Reynaud F, Canioni R, Abreu S, Chaminade P, Fattal E. Nanoscale Lipophilic Prodrugs of Dexamethasone with Enhanced Pharmacokinetics. Mol Pharm. 2019;16(7):2999–3010. PMID: 31117740. DOI: 10.1021/acs.molpharmaceut.9b00237. http://www.ncbi.nlm.nih.gov/pubmed/31117740
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Lozano?Fernández T, Dobrovolskaia M, Camacho T, González?Fernández Á, Simón?Vázquez R. Interference of Metal Oxide Nanoparticles with Coagulation Cascade and Interaction with Blood Components. Part Part Syst Charact. 2019 Apr;36(4):1800547. DOI: 10.1002/ppsc.201800547. https://onlinelibrary.wiley.com/doi/abs/10.1002/ppsc.201800547
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Magadan S, Jouneau L, Boudinot P, Salinas I. Nasal Vaccination Drives Modifications of Nasal and Systemic Antibody Repertoires in Rainbow Trout. J Immunol. 2019;203(6):1480–92. PMID: 31413108. DOI: 10.4049/jimmunol.1900157. http://www.ncbi.nlm.nih.gov/pubmed/31413108
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Magadan S, Krasnov A, Hadi-Saljoqi S, Afanasyev S, Mondot S, Lallias D, Castro R, Salinas I, Sunyer O, Hansen J, Koop BF, Lefranc M-P, Boudinot P. Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires. Front Immunol. 2019;10(November):2541. PMID: 31798572. DOI: 10.3389/fimmu.2019.02541. http://www.ncbi.nlm.nih.gov/pubmed/31798572
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Mateos J, Estévez O, González-Fernández Á, Anibarro L, Pallarés Á, Reljic R, Gallardo JM, Medina I, Carrera M. High-resolution quantitative proteomics applied to the study of the specific protein signature in the sputum and saliva of active tuberculosis patients and their infected and uninfected contacts. J Proteomics. 2019 Mar;195:41–52. PMID: 30660769. DOI: 10.1016/j.jprot.2019.01.010. http://www.ncbi.nlm.nih.gov/pubmed/30660769
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Navelsaker S, Magadan S, Jouneau L, Quillet E, Olesen NJ, Munang’andu HM, Boudinot P, Evensen Ø. Sequential Immunization With Heterologous Viruses Does Not Result in Attrition of the B Cell Memory in Rainbow Trout. Front Immunol. 2019 Nov;10(November):2687. PMID: 31824488. DOI: 10.3389/fimmu.2019.02687. http://www.ncbi.nlm.nih.gov/pubmed/31824488
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Olivieri DN, Gambón-Deza F. Iterative Variable Gene Discovery from Whole Genome Sequencing with a Bootstrapped Multiresolution Algorithm. Comput Math Methods Med. 2019 Feb;2019:3780245. PMID: 30886642. DOI: 10.1155/2019/3780245. http://www.ncbi.nlm.nih.gov/pubmed/30886642
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Reljic R, González-Fernández Á. Editorial: Nanoparticle Vaccines Against Infectious Diseases. Front Immunol. 2019;10(November):2615. PMID: 31787982. DOI: 10.3389/fimmu.2019.02615. http://www.ncbi.nlm.nih.gov/pubmed/31787982
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Torres Palenzuela JM, González Vilas L, Bellas FM, Garet E, González-Fernández Á, Spyrakos E. Pseudo-nitzschia Blooms in a Coastal Upwelling System: Remote Sensing Detection, Toxicity and Environmental Variables. Water. 2019 Sep;11(9):1954. DOI: 10.3390/w11091954. https://www.mdpi.com/2073-4441/11/9/1954
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Vieira S, da Silva Morais A, Garet E, Silva-Correia J, Reis RL, González-Fernández Á, Miguel Oliveira J. Self-mineralizing Ca-enriched methacrylated gellan gum beads for bone tissue engineering. Acta Biomater. 2019 Jul;93:74–85. PMID: 30708066. DOI: 10.1016/j.actbio.2019.01.053. http://www.ncbi.nlm.nih.gov/pubmed/30708066
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Libros / Capítulos de libros
Castro-Santos P, Díaz-Peña R. Pharmacoepigenetics of Rheumatic Disorders. In: Cacabelos R (ed.). Pharmacoepigenetics. Elsevier; 2019. p. 587–96. ISBN: 978-0-12-813940-0. https://linkinghub.elsevier.com/retrieve/pii/B9780128139394000206
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López OC, Pérez Nieto T, Ferreiro López A, Garet E, González-Fernández Á, Torres Palenzuela JM. Capítulo 8. Análisis de la eficacia de los filtros de arcilla en la retención de contaminación fecal y comparativa de nuevos métodos para la detección de contaminantes. In: Riadigos-García MM, Torres-Palenzuela JM (eds.). BIOAUGA: Red Gallega de Biorremediación y Energía del Agua. Universidade de Vigo – Tórculo; 2019. p. 118–23. Deposito Legal: VG 314-2019. ISBN: 978-84-8158-816-3. https://dialnet.unirioja.es/servlet/articulo?codigo=7470899
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Magadán-Mompó S, González-Fernández Á. Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice. In: Steinitz M (ed.). Human Monoclonal Antibodies Methods and Protocols Series: Methods in Molecular Biology (vol1904). New York, NY: Humana Press. Springer New York; 2019. p. 253–91. ISBN: 978-1-4939-8957-7. ISBN: 978-1-4939-8957-7. https://www.springer.com/gp/book/9781493989577
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Artículos Científicos
Anibarro L, Cortés E, Chouza A, Parafita-Fernández A, García JC, Pena A, Fernández-Cid C, González-Fernández Á. Early treatment of tuberculous uveitis improves visual outcome: a 10-year cohort study. Infection. 2018 Aug;46(4):549–54. PMID: 29869018. DOI: 10.1007/s15010-018-1161-1. http://www.ncbi.nlm.nih.gov/pubmed/29869018
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Crecente-Campo J, Lorenzo-Abalde S, Mora A, Marzoa J, Csaba N, Blanco J, González-Fernández Á, Alonso MJ. Bilayer polymeric nanocapsules: A formulation approach for a thermostable and adjuvanted E. coli antigen vaccine. J Control Release. 2018 Jul;286:20–32. PMID: 30017722. DOI: 10.1016/j.jconrel.2018.07.018. http://www.ncbi.nlm.nih.gov/pubmed/30017722
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Dávila-Grana Á, Diego-González L, González-Fernández Á, Simón-Vázquez R. Synergistic Effect of Metal Oxide Nanoparticles on Cell Viability and Activation of MAP Kinases and NF?B. Int J Mol Sci. 2018 Jan;19(1):246. PMID: 29342925. DOI: 10.3390/ijms19010246. http://www.ncbi.nlm.nih.gov/pubmed/29342925
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Giménez-Marqués M, Bellido E, Berthelot T, Simón-Yarza T, Hidalgo T, Simón-Vázquez R, González-Fernández Á, Avila J, Asensio MC, Gref R, Couvreur P, Serre C, Horcajada P. GraftFast Surface Engineering to Improve MOF Nanoparticles Furtiveness. Small. 2018 Oct;14(40):e1801900. PMID: 30091524. DOI: 10.1002/smll.201801900. http://www.ncbi.nlm.nih.gov/pubmed/30091524
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González-Aramundiz JV, Peleteiro M, González-Fernández Á, Alonso MJ, Csaba NS. Protamine Nanocapsules for the Development of Thermostable Adjuvanted Nanovaccines. Mol Pharm. 2018;15(12):5653–64. PMID: 30375877. DOI: 10.1021/acs.molpharmaceut.8b00852. http://www.ncbi.nlm.nih.gov/pubmed/30375877
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Labastida-Conde RG, Ramírez-Pliego O, Peleteiro-Olmedo M, Lopez-Guerrero DV, Badillo-Godinez OD, Gutiérrez-Xicoténcatl M de L, Rosas-Salgado G, González-Fernández Á, Esquivel-Guadarrama FR, Santana MA. Flagellin is a Th1 polarizing factor for human CD4+ T cells and induces protection in a murine neonatal vaccination model of rotavirus infection. Vaccine. Elsevier Ltd; 2018 Jul;36(29):4188–97. PMID: 29891347. DOI: 10.1016/j.vaccine.2018.06.005. http://www.ncbi.nlm.nih.gov/pubmed/29891347
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Peleteiro M, Presas E, González-Aramundiz JV, Sánchez-Correa B, Simón-Vázquez R, Csaba N, Alonso MJ, González-Fernández Á. Polymeric Nanocapsules for Vaccine Delivery: Influence of the Polymeric Shell on the Interaction With the Immune System. Front Immunol. 2018 Apr;9(APR):791. PMID: 29725329. DOI: 10.3389/fimmu.2018.00791. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916973/pdf/fimmu-09-00791.pdf
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Rodrigues-Amorim D, Rivera-Baltanás T, Spuch C, Caruncho HJ, González-Fernandez Á, Olivares JM, Agís-Balboa RC. Cytokines dysregulation in schizophrenia: A systematic review of psychoneuroimmune relationship. Schizophr Res. 2018 Nov;197:19–33. PMID: 29239785. DOI: 10.1016/j.schres.2017.11.023. http://www.ncbi.nlm.nih.gov/pubmed/29239785
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Szebeni J, Simberg D, González-Fernández Á, Barenholz Y, Dobrovolskaia MA. Roadmap and strategy for overcoming infusion reactions to nanomedicines. Nat Nanotechnol. 2018;13(12):1100–8. PMID: 30348955. DOI: 10.1038/s41565-018-0273-1. http://www.ncbi.nlm.nih.gov/pubmed/30348955
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Libros / Capítulos de libros
González-Fernández Á. Capítulo 1. Historia de la Inmunogenética. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf
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González-Fernández Á. Capítulo 10. Inmunogenética de la alergia. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf
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González-Fernández Á. Capítulo 17. Historia de los anticuerpos monoclonales. In: Antón A (ed.). Inmunología Tumoral e Inmunoterapia del Cáncer. Amazing Books; 2018. ISBN: 978-84-17403-15-7. https://amazingbooks.es/inmunologia-tumoral-e-inmunoterapia-del-cancer%0A
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González-Fernández Á. Capítulo 3. Genes de los Anticuerpos. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf
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González-Fernández África; Corell-Almuzara Alfredo; Otero Manel Juan; Muñiz Diaz, Eduardo; Regueiro González-Barros, Jose R (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf
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González-Fernández, África. Capítulo 11. Vacunas. Inmunotecnología y sus aplicaciones. Ediuno. Ediciones de la Universidad de Oviedo; 2018. p. 33–46. ISBN: 978-84-16343-73-7. https://publicaciones.uniovi.es/catalogo/publicaciones/-/asset_publisher/pW5r/content/inmunotecnologia-y-sus-aplicaciones?redirect=%2Fcatalogo%2Fpublicaciones%0A
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Magadán-Mompó S. Capítulo 2. Inmunización y obtención de antisueros policlonales y de anticuerpos monoclonales. Inmunotecnología y sus aplicaciones. Ediuno. Ediciones de la Universidad de Oviedo; 2018. p. 33–46. ISBN: 978-84-16343-73-7. https://publicaciones.uniovi.es/catalogo/publicaciones/-/asset_publisher/pW5r/content/inmunotecnologia-y-sus-aplicaciones?redirect=%2Fcatalogo%2Fpublicaciones%0A
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Artículos Científicos
Faro J, Castro M, Molina-París C. A unifying mathematical framework for experimental TCR-pMHC kinetic constants. Sci Rep. Nature Publishing Group; 2017 Apr;7:46741. PMID: 28443634. DOI: 10.1038/srep46741. IF2017: 4.122; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28443634
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Fernandez-Carrera A, Vigo E, Regueiro-Rodríguez C, González-Fernández Á, Olivieri D, Aroeira LS. Sensitive and non-invasive method for the in vivo analysis of membrane permeability in small animals. Lab Invest. 2017 Sep;97(9):1114–20. PMID: 28737767. DOI: 10.1038/labinvest.2017.66. IF2017: 4.254; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28737767
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Gomez-Tourino I, Kamra Y, Baptista R, Lorenc A, Peakman M. T cell receptor ?-chains display abnormal shortening and repertoire sharing in type 1 diabetes. Nat Commun. Springer US; 2017;8(1):1792. PMID: 29176645. DOI: 10.1038/s41467-017-01925-2. http://dx.doi.org/10.1038/s41467-017-01925-2
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Hidalgo T, Cooper L, Gorman M, Lozano-Fernández T, Simón-Vázquez R, Mouchaham G, Marrot J, Guillou N, Serre C, Fertey P, González-Fernández Á, Devic T, Horcajada P. Crystal structure dependent in vitro antioxidant activity of biocompatible calcium gallate MOFs. J Mater Chem B. 2017 Apr;5(15):2813–22. DOI: 10.1039/C6TB03101C. IF2017: 4.776; Q1. http://xlink.rsc.org/?DOI=C6TB03101C
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Hidalgo T, Giménez-Marqués M, Bellido E, Avila J, Asensio MC, Salles F, Lozano M V, Guillevic M, Simón-Vázquez R, González-Fernández A, Serre C, Alonso MJ, Horcajada P. Chitosan-coated mesoporous MIL-100(Fe) nanoparticles as improved bio-compatible oral nanocarriers. Sci Rep. 2017 Mar;7:43099. PMID: 28256600. DOI: 10.1038/srep43099. IF2017: 4.122; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28256600
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Maceiras AR, Almeida SCP, Mariotti-Ferrandiz E, Chaara W, Jebbawi F, Six A, Hori S, Klatzmann D, Faro J, Graca L. T follicular helper and T follicular regulatory cells have different TCR specificity. Nat Commun. Nature Publishing Group; 2017 Apr;8:15067. PMID: 28429709. DOI: 10.1038/ncomms15067. IF2017: 12.353; D1. http://www.ncbi.nlm.nih.gov/pubmed/28429709
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Ruhwald M, Aggerbeck H, Gallardo RV, Hoff ST, Villate JI, Borregaard B, Martinez JA, Kromann I, Penas A, Anibarro LL, de Souza-Galvão ML, Sánchez F, Rodrigo-Pendás JÁ, Noguera-Julian A, Martínez-Lacasa X, Tuñez MV, Fernández VL, Millet JP, Moreno A, Cobos N, Miró JM, Roldan L, Orcau A, Andersen P, Caylá JA, TESEC Working Group. Safety and efficacy of the C-Tb skin test to diagnose Mycobacterium tuberculosis infection, compared with an interferon ? release assay and the tuberculin skin test: a phase 3, double-blind, randomised, controlled trial. Lancet Respir Med. 2017 Apr;5(4):259–68. PMID: 28159608. DOI: 10.1016/S2213-2600(16)30436-2. IF2017: 21.466; D1. http://www.ncbi.nlm.nih.gov/pubmed/28159608
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Artículos Científicos
Calvo-Iglesias J, Pérez-Estévez D, Lorenzo-Abalde S, Sánchez-Correa B, Quiroga MI, Fuentes JM, González-Fernández Á. Characterization of a Monoclonal Antibody Directed against Mytilus spp Larvae Reveals an Antigen Involved in Shell Biomineralization. PLoS One. 2016 Mar;11(3):e0152210. PMID: 27008638. DOI: 10.1371/journal.pone.0152210. IF2016: 2.806; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27008638
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Estevez O, Garet E, Olivieri D, Gambón-Deza F. Amphibians have immunoglobulins similar to ancestral IgD and IgA from Amniotes. Mol Immunol. 2016 Jan;69:52–61. PMID: 26675067. DOI: 10.1016/j.molimm.2015.11.005. FI2016: 3.236; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26675067
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García-García J-M, Rodrigo T, Casals M, Ruiz-Manzano J, Pascual-Pascual T, Caylà JA, Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis-PIITB (Luis Anibarro). Spanish Compliance With Guidelines for Prescribing Four Drugs in the Intensive Phase of Standard Tuberculosis Treatment. Arch Bronconeumol. 2016 May;52(5):262–8. PMID: 26826890. DOI: 10.1016/j.arbres.2015.11.007. IF2016: 2.979; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26826890
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Gullón JA, García-García JM, Villanueva MÁ, Álvarez-Navascues F, Rodrigo T, Casals M, Anibarro L, García-Clemente MM, Jiménez MÁ, Bustamante A, Penas A, Caminero JA, Caylà J, Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis (PII TB). Tuberculosis Costs in Spain and Related Factors. Arch Bronconeumol. 2016 Dec;52(12):583–9. PMID: 27323653. DOI: 10.1016/j.arbres.2016.05.002. IF2016: 2.979; Q2. http://www.ncbi.nlm.nih.gov/pubmed/27323653
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Martins JT, Santos SF, Bourbon AI, Pinheiro AC, González-Fernández Á, Pastrana LM, Cerqueira MA, Vicente AA. Lactoferrin-based nanoparticles as a vehicle for iron in food applications – Development and release profile. Food Res Int. 2016 Dec;90:16–24. PMID: 29195869. DOI: 10.1016/j.foodres.2016.10.027. IF2016: 3.086; Q1. http://www.ncbi.nlm.nih.gov/pubmed/29195869
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Olivieri DN, Garet E, Estevez O, Sánchez-Espinel C, Gambón-Deza F. Genomic structure and expression of immunoglobulins in Squamata. Mol Immunol. 2016 Apr;72:81–91. PMID: 26998711. DOI: 10.1016/j.molimm.2016.03.003. IF2016: 3.236; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26998711
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Rodrigo T, Casals M, Caminero JA, García-García JM, Jiménez-Fuentes MA, Medina JF, Millet JP, Ruiz-Manzano J, Caylá J, Working Group of the Integrated Programme of Tuberculosis Research. Factors Associated with Fatality during the Intensive Phase of Anti-Tuberculosis Treatment. Chotirmall SH (ed.). PLoS One. 2016 Aug;11(8):e0159925. PMID: 27487189. DOI: 10.1371/journal.pone.0159925. IF2016: 2.806; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27487189
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Santin M, García-García J-M, Domínguez J, Panel of experts from the Mycobacteria Study Group (GEIM) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Respiratory Diseases and Thoracic Surgery (SEPAR). Guidelines for the use of interferon-? release assays in the diagnosis of tuberculosis infection. Enferm Infecc Microbiol Clin. 2016 May;34(5):303.e1-13. PMID: 26917222. DOI: 10.1016/j.eimc.2015.11.022. IF2016: 1.714; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26917222
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Santin M, Garcia-Garcia J-M, Rigau D, Altet N, Anibarro L, Casas I, Diez N, Garcia-Gasalla M, Martinez-Lacasa X, Penas AA, Perez-Escolano E, Sanchez F, Dominguez J, García-García J-M, Rigau D, Altet N, Anibarro L, Casas I, Díez N, García-Gasalla M, Martínez-Lacasa X, Penas AA, Pérez-Escolano E, Sánchez F, Domínguez J, Grupo de expertos del Grupo de Estudio de Micobacterias (GEIM) de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y la Sociedad Española de Enfermedades Respiratorias y Cirugía torácica (SEPAR), Panel of experts from the Mycobacteria Study Group (GEIM) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Respiratory Diseases and Thoracic Surgery (SEPAR). Executive summary of the guidelines for the use of interferon-gamma release assays in the diagnosis of tuberculosis infection. Enferm Infecc Microbiol Clin. 2016 May;34(5):304–8. PMID: 26926262. DOI: 10.1016/j.eimc.2015.11.021. IF2016: 1.714; Q3. http://www.n
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Simón-Vázquez R, Lozano-Fernández T, Dávila-Grana A, González-Fernández Á. Analysis of the activation routes induced by different metal oxide nanoparticles on human lung epithelial cells. Futur Sci OA. 2016 Jun;2(2):fso.16.2. PMID: 28031965. DOI: 10.4155/fso.16.2. IF2016: N/A. http://www.ncbi.nlm.nih.gov/pubmed/28031965
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Simón-Vázquez R, Lozano-Fernández T, Dávila-Grana A, González-Fernández A. Metal oxide nanoparticles interact with immune cells and activate different cellular responses. Int J Nanomedicine. 2016;11:4657–68. PMID: 27695324. DOI: 10.2147/IJN.S110465. IF2016: 4.300; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27695324
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Libros / Capítulos de libros
França Á, Pelaz B, Moros M, Sánchez-Espinel C, Hernández A, Fernández-López C, Grazú V, Fuente JM de la, Pastoriza-Santos I, González-Fernández Á. Chapter 4: Sterilization Case Study 1: Effects of Different Sterilization Techniques on Gold Nanoparticles. In: Dobrovolskaia MA, McNeil SE (eds.). Handbook of Immunological Properties of Engineered Nanomaterials Volume 1: Key Considerations for Nanoparticle Characterization Prior to Immunotoxicity Studies. 2nd ed. World Scientific; 2016. p. 77–92. ISBN: 978-981-3140-43-1. http://www.worldscientific.com/doi/abs/10.1142/9789813140431_0004
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Lorenzo-Abalde S, González-Fernández Á. Chapter 10: Nanostructures and Allergy. In: Dobrovolskaia MA, McNeil SE (eds.). Handbook of Immunological Properties of Engineered Nanomaterials Volume 1: Key Considerations for Nanoparticle Characterization Prior to Immunotoxicity Studies. 2nd ed. World Scientific; 2016. p. 241–69. ISBN: 978-981-3140-43-1. http://www.worldscientific.com/doi/abs/10.1142/9789813140479_0010
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Lorenzo-Abalde S, Simón-Vázquez R, Olmedo MP, Lozano-Fernández T, Estévez-Martínez O, Fernández-Carrera A, González-Fernández Á. Evaluating the Interactions Between Proteins and Components of the Immune System with Polymer Nanoparticles. In: Vauthier C, Ponchel G (eds.). Polymer Nanoparticles for Nanomedicines A Guide for their Design, Preparation and Development. Cham: Springer International Publishing; 2016. p. 221–90. ISBN: 978-3-319-41419-5. https://rd.springer.com/content/pdf/bfm%3A978-3-319-41421-8%2F1.pdf
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Artículos Científicos
Bellido E, Hidalgo T, Lozano MV, Guillevic M, Simón-Vázquez R, Santander-Ortega MJ, González-Fernández Á, Serre C, Alonso MJ, Horcajada P. Heparin-engineered mesoporous iron metal-organic framework nanoparticles: toward stealth drug nanocarriers. Adv Healthc Mater. 2015 Jun;4(8):1246–57. PMID: 25771896. DOI: 10.1002/adhm.201400755. IF2015: 5.760; D1. http://www.ncbi.nlm.nih.gov/pubmed/25771896
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Canoa P, Simón-Vázquez R, Popplewell J, González-Fernández Á. A quantitative binding study of fibrinogen and human serum albumin to metal oxide nanoparticles by surface plasmon resonance. Biosens Bioelectron. Elsevier; 2015 Dec;74:376–83. PMID: 26162328. DOI: 10.1016/j.bios.2015.05.070. IF2015: 7.476; D1. http://www.ncbi.nlm.nih.gov/pubmed/26162328
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Cooper L, Hidalgo T, Gorman M, Lozano-Fernández T, Simón-Vázquez R, Olivier C, Guillou N, Serre C, Martineau C, Taulelle F, Damasceno-Borges D, Maurin G, González-Fernández Á, Horcajada P, Devic T. A biocompatible porous Mg-gallate metal-organic framework as an antioxidant carrier. Chem Commun (Camb). 2015 Apr;51(27):5848–51. PMID: 25720815. DOI: 10.1039/c5cc00745c. IF2015: 6.567; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25720815
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Correia A, Ferreirinha P, Botelho S, Belinha A, Leitão C, Caramalho Í, Teixeira L, González-Fernandéz Á, Appelberg R, Vilanova M. Predominant role of interferon-? in the host protective effect of CD8(+) T cells against Neospora caninum infection. Sci Rep. 2015 Oct;5:14913. PMID: 26449650. DOI: 10.1038/srep14913. IF2015: 5.228; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26449650
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Correia-Pinto JF, Peleteiro M, Csaba N, González-Fernández Á, Alonso MJ. Multi-enveloping of particulated antigens with biopolymers and immunostimulant polynucleotides. J Drug Deliv Sci Technol. 2015 Dec;30:424–34. DOI: 10.1016/j.jddst.2015.08.010. IF2015: 0.620; Q4. http://linkinghub.elsevier.com/retrieve/pii/S1773224715300095
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de Souza LR, Muehlmann LA, Matos LC, Simón-Vázquez R, Lacava ZGM, De-Paula AMB, Mosiniewicz-Szablewska E, Suchocki P, Morais PC, González-Fernández Á, Báo SN, Azevedo RB. Antitumor activity and systemic effects of PVM/MA-shelled selol nanocapsules in lung adenocarcinoma-bearing mice. Nanotechnology. 2015 Dec;26(50):505101. PMID: 26580675. DOI: 10.1088/0957-4484/26/50/505101. IF2015: 3.573; Q1. http://stacks.iop.org/0957-4484/26/i=50/a=505101?key=crossref.50288d41c986c430342c79d022041ca8
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Gómez-Touriño I, Simón-Vázquez R, Alonso-Lorenzo J, Arif S, Calviño-Sampedro C, González-Fernández Á, Pena-González E, Rodríguez J, Viñuela-Roldán J, Verdaguer J, Cordero OJ, Peakman M, Varela-Calvino R. Characterization of the autoimmune response against the nerve tissue S100? in patients with type 1 diabetes. Clin Exp Immunol. 2015 May;180(2):207–17. PMID: 25516468. DOI: 10.1111/cei.12572. IF2015: 3.148; Q2. http://www.ncbi.nlm.nih.gov/pubmed/25516468
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González-Aramundiz JV, Peleteiro-Olmedo M, González-Fernández Á, Alonso Fernández MJ, Csaba NS. Protamine-based nanoparticles as new antigen delivery systems. Eur J Pharm Biopharm. 2015 Nov;97(Pt A):51–9. PMID: 26455338. DOI: 10.1016/j.ejpb.2015.09.019. IF2015: 3.975; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26455338
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Martins JT, Ramos ÓL, Pinheiro AC, Bourbon AI, Silva HD, Rivera MC, Cerqueira MA, Pastrana L, Malcata FX, González-Fernández Á, Vicente AA. Edible Bio-Based Nanostructures: Delivery, Absorption and Potential Toxicity. Food Eng Rev. Springer US; 2015 Dec;7(4):491–513. DOI: 10.1007/s12393-015-9116-0. IF2015: 4.375; D1. http://link.springer.com/article/10.1007/s12393-015-9116-0/fulltext.html
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Oliveira ACN, Raemdonck K, Martens T, Rombouts K, Simón-Vázquez R, Botelho C, Lopes I, Lúcio M, González-Fernández Á, Real Oliveira MECD, Gomes AC, Braeckmans K. Stealth monoolein-based nanocarriers for delivery of siRNA to cancer cells. Acta Biomater. 2015 Oct;25:216–29. PMID: 26225736. DOI: 10.1016/j.actbio.2015.07.032. IF2015: 6.008; D1. http://www.ncbi.nlm.nih.gov/pubmed/26225736
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Olivieri DN, Gambón-Cerdá S, Gambón-Deza F. Evolution of V genes from the TRV loci of mammals. Immunogenetics. 2015 Jul;67(7):371–84. PMID: 26024913. DOI: 10.1007/s00251-015-0850-5. IF2015: 2.303; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26024913
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Olivieri DN, Gambón-Deza F. V genes in primates from whole genome sequencing data. Immunogenetics. 2015 Apr;67(4):211–28. PMID: 25721877. DOI: 10.1007/s00251-015-0830-9. IF2015: 2.303; Q3. http://www.ncbi.nlm.nih.gov/pubmed/25721877
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Pereira P, Pedrosa SS, Correia A, Lima CF, Peleteiro-Olmedo M, González-Fernández Á, Vilanova M, Gama FM. Biocompatibility of a self-assembled glycol chitosan nanogel. Toxicol In Vitro. 2015 Apr;29(3):638–46. PMID: 25482991. DOI: 10.1016/j.tiv.2014.11.004. IF2015: 3.338; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25482991
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Posada García C, Pena A, Anibarro L, Pardavila RM, De La Torre C, González-Fernández A. Erythema induratum of Bazin induced by tuberculin skin test. Int J Dermatol. 2015 Nov;54(11):1297–9. PMID: 24320214. DOI: 10.1111/ijd.12363. IF2015: 1.415; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24320214
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Sousa-Herves A, Sánchez Espinel C, Fahmi A, González-Fernández Á, Fernandez-Megia E. In situ nanofabrication of hybrid PEG-dendritic-inorganic nanoparticles and preliminary evaluation of their biocompatibility. Nanoscale. 2015 Mar;7(9):3933–40. PMID: 25530028. DOI: 10.1039/c4nr06155a. IF2015: 7.760; D1. http://www.ncbi.nlm.nih.gov/pubmed/25530028
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Artículos Científicos
Anibarro L, Pena A. Tuberculosis in patients with haematological malignancies. Mediterr J Hematol Infect Dis. 2014 Jan;6(1):e2014026. PMID: 24803999. DOI: 10.4084/MJHID.2014.026. N/A; N/A. http://www.ncbi.nlm.nih.gov/pubmed/24803999
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Cruz-Ferro E, Ursúa-Díaz MI, Taboada-Rodríguez JA, Hervada-Vidal X, Anibarro L, Túñez V, Galician Tuberculosis Prevention and Control Programme Working Group. In reply (Effect of smear-negative pulmonary tuberculosis on transmission). Int J Tuberc Lung Dis. 2014 Jun;18(6):752–3. PMID: 24903951. DOI: 10.5588/ijtld.14.0084-2. IF: 2.315; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24903951
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Cruz-Ferro E, Ursúa-Díaz MI, Taboada-Rodríguez JA, Hervada-Vidal X, Anibarro L, Túñez V. Epidemiology of tuberculosis in Galicia, Spain, 16 years after the launch of the Galician tuberculosis programme. Int J Tuberc Lung Dis. 2014 Feb;18(2):134–40. PMID: 24429303. DOI: 10.5588/ijtld.13.0419. IF: 2.315; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24429303
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de Souza LR, Muehlmann LA, Dos Santos MSC, Ganassin R, Simón-Vázquez R, Joanitti GA, Mosiniewicz-Szablewska E, Suchocki P, Morais PC, González-Fernández Á, Azevedo RB, Báo SN. PVM/MA-shelled selol nanocapsules promote cell cycle arrest in A549 lung adenocarcinoma cells. J Nanobiotechnology. 2014 Aug;12:32. PMID: 25149827. DOI: 10.1186/s12951-014-0032-x. IF: 4.115; Q1. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4422290&tool=pmcentrez&rendertype=abstract
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Llop J, Estrela-Lopis I, Ziolo RF, González A, Fleddermann J, Dorn M, Vallejo VG, Simon-Vazquez R, Donath E, Mao Z, Gao C, Moya SE. Uptake, Biological Fate, and Toxicity of Metal Oxide Nanoparticles. Part Part Syst Charact. WILEY-V C H VERLAG GMBH; 2014 Jan;31(1):24–35. DOI: 10.1002/ppsc.201300323. IF: 3.081; Q1. http://doi.wiley.com/10.1002/ppsc.201300323
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Lozano-Fernández T, Ballester-Antxordoki L, Pérez-Temprano N, Rojas E, Sanz D, Iglesias-Gaspar M, Moya S, González-Fernández Á, Rey M. Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4. Nanomedicine. 2014 Aug;10(6):1301–10. PMID: 24650882. DOI: 10.1016/j.nano.2014.03.007. IF: 6.155; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24650882
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Nuñez Fernández MJ, Fachal Bermúdez C, Duran Muñoz D, Figueroa López RM, Sopeña Pérez-Argüelles B, García García JC, Anibarro García L. IgG4-related disease and isolated thoracic aortic aneurysm. Vasa. 2014 Sep;43(5):385–9. PMID: 25147016. DOI: 10.1024/0301-1526/a000375. IF: 1.000; Q4. http://www.ncbi.nlm.nih.gov/pubmed/25147016
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Olivieri DN, von Haeften B, Sánchez-Espinel C, Faro J, Gambón-Deza F. Genomic V exons from whole genome shotgun data in reptiles. Immunogenetics. 2014 Aug;66(7–8):479–92. PMID: 24893587. DOI: 10.1007/s00251-014-0784-3. IF: 2.227; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24893587
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Simón-Vázquez R, Lozano-Fernández T, Peleteiro-Olmedo M, González-Fernández Á. Conformational changes in human plasma proteins induced by metal oxide nanoparticles. Colloids Surf B Biointerfaces. 2014 Jan;113:198–206. PMID: 24095988. DOI: 10.1016/j.colsurfb.2013.08.047. IF: 4.152; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24095988
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Vicente S, Peleteiro M, Gonzalez-Aramundiz J V, Díaz-Freitas B, Martínez-Pulgarín S, Neissa JI, Escribano JM, Sanchez A, González-Fernández A, Alonso MJ. Highly versatile immunostimulating nanocapsules for specific immune potentiation. Nanomedicine (Lond). 2014 Oct;9(15):2273–89. PMID: 24673264. DOI: 10.2217/nnm.14.10. IF: 5.413; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24673264
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Libros / Capítulos de libros
de Carlos Villamarín A, Faro Rivas JM, González-Fernández Á, Martínez-Zorzano VS, Megías-Pacheco M, Molist-García P, Morán-Martínez P, Pasantes-Ludeña JJ, Pombal Diego MÁ, Quesada-Rodríguez H. Manual de técnicas experimentais en bioloxía molecular e celular – Servizo de Publicacións – Universidade de Vigo. Faro Rivas JM (ed.). 1st ed. Vigo: Banda verde – Manuais; 2014. ISBN: 9788481586749. http://publicacions.uvigo.es/publicacions_gl/contenido/publicacions/publicacion_0326.html?__locale=en
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Mompó SM, González-Fernández Á. Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice. In: Steinitz M (ed.). Human Monoclonal Antibodies: Methods and Protocols (Colección: Methods in Molecular Biology). Totowa, NJ (USA): Humana Press; 2014. p. 245–76. http://www.ncbi.nlm.nih.gov/pubmed/24037845
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