Virología y Patogénesis (VIP)
Principales líneas de investigación
- Desarrollo de proyectos de investigación relacionados con la epidemiología, virología y la patogénesis de la infección por VIH para la identificación y estudio de la evolución de biomarcadores relacionados con la inflamación y las comorbilidades en cohortes de personas que viven con VIH con diferentes situaciones viro-inmunológicas, incluidos los controladores de élite.
- Estudios sobre el papel de las vesículas extracelulares y la mitocondria en la infección por VIH: impacto en la patogénesis de la infección.
- Estudios para la identificación de nuevos marcadores en la interacción inflamación y enfermedad cardiovascular en la infección por VIH y SARS-CoV-2/COVID19.
- Impacto del tratamiento antirretroviral (ART) en la viremia residual y en los niveles de activación/inflamación en la infección por VIH.
- Evaluación del impacto de los bajos niveles de viremia y blips en pacientes con tratamiento antirretroviral estable.
- Estudios observacionales sobre las características epidemiológicas, clínicas, tratamiento y medidas de prevención (PrEP) de la infección por VIH y otras infecciones de transmisión sexual en personas que viven con VIH.
- Epidemiología Molecular de la infección por VIH incluyendo estudios de prevalencia y caracterización de resistencias a fármacos.
- Estudios de resistencias a fármacos y co-infecciones virales en África Occidental.
- Coordinación Científica de la Cohorte COVID-19 del IIS Galicia Sur y desarrollo de proyectos de investigación relacionados con la virología y patogénesis de la infección por SARS-CoV-2.
- Creación y coordinación científica de la Cohorte COVID-19 del Instituto de Investigación Sanitaria Galicia Sur (COHVID-GS).
- Estudios de dinámica de la carga viral de SARS-CoV-2 y anticuerpos frente al virus y evolución de citoquinas durante la infección por SARS-CoV-2/COVID-19.
- Estudios de caracterización de la respuesta inmunológica durante la infección por SARS-CoV-2.
- Desarrollo de test diagnósticos para la infección por SARS-CoV-2.
- Caracterización de los casos de los síntomas a largo plazo tras la infección por SARS-CoV-2 (COVID persistente).
- Estudios para la identificación de nuevos marcadores en la interacción inflamación-enfermedad cardiovascular en la infección por VIH y SARS-CoV-2/COVID19.
Investigadores Responsables
Investigadores Postdoctorales
Investigadores Predoctorales
Investigadores Colaboradores
Técnicos
Colaboradores Externos
Artículos Científicos
Alonso-Dominguez J, Gonzalez-Novoa JA, Lopez-Lopez A, Martinez-Barros I,Perez-Gonzalez A, Leiro-Fernandez V, Aguayo-Arjona J, Teijeira S, Veiga C, PovedaE. Artificial intelligence-based identification of key risk factors for longCOVID from early clinical data. J Infect Public Health. 2026 Jan;19(1):103051.doi: 10.1016/j.jiph.2025.103051. Epub 2025 Nov 13. PubMed PMID: 41242093.
Lopez Lopez A, Alonso Dominguez J, Martinez Barros I, Perez Gonzalez A, OcampoA, Morano L, Calderon Cruz B, Martinez Lopez de Castro N, Bisbal Pardo O,Perez-Olmeda M, Sanchez-Villegas J, Asensi V, Montero-Alonso M, Rodriguez-RosadoMartinez-Echevarria R, Poveda E; CoRIS Cohort. Elevated Plasma GDF-15 Levels AreAssociated with Aging, Multimorbidity, and Tobacco Exposure in People with HIV.Infect Dis Ther. 2026 Mar;15(3):715-731. doi: 10.1007/s40121-026-01302-x. Epub2026 Jan 21. PubMed PMID: 41563586; PubMed Central PMCID: PMC12924802.
Lopez Lopez A, Perez Gonzalez A, Alonso Dominguez J, Ocampo A, Miralles C,Morano L, Aguayo Arjona J, Martinez Lopez de Castro N, Poveda E. High prevalenceof polypharmacy and nervous system medications in people with HIV: across-sectional analysis. Sci Rep. 2026 Jan 27;16(1):6413. doi:10.1038/s41598-026-36832-4. PubMed PMID: 41593305; PubMed Central PMCID:PMC12910090.
Artículos Científicos
Alonso Dominguez J, Martinez Barros I, Vieitez I, Peleteiro M, Calderon-CruzB, Gonzalez-Novoa JA, Perez Gonzalez A, Leiro Fernandez V, Lopez Lopez A, PovedaLopez E. SARS-CoV-2 Viral Load and Cytokine Dynamics Profile as Early Signaturesof Long COVID Condition in Hospitalized Individuals. Influenza Other RespirViruses. 2025 Jan;19(1):e70068. doi: 10.1111/irv.70068. PubMed PMID: 39800769;PubMed Central PMCID: PMC11725401.
Antoli A, Vargas-Parra G, Sierra-Fortuny A, Gomez-Vazquez JL, Rofes P, MunteE, Viana-Errasti J, Marin-Montes R, Lopez-Doriga A, Feliubadalo L, Del Valle J,Perez-Gonzalez A, Poveda E, Solanich X, Lazaro C. From Rare to Common: GeneticInsights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.J Clin Immunol. 2025 May 27;45(1):100. doi: 10.1007/s10875-025-01892-0. PubMedPMID: 40423910; PubMed Central PMCID: PMC12116960.
Davina-Nunez C, Perez-Castro S, Cabrera-Alvargonzalez JJ, Gonzalez-Alonso E,Silva-Bea S, Rodriguez-Perez M, Figueroa-Lamas MDP, Perez-Gonzalez A, Del CampoV, Rojas A, Mendoza J, Regueiro-Garcia B. Subgenomic RNA and LimitedCross-Reactive Neutralising Antibodies Point to Potential Improvements inSARS-CoV-2 Clinical Handling. Int J Mol Sci. 2025 Mar 24;26(7):2948. doi:10.3390/ijms26072948. PubMed PMID: 40243564; PubMed Central PMCID: PMC11988571.
Izquierdo R, Suarez-Garcia I, Gomez-Garcia T, Marco-Sanchez C, Puente-FerreiroJ, Moreno C, Diaz A, Cabello-Clotet N, Vinuesa D, Blanco JL, Melus E,Gomez-Ayerbe C, Olalla J, Riera M, Bernardino JI, de Lopez Bernaldo de Quiros JC,Moreno S, Jarrin I; CoRIS cohort [Eva Poveda, Alexandre Pérez, Jacobo Alonso, Inés Martínez]. Should we measure quality of life among peoplewith HIV? A multicentre survey of physicians’ opinions in Spain. HIV Med. 2025Feb;26(2):308-318. doi: 10.1111/hiv.13726. Epub 2024 Oct 25. PubMed PMID:39455423; PubMed Central PMCID: PMC11786618.
Enlace
Izquierdo R, Suarez-Garcia I, Marco-Sanchez C, Perez-Latorre L, Riera M, CanoJ, Vilades C, Reus S, Olalla J, Gonzalez-Ruano P, Orviz E, Diaz A, Moreno S,Jarrin I; CoRIS cohort [Eva Poveda, Alexandre Pérez, Jacobo Alonso, Inés Martínez]. Health-related quality of life in people with HIV from the multicentre CoRIS cohort in Spain: Associated factors and short-term changes over time. HIV Med. 2025 Apr;26(4):606-620. doi: 10.1111/hiv.13762. Epub 2025 Jan21. PubMed PMID: 39835516; PubMed Central PMCID: PMC11970345.
Enlace
Suarez-Garcia I, Alejos B, Moreno C, Martin Torres J, Masia M, Garcia-FraileLJ, Riera M, Dalmau D, Rodriguez-Rosado R, Muga R, Moreno S, Jarrin I; CoRIS cohort [Eva Poveda, Alexandre Pérez, Jacobo Alonso, Inés Martínez]. Long-term effectiveness and tolerability of dolutegravir/lamivudine intreatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks.J Antimicrob Chemother. 2025 Mar 3;80(3):682-691. doi: 10.1093/jac/dkae456.PubMed PMID: 39710424; PubMed Central PMCID: PMC11879157.
Enlace
Artículos Científicos
Berenguer J, Jarrin I, Bellon JM, Diez C, Jimenez-Sousa MA, Lopez JC,Pinto-Martinez A, Moreno S, Montes ML, Iribarren JA, Orviz E, Portilla J,Villarroya F, Domingo P, Resino S; CoRIS Cohort (Eva Poveda, Alexandre Pérez, Luis Morano). Mitochondrial Haplogroups and Weight Gain After Initiating ART in Patients With HIV. J Infect Dis. 2024 Aug16;230(2):421-425. doi: 10.1093/infdis/jiae168. PubMed PMID: 38557859.
Blanco-Perez J, Salgado-Barreira A, Blanco-Dorado S, Gonzalez Bello ME,Caldera Diaz AC, Perez-Gonzalez A, Pallares Sanmartin A, Fernandez Villar A,Gonzalez-Barcala FJ. Clinical usefulness of serum angiotensin converting enzymein silicosis. Pulmonology. 2024 Jul-Aug;30(4):370-377. doi:10.1016/j.pulmoe.2022.06.002. Epub 2022 Oct 22. PubMed PMID: 36280590.
Corona D, Perez-Valero I, Camacho A, Gutierrez Liarte A, Montero-Alonso M,Aleman MR, Ruiz-Seco P, Perez Gonzalez A, Riera M, Jarrin I, Rivero-Juarez A,Rivero A. Effectiveness and safety of bictegravir/emtricitabine/tenofoviralafenamide in HIV late presenters. Int J Antimicrob Agents. 2024Jan;63(1):107016. doi: 10.1016/j.ijantimicag.2023.107016. Epub 2023 Oct 26.PubMed PMID: 37890734.
Martínez, C., Teijeira, S., Domínguez, P., Campanioni, S., Busto, L., González-Nóvoa, J. A., Alonso, J., Poveda, E., San Millán, B., & Veiga, C. Correlating Histopathological Microscopic Images of Creutzfeldt–Jakob Disease with Clinical Typology Using Graph Theory and Artificial Intelligence. Machine Learning and Knowledge Extraction. 2024;6(3):2018-32.
Moreno C, Izquierdo R, Alejos B, Hernando V, Perez de la Camara S, Peraire J, Macias J, Bernal E, Albendin-Iglesias H, Alcaraz B, Suarez-Garcia I, Moreno S, Jarrin I; CoRIS cohort [Eva Poveda, Alexandre Pérez, Jacobo Alonso, Inés Martínez]. Acceptability of Long-Acting Injectable Antiretroviral Treatment for HIV Management: Perspectives of Patients and Physicians in Spain. AIDS Patient Care STDS. 2024 Jul;38(7):305-314. doi: 10.1089/apc.2024.0093. Epub2024 Jun 25. PubMed PMID: 38916077.
Pantazis N, Sabin CA, Grabar S, Van der Valk M, Jarrin I, van Sighem A, MeyerL, Carlander C, Gill J, Volny Anne A, Spire B, Tariq S, Burns F, Costagliola D,Ruiz-Burga E, Touloumi G, Porter K; CASCADE Collaboration [Eva Poveda]. Changes in bodyweightafter initiating antiretroviral therapy close to HIV-1 seroconversion: aninternational cohort collaboration. Lancet HIV. 2024 Oct;11(10):e660-e669. doi:10.1016/S2352-3018(24)00183-8. Epub 2024 Aug 23. PubMed PMID: 39186940.
Perez-Gonzalez A, Rodriguez-Rivero S, Fernandez-Veiga P, Flores E, Poveda E,Gonzalez-Carrero J, Perez-Castro S, Labajo-Leal L, Miralles C, Ocampo A. AnalDysplasia Screening in People Living with HIV: Long-Term Follow-Up in a LargeCohort from Northwest Spain. AIDS Patient Care STDS. 2024 Jan;38(1):5-13. doi:10.1089/apc.2023.0231. Epub 2023 Dec 20. PubMed PMID: 38117576; PubMed CentralPMCID: PMC10794828.
Perez-Rodriguez MT, Lima O, Garrido M, Rincon A, Martinez-Lamas L,Perez-Gonzalez A, Araujo A, Amoedo A, Sousa A, Lopez A, Cabrera X, Rubianes M.The role of time to positive blood cultures in enhancing the predictivecapability of DENOVA score for diagnosing infective endocarditis in patients withEnterococcus faecalis bacteremia. Eur J Clin Microbiol Infect Dis. 2024Jul;43(7):1481-1486. doi: 10.1007/s10096-024-04843-6. Epub 2024 May 20. PubMedPMID: 38763988.
Poveda E, Fitzgerald W, Alonso-Dominguez J, Aguayo-Arjona J, Marino A, AlvarezH, Valcarce N, Perez A, Ruiz-Mateos E, Margolis L, Lederman MM, Freeman ML.Elevated plasma levels of IP-10 and MIG are early predictors of loss of controlamong elite HIV controllers. Front Immunol. 2024 Aug 29;15:1446730. doi:10.3389/fimmu.2024.1446730. eCollection 2024. PubMed PMID: 39267749; PubMedCentral PMCID: PMC11390527.
Romero-Ventosa EY, Garcia-Beloso N, Lopez-Lopez A, Martinez-Lopez-de-Castro N.Effectiveness and safety of pembrolizumab as first-line treatment for non-smallcell lung cancer in real clinical practice. J Oncol Pharm Pract. 2024 Jul23:10781552241264179. doi: 10.1177/10781552241264179. Online ahead of print.PubMed PMID: 39042931.
Artículos Científicos
Alonso-Dominguez J, Gallego-Rodriguez M, Martinez-Barros I, Calderon-Cruz B,Leiro-Fernandez V, Perez-Gonzalez A, Poveda E. High Levels of IL-1beta, TNF-alpha andMIP-1alpha One Month after the Onset of the Acute SARS-CoV-2 Infection, Predictors ofPost COVID-19 in Hospitalized Patients. Microorganisms. 2023 Sep 26;11(10):2396.doi: 10.3390/microorganisms11102396. PubMed PMID: 37894054; PubMed Central PMCID:PMC10609568.
Alvarez H, Gutierrez-Valencia A, Marino A, Saborido-Alconchel A, Calderon-CruzB, Perez-Gonzalez A, Alonso-Dominguez J, Martinez-Barros I, Gallego-Rodriguez M,Moreno S, Aldamiz T, Montero-Alonso M, Bernal E, Galera C, Llibre JM, Poveda E.IP-10 and MIG are sensitive markers of early virological response to HIV-1integrase inhibitors. Front Immunol. 2023 Oct 18;14:1257725. doi:10.3389/fimmu.2023.1257725. eCollection 2023. PubMed PMID: 37920466; PubMedCentral PMCID: PMC10619723.
Alvarez H, Mocroft A, Ryom L, Neesgaard B, Edwards S, Svedhem V, Gunthard HF,Zangerle R, Smith C, Castagna A, d’Arminio Monforte A, Wit F, Stecher M, LehmanC, Mussini C, Fontas E, Gonzalez E, Wasmuth JC, Sonnerborg A, De Wit S,Chkhartishvili N, Stephan C, Petoumenos K, Jaschinski N, Vannappagari V, GallantJ, Young L, Volny Anne A, Greenberg L, Martin-Iguacel R, Poveda E, Llibre JM;RESPOND (International Cohort Consortium of Infectious Diseases) Study Group.Plasma Human Immunodeficiency Virus 1 RNA and CD4+ T-Cell Counts Are Determinantsof Virological Nonsuppression Outcomes With Initial Integrase Inhibitor-BasedRegimens: A Prospective RESPOND Cohort Study. Clin Infect Dis. 2023 Aug22;77(4):593-605. doi: 10.1093/cid/ciad219. PubMed PMID: 37052343; PubMed CentralPMCID: PMC10893964.
Corredoira J, Miguez E, Mateo LM, Fernandez-Rodriguez R, Garcia-Rodriguez JF,Perez-Gonzalez A, Sanjurjo A, Pulian MV, Ayuso-Garcia B; In behalf all members ofGESBOGA group. The interaction between liver cirrhosis, infection byStreptococcus bovis, and colon cancer. Eur J Clin Microbiol Infect Dis. 2023Jul;42(7):907-912. doi: 10.1007/s10096-023-04618-5. Epub 2023 May 5. PubMed PMID:37145237.
Lopez-Lopez A, Gayoso-Rey M, Garcia-Beloso N, Romero-Ventosa Y, Robles-TorresD, Martinez-Reglero C, Pineiro-Corrales G. Real-world evidence of sorafenib forthe treatment of hepatocellular carcinoma: A single-center study. J Cancer ResTher. 2023 Jul-Sep;19(5):1345-1349. doi: 10.4103/jcrt.jcrt_308_21. PubMed PMID:37787306.
Martinez-Sanz J, Diaz-Alvarez J, Rosas M, Ron R, Iribarren JA, Bernal E,Gutierrez F, Ruiz Sancho A, Cabello N, Olalla J, Moreno S, Serrano-Villar S;CoRIS [Eva Poveda, Alexandre Pérez, Luis Morano, Celia Miralles, Antonio Ocampo, Guillermo Pousada, Lucía Patiño]. Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratioin predicting non-AIDS events. EBioMedicine. 2023 Sep;95:104773. doi:10.1016/j.ebiom.2023.104773. Epub 2023 Aug 26. PubMed PMID: 37639938; PubMedCentral PMCID: PMC10474064.
Nunez-Fernandez M, Ramos-Hernandez C, Garcia-Rio F, Perez-Gonzalez A,Tilve-Gomez A, Rodriguez-Fernandez P, Nodar-Germinas A, Fernandez-Garcia A,Ruano-Ravina A, Fernandez-Villar A. Evolution and long?term respiratory sequelaeafter severe COVID-19 pneumonia: nitric oxide diffusion measurement value. RespirRes. 2023 Feb 13;24(1):48. doi: 10.1186/s12931-023-02344-2. PubMed PMID:36782191; PubMed Central PMCID: PMC9924196.
Perez-Gonzalez A, Carballo R, Araujo-Ameijeiras A, Abad R, Navarro C, OcampoA, Poveda E, Potel C. Meningococcal carriage in men who have sex with menpresenting at a sexual health unit in Spain. Eur J Clin Microbiol Infect Dis.2023 Mar;42(3):287-296. doi: 10.1007/s10096-023-04550-8. Epub 2023 Jan 24. PubMedPMID: 36692604.
Poveda E, Fitzgerald W, Reglero C, Perez-Gonzalez A, Marino A, Alvarez H,Valcarce N, Llibre JM, Guillen SM, Munoz Fernandez MA, Ruiz-Mateos E, Margolis L,Lederman MM, Freeman ML. Interleukin 18 (IL-18) and IL-3 in ExtracellularVesicles: Biomarkers for Durable Elite Control of HIV-1. J Infect Dis. 2023 Jun15;227(12):1381-1385. doi: 10.1093/infdis/jiad042. PubMed PMID: 36790818; PubMedCentral PMCID: PMC10266942.
Sousa, Adrián MD?,†; Lima, Olalla MD?,†; Pérez-González, Alexandre MD?,‡; Araujo, Alejandro MD†; Longueira, Rebeca MD?,†; Otero, Antón MD?; Núñez, Marta MD§; Ramos, Cristina MD§; Martínez-Lamas, Lucía MD?; Crespo-Casal, Manuel MD?; Rubianes, Martin MD?; Pérez-Rodríguez, María Teresa MD?,†. Impact of Methylprednisolone Pulse on the Mortality of Patients With Acute Respiratory Distress Syndrome Secondary to COVID-19. Infectious Diseases in Clinical Practice 31(6):e1296, November 2023. | DOI: 10.1097/IPC.0000000000001296
Suarez-Garcia I, Alejos B, Hernando V, Vinuela L, Vera Garcia M, Rial-CresteloD, Perez Elias MJ, Albendin Iglesias H, Peraire J, Tiraboschi J, Diaz A, MorenoS, Jarrin I; Cohort of the Spanish HIV/AIDS Research Network (CoRIS) [Eva Poveda, Alexandre Pérez, Luis Morano, Celia Miralles, Antonio Ocampo, Guillermo Pousada, Lucía Patiño].Effectiveness and tolerability of dolutegravir/lamivudine for the treatment ofHIV-1 infection in clinical practice. J Antimicrob Chemother. 2023 Jun1;78(6):1423-1432. doi: 10.1093/jac/dkad102. PubMed PMID: 37099559; PubMedCentral PMCID: PMC10232237.
Vizcarra P, Moreno A, Vivancos MJ, Muriel Garcia A, Ramirez Schacke M,Gonzalez-Garcia J, Curran A, Palacios R, Sanchez Guirao AJ, Reus Banuls S, MorenoGuillen S, Casado JL; Spanish HIV Research Network (CoRIS) [Eva Poveda-López]. A Risk AssessmentTool for Predicting Fragility Fractures in People with HIV: Derivation andInternal Validation of the FRESIA Model. J Bone Miner Res. 2023Oct;38(10):1443-1452. doi: 10.1002/jbmr.4894. Epub 2023 Aug 23. PubMed PMID:37545089.
Artículos Científicos
Alvarez H, Rava M, Martinez C, Portilla J, Peraire J, Rivero A, Cervero M,Marino A, Poveda E, Llibre JM; CoRIS Study Group (Alexandre Pérez, Manuel Crespo, Luis Morano, Celia Miralles, Antonio Ocampo, Guillermo Pousada). Predictors of low-level HIVviraemia and virological failure in the era of integrase inhibitors: A Spanishnationwide cohort. HIV Med. 2022 Sep;23(8):825-836. doi: 10.1111/hiv.13265. Epub2022 Mar 1. PubMed PMID: 35234328.
Alvarez H, Ruiz-Mateos E, Juiz-Gonzalez PM, Vitalle J, Vieitez I,Vazquez-Friol MDC, Torres-Beceiro I, Perez-Gomez A, Gallego-Garcia P,Estevez-Gomez N, De Chiara L, Poveda E, Posada D, Llibre JM. SARS-CoV-2 Evolutionand Spike-Specific CD4+ T-Cell Response in Persistent COVID-19 with Severe HIVImmune Suppression. Microorganisms. 2022 Jan 11;10(1):143. doi:10.3390/microorganisms10010143. PubMed PMID: 35056592; PubMed Central PMCID:PMC8780218.
Enlace
Perez-Gomez A, Gasca-Capote C, Vitalle J, Ostos FJ, Serna-Gallego A,Trujillo-Rodriguez M, Munoz-Muela E, Giraldez-Perez T, Praena-Segovia J,Navarro-Amuedo MD, Paniagua-Garcia M, Garcia-Gutierrez M, Aguilar-Guisado M,Rivas-Jeremias I, Jimenez-Leon MR, Bachiller S, Fernandez-Villar A,Perez-Gonzalez A, Gutierrez-Valencia A, Rafii-El-Idrissi Benhnia M, Weiskopf D,Sette A, Lopez-Cortes LF, Poveda E, Ruiz-Mateos E; Virgen del Rocio HospitalCOVID-19 and COHVID-GS Working Teams. Deciphering the quality of SARS-CoV-2specific T-cell response associated with disease severity, immune memory andheterologous response. Clin Transl Med. 2022 Apr;12(4):e802. doi:10.1002/ctm2.802. PubMed PMID: 35415890; PubMed Central PMCID: PMC9005926.
Perez-Gonzalez A, Araujo-Ameijeiras A, Fernandez-Villar A, Crespo M, Poveda E;Cohort COVID-19 of the Galicia Sur Health Research Institute. Long COVID inhospitalized and non-hospitalized patients in a large cohort in Northwest Spain,a prospective cohort study. Sci Rep. 2022 Mar 1;12(1):3369. doi:10.1038/s41598-022-07414-x. Erratum In: Sci Rep. 2022 Aug 16;12(1):13873. PubMedPMID: 35233035; PubMed Central PMCID: PMC8888560.
Perez-Gonzalez A, Cachay E, Ocampo A, Poveda E. Update on the EpidemiologicalFeatures and Clinical Implications of Human Papillomavirus Infection (HPV) andHuman Immunodeficiency Virus (HIV) Coinfection. Microorganisms. 2022 May18;10(5):1047. doi: 10.3390/microorganisms10051047. PubMed PMID: 35630489; PubMedCentral PMCID: PMC9147826.
Perez-Gonzalez A, Represa M, Coll P, Potel C, Rodriguez-Rivero S, Flores EV,Vazquez-Estevez C, Ocampo A, Pousada G, Poveda E. Real-life cohort experienceafter implementing HIV pre-exposure prophylaxis for one year in northwest Spain.Front Public Health. 2022 Oct 28;10:1005622. doi: 10.3389/fpubh.2022.1005622.eCollection 2022. PubMed PMID: 36388349; PubMed Central PMCID: PMC9650222.
Perez-Gonzalez A, Suarez-Garcia I, Ocampo A, Poveda E. Two-Drug Regimens forHIV-Current Evidence, Research Gaps and Future Challenges. Microorganisms. 2022Feb 14;10(2):433. doi: 10.3390/microorganisms10020433. PubMed PMID: 35208887;PubMed Central PMCID: PMC8880461.
Poveda E, Tabernilla A, Fitzgerald W, Salgado-Barreira A, Grandal M, Perez A,Marino A, Alvarez H, Valcarce N, Gonzalez-Garcia J, Bernardino JI, Gutierrez F,Fujioka H, Crespo M, Ruiz-Mateos E, Margolis L, Lederman MM, Freeman ML. MassiveRelease of CD9+ Microvesicles in Human Immunodeficiency Virus Infection,Regardless of Virologic Control. J Infect Dis. 2022 Mar 15;225(6):1040-1049. doi:10.1093/infdis/jiaa375. PubMed PMID: 32603406; PubMed Central PMCID: PMC8922002.
Enlace
Trujillo-Rodriguez M, Munoz-Muela E, Serna-Gallego A, Praena-Fernandez JM,Perez-Gomez A, Gasca-Capote C, Vitalle J, Peraire J, Palacios-Baena ZR, CabreraJJ, Ruiz-Mateos E, Poveda E, Lopez-Cortes LE, Rull A, Gutierrez-Valencia A,Lopez-Cortes LF. Clinical, laboratory data and inflammatory biomarkers atbaseline as early discharge predictors in hospitalized SARS-CoV-2 infectedpatients. PLoS One. 2022 Jul 14;17(7):e0269875. doi:10.1371/journal.pone.0269875. eCollection 2022. PubMed PMID: 35834501; PubMedCentral PMCID: PMC9282584.
Artículos Científicos
Berenguer J, Díez C, Martín-Vicente M, Micán R, Pérez-Elías MJ, García-Fraile LJ, Vidal F, Suárez-García I, Podzamczer D, Del Romero J, Pulido F, Iribarren JA, Gutiérrez F, Poveda E, Galera C, Izquierdo R, Asensi V, Portilla J, López JC, Arribas JR, Moreno S, González-García J, Resino S, Jarrín I. Prevalence and factors associated with SARS-CoV-2 seropositivity in the Spanish HIV Research Network Cohort. Clin Microbiol Infect. 2021 Nov;27(11):1678–84. PMID: 34186209. DOI: 10.1016/j.cmi.2021.06.023. http://www.ncbi.nlm.nih.gov/pubmed/34186209
Enlace
Codina H, Vieitez I, Gutierrez-Valencia A, Skouridou V, Martinez C, Patino L,Botero-Gallego M, Trujillo-Rodriguez M, Serna-Gallego A, Munoz-Muela E, BobilloMM, Perez A, Cabrera-Alvar JJ, Crespo M, O’Sullivan CK, Ruiz-Mateos E, Poveda E.Elevated Anti-SARS-CoV-2 Antibodies and IL-6, IL-8, MIP-1beta, Early Predictors ofSevere COVID-19. Microorganisms. 2021 Oct 29;9(11):2259. doi:10.3390/microorganisms9112259. PubMed PMID: 34835384; PubMed Central PMCID:PMC8624589.
Enlace
Diez C, Del Romero-Raposo J, Mican R, Lopez JC, Blanco JR, Calzado S, SamperizG, Portilla J, Garcia-Fraile LJ, Gutierrez F, Gomez-Sirvent JL, Suarez-Garcia I,Amador C, Novella M, Arribas JR, Moreno S, Gonzalez-Garcia J, Jarrin I, BerenguerJ; for CoRIS (Eva Poveda). COVID-19 in hospitalized HIV-positive and HIV-negative patients: Amatched study. HIV Med. 2021 Oct;22(9):867-876. doi: 10.1111/hiv.13145. Epub 2021Jul 29. PubMed PMID: 34324783; PubMed Central PMCID: PMC8444663.
Lakoh S, Jiba DF, Vandy AO, Poveda E, Adekanmbi O, Murray MJS, Deen GF, Sahr F, Hoffmann CJ, Jacobson JM, Salata RA, Yendewa GA. Assessing eligibility for differentiated service delivery, HIV services utilization and virologic outcomes of adult HIV-infected patients in Sierra Leone: a pre-implementation analysis. Glob Health Action. 2021;14(1):1947566. PMID: 34404330. DOI: 10.1080/16549716.2021.1947566. http://www.ncbi.nlm.nih.gov/pubmed/34404330
Enlace
Pérez-Gómez A, Vitallé J, Gasca-Capote C, Gutierrez-Valencia A, Trujillo-Rodriguez M, Serna-Gallego A, Muñoz-Muela E, Jiménez-Leon M de LR, Rafii-El-Idrissi Benhnia M, Rivas-Jeremias I, Sotomayor C, Roca-Oporto C, Espinosa N, Infante-Domínguez C, Crespo-Rivas JC, Fernández-Villar A, Pérez-González A, López-Cortés LF, Poveda E, Ruiz-Mateos E, Virgen del Rocío Hospital COVID-19 Working Team. Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection. Cell Mol Immunol. 2021;18(9):2128–39. PMID: 34290398. DOI: 10.1038/s41423-021-00728-2. http://www.ncbi.nlm.nih.gov/pubmed/34290398
Enlace
Santos-Pereira A, Triunfante V, Araújo PMM, Martins J, Soares H, Poveda E, Souto B, Osório NS. Nationwide Study of Drug Resistance Mutations in HIV-1 Infected Individuals under Antiretroviral Therapy in Brazil. Int J Mol Sci. 2021 May;22(10):5304. PMID: 34069929. DOI: 10.3390/ijms22105304. http://www.ncbi.nlm.nih.gov/pubmed/34069929
Enlace
Suarez-Garcia I, Alejos B, Perez-Elias MJ, Iribarren JA, Hernando A, RamirezM, Tasias M, Pascual M, Jarrin I, Hernando V; CoRIS Cohort (Eva Poveda). How do women livingwith HIV experience menopause? Menopausal symptoms, anxiety and depressionaccording to reproductive age in a multicenter cohort. BMC Womens Health. 2021May 28;21(1):223. doi: 10.1186/s12905-021-01370-w. PubMed PMID: 34049547; PubMedCentral PMCID: PMC8162006.
Svobodova M, Skouridou V, Jauset-Rubio M, Vieitez I, Fernandez-Villar A,Cabrera Alvargonzalez JJ, Poveda E, Bofill CB, Sans T, Bashammakh A, Alyoubi AO,O’Sullivan CK. Aptamer Sandwich Assay for the Detection of SARS-CoV-2 SpikeProtein Antigen. ACS Omega. 2021 Dec 15;6(51):35657-35666. doi:10.1021/acsomega.1c05521. eCollection 2021 Dec 28. PubMed PMID: 34957366; PubMedCentral PMCID: PMC8691202.
Enlace
Yendewa GA, Lakoh S, Yendewa SA, Bangura K, Lawrence H, Patiño L, Jiba DF, Vandy AO, Murray MJS, Massaquoi SP, Deen GF, Sahr F, Hoffmann CJ, Jacobson JM, Poveda E, Aguilera A, Salata RA. Prevalence of hepatitis B surface antigen and serological markers of other endemic infections in HIV-infected children, adolescents and pregnant women in Sierra Leone: A cross-sectional study. Int J Infect Dis. 2021 Jan;102:45–52. PMID: 33002619. DOI: 10.1016/j.ijid.2020.09.1459. http://www.ncbi.nlm.nih.gov/pubmed/33002619
Enlace
Yendewa GA, Lakoh S, Yendewa SA, Bangura K, Tabernilla A, Patiño L, Jiba DF, Vandy AO, Massaquoi SP, Osório NS, Deen GF, Sahr F, Salata RA, Poveda E. Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone. Genes (Basel). 2021;12(9):1314. PMID: 34573296. DOI: 10.3390/genes12091314. http://www.ncbi.nlm.nih.gov/pubmed/34573296
Enlace
Artículos Científicos
Alejos B, Suárez-García I, Rava M, Bautista-Hernández A, Gutierrez F, Dalmau D, Sagastagoitia I, Rivero A, Moreno S, Jarrín I, CoRIS (Eva Poveda; Alexandre Pérez; Manuel Crespo; Luis Morano; Celia Miralles; Antonio Ocampo; Guillermo Pousada). Effectiveness and safety of first-line antiretroviral regimens in clinical practice: a multicentre cohort study. J Antimicrob Chemother. 2020 Oct;75(10):3004–14. PMID: 32667674. DOI: 10.1093/jac/dkaa246. http://www.ncbi.nlm.nih.gov/pubmed/32667674
Enlace
Lakoh S, Jiba DF, Adekanmbi O, Poveda E, Sahr F, Deen GF, Foray LM, Gashau W, Hoffmann CJ, Salata RA, Yendewa GA. Diagnosis and treatment outcomes of adult tuberculosis in an urban setting with high HIV prevalence in Sierra Leone: A retrospective study. Int J Infect Dis. International Society for Infectious Diseases; 2020 Jul;96:112–8. PMID: 32339724. DOI: 10.1016/j.ijid.2020.04.038. https://doi.org/10.1016/j.ijid.2020.04.038
Enlace
Ruiz-Mateos E, Poveda E, Lederman MM. Antiretroviral Treatment for HIV Elite Controllers? Pathog Immun. 2020;5(1):121–33. PMID: 32582872. DOI: 10.20411/pai.v5i1.364. http://www.ncbi.nlm.nih.gov/pubmed/32582872
Enlace
Serrano-Villar S, Martínez-Sanz J, Ron R, Talavera-Rodríguez A, Fernández-Felix BM, Herrera S, Muriel A, Fanjul F, Portilla J, Muñoz J, Amador C, de Zárraga MA, Vivancos MJ, Moreno S, Spanish HIV Research Network (CoRIS) (Eva Poveda; Alexandre Pérez; Manuel Crespo; Luis Morano; Celia Miralles; Antonio Ocampo; Guillermo Pousada). Effects of first-line antiretroviral therapy on the CD4/CD8 ratio and CD8 cell counts in CoRIS: a prospective multicentre cohort study. lancet HIV. 2020;7(8):e565–73. PMID: 32763219. DOI: 10.1016/S2352-3018(20)30202-2. http://www.ncbi.nlm.nih.gov/pubmed/32763219
Enlace
Suárez-García I, Alejos B, Delgado E, Rivero M, Pineda JA, Jarrin I, Cohort of the Spanish HIV/AIDS Network (CoRIS) study group (Eva Poveda). How well are we performing the initial assessment of HIV-positive patients? Results from a multicentre cohort in Spain. HIV Med. 2020;21(2):128–34. PMID: 31702111. DOI: 10.1111/hiv.12817. http://www.ncbi.nlm.nih.gov/pubmed/31702111
Enlace
Suárez-García I, Moreno C, Ruiz-Algueró M, Pérez-Elías MJ, Navarro M, Díez Martínez M, Viciana P, Pérez-Martínez L, Górgolas M, Amador C, de Zárraga MA, Jarrín I, Cohort of the Spanish HIV/ADS Research Network (CoRIS) (Eva Poveda; Alexandre Pérez; Manuel Crespo; Luis Morano; Celia Miralles; Antonio Ocampo; Guillermo Pousada). Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice: a multicentre cohort study. AIDS Res Ther. 2020;17(1):45. PMID: 32690099. DOI: 10.1186/s12981-020-00302-2. http://www.ncbi.nlm.nih.gov/pubmed/32690099
Enlace
Suárez-García I, Ruiz-Algueró M, García Yubero C, Moreno C, Belza MJ, Estébanez M, de Los Santos I, Masiá M, Samperiz Abad G, Muñoz Sánchez J, Omar M, Jarrín I, Cohort of the Spanish HIV/AIDS Research Network (CoRIS) (Eva Poveda; Alexandre Pérez; Manuel Crespo; Luis Morano; Celia Miralles; Antonio Ocampo; Guillermo Pousada). Physicians’ opinions on generic antiretroviral drugs and single-tablet regimen de-simplification for the treatment of HIV infection: a multicentre survey in Spain. J Antimicrob Chemother. 2020;75(2):466–72. PMID: 31665404. DOI: 10.1093/jac/dkz439. http://www.ncbi.nlm.nih.gov/pubmed/31665404
Enlace
Artículos Científicos
AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan: Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2018). Enferm Infecc Microbiol Clin. 2019;37(3):195–202. PMID: 29759422. DOI: 10.1016/j.eimc.2018.02.010. http://www.ncbi.nlm.nih.gov/pubmed/29759422
Enlace
AIDS Study Group (GeSIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology [Eva Poveda; Antonio Ocampo]. Executive summary of the GeSIDA consensus document on control and monitoring of HIV-infected patients. Enferm Infecc Microbiol Clin. 2019 May;37(7):467–75. PMID: 29793873. DOI: 10.1016/j.eimc.2018.03.011. http://www.ncbi.nlm.nih.gov/pubmed/29793873
Enlace
Alvarez M, Casas P, de Salazar A, Chueca N, Guerrero-Beltran C, Rodríguez C, Imaz A, Espinosa N, García-Bujalance S, Pérez-Elías MJ, García-Alvarez M, Iribarren JA, Santos J, Dalmau D, Aguilera A, Vinuesa D, Gutiérrez F, Piérola B, Molina JM, Peraire J, Portilla I, Gómez-Sirvent JL, Olalla J, Galera C, Blanco JR, Riera M, García-Fraile L, Navarro G, Curran A, Poveda E, García F, CoRIS. Surveillance of transmitted drug resistance to integrase inhibitors in Spain: implications for clinical practice. J Antimicrob Chemother. 2019 Jun;74(6):1693–700. PMID: 30838386. DOI: 10.1093/jac/dkz067. http://www.ncbi.nlm.nih.gov/pubmed/30838386
Enlace
Borrajo A, Ranazzi A, Pollicita M, Bellocchi MC, Salpini R, Mauro MV, Ceccherini-Silberstein F, Perno CF, Svicher V, Aquaro S. Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage. Medicina (Kaunas). 2019 Jun;55(6):297. PMID: 31234437. DOI: 10.3390/medicina55060297. http://www.ncbi.nlm.nih.gov/pubmed/31234437
Enlace
Cid-Silva P, Fernández-Bargiela N, Margusino-Framiñán L, Balboa-Barreiro V, Mena-De-Cea Á, López-Calvo S, Vázquez-Rodríguez P, Martín-Herranz I, Míguez-Rey E, Poveda E, Castro-Iglesias Á. Treatment with tenofovir alafenamide fumarate worsens the lipid profile of HIV-infected patients versus treatment with tenofovir disoproxil fumarate, each coformulated with elvitegravir, cobicistat, and emtricitabine. Basic Clin Pharmacol Toxicol. 2019 Apr;124(4):479–90. PMID: 30388308. DOI: 10.1111/bcpt.13161. http://www.ncbi.nlm.nih.gov/pubmed/30388308
Enlace
Cid-Silva P, Margusino-Framiñán L, Balboa-Barreiro V, Pernas-Souto B, Mena-De-Cea Á, Martín-Herranz I, Castro-Iglesias Á, Poveda E. Late HIV Diagnosis but Earlier Antiretroviral Treatment Initiation in Northwest Spain: Impact of Current Treatment Guidelines. J Int Assoc Provid AIDS Care. 2019 Jan;18:232595821882194. PMID: 30798655. DOI: 10.1177/2325958218821940. http://www.ncbi.nlm.nih.gov/pubmed/30798655
Enlace
De Mendoza C, Pirón M, Gonzalez R, Jiménez A, Caballero E, Roc L, Benito R, Ramos JM, Soriano V, HTLV Spanish Study Group (S Pérez; L Morano). Clinical Presentation of Individuals With Human T-Cell Leukemia Virus Type-1 Infection in Spain. Open forum Infect Dis. 2019 Feb;6(2):ofz036. PMID: 30815504. DOI: 10.1093/ofid/ofz036. http://www.ncbi.nlm.nih.gov/pubmed/30815504
Enlace
de Mendoza C, Roc L, Benito R, Reina G, Ramos JM, Gómez C, Aguilera A, Rodríguez-Iglesias M, García-Costa J, Fernández-Alonso M, Soriano V, Spanish HTLV Network (Eva Poveda). HTLV-1 infection in solid organ transplant donors and recipients in Spain. BMC Infect Dis. BMC Infectious Diseases; 2019 Aug;19(1):706. PMID: 31399112. DOI: 10.1186/s12879-019-4346-z. http://www.ncbi.nlm.nih.gov/pubmed/31399112
Enlace
de Mendoza C, Roc L, Fernández-Alonso M, Soriano V, Spanish HTLV Network (Eva Poveda). HTLV testing of solid organ transplant donors. Clin Transplant. 2019;33(10):e13670. PMID: 31321817. DOI: 10.1111/ctr.13670. http://www.ncbi.nlm.nih.gov/pubmed/31321817
Enlace
Lakoh S, Jiba DF, Kanu JE, Poveda E, Salgado-Barreira A, Sahr F, Sesay M, Deen GF, Sesay T, Gashau W, Salata RA, Yendewa GA. Causes of hospitalization and predictors of HIV-associated mortality at the main referral hospital in Sierra Leone: a prospective study. BMC Public Health. BMC Public Health; 2019 Oct;19(1):1320. PMID: 31638941. DOI: 10.1186/s12889-019-7614-3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805411/pdf/12889_2019_Article_7614.pdf
Enlace
Roc L, de Mendoza C, Fernández-Alonso M, Reina G, Soriano V, Spanish HTLV Network (Eva Poveda). Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals. Ther Adv Infect Dis. 2019;6(6):2049936119868028. PMID: 31467675. DOI: 10.1177/2049936119868028. http://www.ncbi.nlm.nih.gov/pubmed/31467675
Enlace
Yendewa GA, Sahr F, Aguilera A, Lakoh S, Sesay M, Deen GF, Patiño L, Poveda E, Salata RA. Seroprevalence of Hepatitis B, Hepatitis C, and Human T-Cell Lymphotropic Virus Infections in HIV-Infected Patients in Sierra Leone. Am J Trop Med Hyg. 2019 Jun;100(6):1521–4. PMID: 30938283. DOI: 10.4269/ajtmh.18-1001. http://www.ncbi.nlm.nih.gov/pubmed/30938283
Enlace
Yendewa GA, Sahr F, Lakoh S, Ruiz M, Patiño L, Tabernilla A, Deen GF, Sesay M, Salata RA, Poveda E. Prevalence of drug resistance mutations among ART-naive and -experienced HIV-infected patients in Sierra Leone. J Antimicrob Chemother. 2019 Apr;74(7):2024–9. PMID: 30989237. DOI: 10.1093/jac/dkz134. http://www.ncbi.nlm.nih.gov/pubmed/30989237
Enlace
Artículos Científicos
AIDS Study Group (GESIDA) of the Spanish Society of Infectious Diseases and Clinical Microbiology and the National AIDS Plan [Manuel Crespo; Eva Poveda]. Executive summary of the GESIDA/National AIDS Plan Consensus Document on Antiretroviral Therapy in Adults Infected by the Human Immunodeficiency Virus (Updated January 2017). Enferm Infecc Microbiol Clin. 2018 Aug;36(7):435–45. PMID: 28579016. DOI: 10.1016/j.eimc.2017.04.001. http://www.ncbi.nlm.nih.gov/pubmed/28579016
Enlace
Cid-Silva P, Margusino-Framiñán L, Balboa-Barreiro V, Martín-Herranz I, Castro-Iglesias Á, Pernas-Souto B, Llibre JM, Poveda E. Initial treatment response among HIV subtype F infected patients who started antiretroviral therapy based on integrase inhibitors. AIDS. 2018 Jan;32(1):121–5. PMID: 29112068. DOI: 10.1097/QAD.0000000000001679. http://www.ncbi.nlm.nih.gov/pubmed/29112068
Enlace
Grandal M, Pernas B, Tabernilla A, Mariño A, Álvarez H, Valcarce N, Mena A, Castro-Iglesias A, Pérez AB, Delgado M, Poveda E. Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies. J Med Virol. 2018 Jun;90(6):1094–8. PMID: 29427437. DOI: 10.1002/jmv.25048. http://www.ncbi.nlm.nih.gov/pubmed/29427437
Enlace
J A Fernández-Caballero, N Chueca, E Poveda, F García. A2?Optimization of the results generated by large-scale sequencing for the study of drug resistance in HIV infection: A systematic review. 22nd International BioInformatics Workshop on Virus Evolution and Molecular Epidemiology. Virus Evol. 2018 Apr; 4(Suppl 1): vey010.001. https://doi.org/10.1093/ve/vey010.001
Enlace
Poveda E, Crespo M. Hot News: Impact of Low-level Viremia on Treatment Outcomes During ART – Is it Time to Revise the Definition of Virological Failure? AIDS Rev. 2018;20(1):71–2. PMID: 29628513. http://www.ncbi.nlm.nih.gov/pubmed/29628513
Enlace
Yendewa GA, Poveda E, Lakoh S, Yendewa SA, Jiba DF, Salgado-Barreira A, Sahr F, Salata RA. High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone. Open forum Infect Dis. 2018 Sep;5(9):ofy208. PMID: 30191158. DOI: 10.1093/ofid/ofy208. http://www.ncbi.nlm.nih.gov/pubmed/30191158
Enlace
Yendewa GA, Poveda E, Yendewa SA, Sahr F, Quiñones-Mateu ME, Salata RA. HIV/AIDS in Sierra Leone: Characterizing the Hidden Epidemic. AIDS Rev. 2018 Apr;20(2):104–13. PMID: 29938704. DOI: 10.24875/AIDSRev.M18000022. http://www.ncbi.nlm.nih.gov/pubmed/29938704
Enlace
Artículos Científicos
Cid-Silva P, Llibre JM, Fernández-Bargiela N, Margusino-Framiñán L, Balboa-Barreiro V, Pernas-Souto B, Martín-Herranz I, Castro-Iglesias Á, Poveda E. Clinical Experience with the Integrase Inhibitors Dolutegravir and Elvitegravir in HIV-infected Patients: Efficacy, Safety and Tolerance. Basic Clin Pharmacol Toxicol. 2017 Nov;121(5):442–6. PMID: 28627771. DOI: 10.1111/bcpt.12828. IF2017:2.659; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28627771
Enlace
de Mendoza C, Caballero E, Aguilera A, Requena S, de Lejarazu RO, Pirón M, González R, Jiménez A, Roc L, Treviño A, Benito R, Fernández-Alonso M, Aguinaga A, Rodríguez C, García-Costa J, Blanco L, Ramos JM, Calderón E, Eirós JM, Sauleda S, Barreiro P, Soriano V, Spanish HTLV Network (Morano L; Pérez-Castro S; Poveda E). Human T-lymphotropic virus type 1 infection and disease in Spain. AIDS. 2017 Jul;31(12):1653–63. PMID: 28700391. DOI: 10.1097/QAD.0000000000001527. IF2017: 4.914; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28700391
Enlace
Fernández-Caballero JA, Chueca N, Poveda E, García F. Minimizing Next-Generation Sequencing Errors for HIV Drug Resistance Testing. AIDS Rev. 2017;19(4):231–8. PMID: 28534892. IF2017: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28534892
Enlace
Grandal M, Pernas B, Mariño A, Álvarez H, Tabernilla A, Castro-Iglesias Á, Mena Á, Delgado M, Pértega S, Poveda E. Characterization of chronic HCV infection in Northwest Spain: Impact of the treatment strategic plan of the Spanish National Health Service on HCV cure. J Med Virol. 2017 Jul;89(7):1304–8. PMID: 28079256. DOI: 10.1002/jmv.24766. IF2017: 1.988; Q3. http://www.ncbi.nlm.nih.gov/pubmed/28079256
Enlace
Meijide H, Mena Á, Rodríguez-Osorio I, Castro-Iglesias Á, Poveda E. Cancer Incidence in Persons Living With HIV. Clin Infect Dis. 2017 Feb;64(3):388–9. PMID: 28013260. DOI: 10.1093/cid/ciw759. IF2017: 9.117; D1. http://www.ncbi.nlm.nih.gov/pubmed/28013260
Enlace
Meijide H, Mena Á, Rodríguez-Osorio I, Pértega S, Castro-Iglesias Á, Rodríguez-Martínez G, Pedreira J, Poveda E. Trends in hospital admissions, re-admissions, and in-hospital mortality among HIV-infected patients between 1993 and 2013: Impact of hepatitis C co-infection. Enferm Infecc Microbiol Clin. 2017 Jan;35(1):20–6. PMID: 27609631. DOI: 10.1016/j.eimc.2016.07.012. IF2017: 1.707; Q3. http://www.ncbi.nlm.nih.gov/pubmed/27609631
Enlace
Meijide H, Pértega S, Rodríguez-Osorio I, Castro-Iglesias Á, Baliñas J, Rodríguez-Martínez G, Mena Á, Poveda E. Increased incidence of cancer observed in HIV/hepatitis C virus-coinfected patients versus HIV-monoinfected. AIDS. 2017 May;31(8):1099–107. PMID: 28441174. DOI: 10.1097/QAD.0000000000001448. IF2017: 4.914; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28441174
Enlace
Mena A, Meijide H, Rodríguez-Osorio I, Castro A, Poveda E. Liver-related mortality and hospitalizations attributable to chronic hepatitis C virus coinfection in persons living with HIV. HIV Med. 2017 Oct;18(9):685–9. PMID: 28230318. DOI: 10.1111/hiv.12502. IF2017: 2.932; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28230318
Enlace
Pernas B, Rego-Pérez I, Tabernilla A, Balboa V, Relaño S, Grandal M, Crespo M, Mena Á, Castro-Iglesias Á, Blanco FJ, Poveda E. Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication. J Antimicrob Chemother. 2017 Nov;72(11):3159–62. PMID: 28961892. DOI: 10.1093/jac/dkx272. IF2017: 5.217; D1. http://www.ncbi.nlm.nih.gov/pubmed/28961892
Enlace
Poveda E, Crespo M. When is Early Antiretroviral Therapy Early Enough for HIV Remission? AIDS Rev. 2017 Apr;19(2):113–4. PMID: 28534887. IF2017: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28534887
Enlace
Poveda E, Freeman ML. Hot News: Exosomes as New Players in HIV Pathogenesis – New Data from the IAS 2017. AIDS Rev. 2017;19(3):173–5. PMID: 29019351. IF2017: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/29019351
Enlace
Poveda E, Hernández-Quero J, Pérez-Elías MJ, Ribas MA, Martínez-Madrid OJ, Flores J, Navarro J, Gutiérrez F, García-Deltoro M, Imaz A, Ocampo A, Artero A, Blanco F, Bernal E, Pasquau J, Mínguez-Gallego C, Pérez N, Aiestaran A, García F, Paredes R, PROTEST study group. Genotypic tropism testing of proviral DNA to guide maraviroc initiation in aviraemic subjects: 48-week analysis of results from the PROTEST study. HIV Med. 2017 Aug;18(7):482–9. PMID: 28035758. DOI: 10.1111/hiv.12479. IF2017: 2.932; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28035758
Enlace
Poveda E, Martin-Gayo E. Similar Immunological Profiles Between Nonprogressing HIV Infection in Children and Nonpathogenic SIV Infection. AIDS Rev. 2017;19(1):54–5. PMID: 28182614. IF2017: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28182614
Enlace
Poveda E, Puoti M, García-Deltoro M, Pineda JA, Téllez F, Granados R, Morano L, García F, Grupo de Estudio de Hepatitis Víricas (GEHEP). News on Viral Hepatitis in HIV: Update from the 2016 GEHEP Conference. AIDS Rev. 2017 Jan;19(1):47–53. PMID: 28182613. IF2017: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28182613
Enlace
Rodríguez-Osorio I, Cid P, Morano L, Castro Á, Suárez M, Delgado M, Margusino L, Meijide H, Pernas B, Tabernilla A, Pedreira JD, Mena Á, Poveda E. Real life experience with direct-acting antivirals agents against hepatitis C infection in elderly patients. J Clin Virol. 2017 Mar;88:58–61. PMID: 28183063. DOI: 10.1016/j.jcv.2017.01.003. IF2017: 3.101; Q2. http://www.ncbi.nlm.nih.gov/pubmed/28183063
Enlace
Tabernilla A, Grandal M, Pernas B, Castro-Iglesias A, Rodríguez-Osorio I, Mena A, Delgado M, Cid P, Pedreira JD, Poveda E. Short article: Viral dynamics among hepatitis C virus chronic infected patients during direct-acting antiviral agents therapy: impact for monitoring and optimizing treatment duration. Eur J Gastroenterol Hepatol. 2017 Jul;29(7):781–5. PMID: 28410351. DOI: 10.1097/MEG.0000000000000882. IF2017: 2.014; Q4. http://www.ncbi.nlm.nih.gov/pubmed/28410351
Enlace
Treviño A, Aguilera A, Rodríguez-Iglesias MA, Hernandez A, Benito R, Roc L, Ramos JM, Ortíz de Lejarazu R, Poveda E, Rodríguez C, Del Romero J, Calderon E, García J, Requena S, Soriano V, de Mendoza C. HTLV infection in HCV-antibody positive patients in Spain. AIDS Res Hum Retroviruses. 2017 Mar;33(10):1013–7. PMID: 28269998. DOI: 10.1089/AID.2016.0323. IF2017: 1.935; Q3. http://www.ncbi.nlm.nih.gov/pubmed/28269998
Enlace
Artículos Científicos
Pernas B, Grandal M, Pertega S, Cañizares A, Castro-Iglesias Á, Mena Á, Rodriguez-Osorio I, Tabernilla A, Pedreira JD, Poveda E. Any impact of blips and low-level viraemia episodes among HIV-infected patients with sustained virological suppression on ART? J Antimicrob Chemother. 2016 Apr;71(4):1051–5. PMID: 26702924. DOI: 10.1093/jac/dkv433. http://www.ncbi.nlm.nih.gov/pubmed/26702924
Enlace
Pernas B, Grandal M, Tabernilla A, Cid P, Pértega S, Castro-Iglesias Á, Mena Á, Margusino L, Pedreira JD, Poveda E. Long-term clinical experience with darunavir (2007-2015) in a large cohort of HIV-infected patients in Spain. J Med Virol. 2016;88(12):2125–31. PMID: 27218208. DOI: 10.1002/jmv.24585. http://www.ncbi.nlm.nih.gov/pubmed/27218208
Enlace
Poveda E, Crespo M. New Strategies for a Comprehensive Fight Against HIV Infection using Monoclonal Antibody Therapy. AIDS Rev. 2016 Jul;18(3):166. PMID: 27721508. IF2016: 3.195; Q2. http://www.ncbi.nlm.nih.gov/pubmed/27721508
Enlace
Poveda E, Tabernilla A. New Insights into HIV-1 Persistence in Sanctuary Sites During Antiretroviral Therapy. AIDS Rev. 2016;18(1):55. PMID: 27028272. http://www.ncbi.nlm.nih.gov/pubmed/27028272
Enlace
Tabernilla A, Rego-Pérez I, Grandal M, Pernas B, Pértega S, Delgado M, Mariño A, Álvarez H, Mena A, Rodríguez-Osorio I, Pedreira JD, Blanco FJ, Poveda E. Brief Report: European Mitochondrial Haplogroups Impact on Liver Fibrosis Progression Among HCV and HIV/HCV-Coinfected Patients From Northwest Spain. J Acquir Immune Defic Syndr. 2016;73(2):149–53. PMID: 27258234. DOI: 10.1097/QAI.0000000000001097. http://www.ncbi.nlm.nih.gov/pubmed/27258234
Enlace
Artículos Científicos
Meijide H, Mena A, Marcos PJ, Rodriguez-Osorio I, Suárez-Fuentetaja R, Castro A, Poveda E, Pedreira JD. Lung cancer in patients living with HIV infection. AIDS. 2015 Nov;29(17):2363–4. PMID: 26544707. DOI: 10.1097/QAD.0000000000000840. IF2015: 4.407; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26544707
Enlace
Paraskevis D, Kostaki E, Beloukas A, Cañizares A, Aguilera A, Rodríguez J, Grandal M, Pernas B, Castro-Iglesias A, Mena Á, Pedreira JD, Poveda E. Molecular characterization of HIV-1 infection in Northwest Spain (2009-2013): Investigation of the subtype F outbreak. Infect Genet Evol. 2015 Mar;30:96–101. PMID: 25527396. DOI: 10.1016/j.meegid.2014.12.012. http://www.ncbi.nlm.nih.gov/pubmed/25527396
Enlace
Pernas B, Mena A, Cañizares A, Grandal M, Castro-Iglesias A, Pértega S, Pedreira JD, Poveda E. Trends on epidemiological, virological, and clinical features among newly diagnosed HIV-1 persons in Northwest Spain over the last 10 years. J Med Virol. 2015 Aug;87(8):1319–26. PMID: 25777786. DOI: 10.1002/jmv.24185. http://www.ncbi.nlm.nih.gov/pubmed/25777786
Enlace
Poveda E, Wyles D, Morano L, Pineda JA, García F, Grupo de Estudio de Hepatitis Víricas (GEHEP), E P, D W, L M, JA P, F G, GEHEP. News on HIV-HCV coinfection: Update from the 2015 GEHEP conference. AIDS Rev. 2015 Oct;17(4):231–7. PMID: 26616846. IF2015: 2.068; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26616846
Enlace
Poveda E. Discovery of a Natural Defense Against HIV With Therapeutic Potential. AIDS Rev. 2015;17(4):238. PMID: 26690492. IF2015: 2.068; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26690492
Enlace
Poveda E. HIV tropism shift: new paradigm on cell therapy strategies for HIV cure. AIDS Rev. 2015;17(1):65. PMID: 25608470. IF2015: 2.068; Q3. http://www.ncbi.nlm.nih.gov/pubmed/25608470
Enlace
Tabernilla A, Poveda E. The START Trial: Definitive Evidence to Treat All HIV-Positive Persons Regardless of CD4 Counts. AIDS Rev. 2015;17(3):187. PMID: 26450809. IF2015: 2.068; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26450809
Enlace
Treviño A, Caballero E, de Mendoza C, Aguilera A, Pirón M, Soriano V, Spanish HIV-2/HTLV Study Group. The Burden of Neglected HIV-2 and HTLV-1 Infections in Spain. AIDS Rev. 2015;17(4):212–9. PMID: 26616845. IF2015: 2.068; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26616845
Enlace
Artículos Científicos
de Mendoza C, Caballero E, Aguilera A, Pirón M, Ortiz de Lejarazu R, Rodríguez C, Cabezas T, González R, Treviño A, Soriano V, Spanish HIV-2/HTLV Group. HIV-2 and HTLV-1 infections in Spain, a non-endemic region. AIDS Rev. 2014;16(3):152–9. PMID: 25180694. IF2014: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/25180694
Enlace
Garcia F, Poveda E, Pérez-Elías MJ, Quero JH, Ribas MA, Martínez-Madrid OJ, Flores J, Crespo M, Gutiérrez F, García-Deltoro M, Imaz A, Ocampo A, Artero A, Blanco F, Bernal E, Pasquau J, Mínguez-Gallego C, Pérez N, Aiestarán A, Paredes R. Genotypic tropism testing in proviral DNA to guide maraviroc initiation in aviremic subjects: 48-week analysis of the PROTEST study. J Int AIDS Soc. 2014 Jan;17(4 Suppl 3):19520. PMID: 25394029. DOI: 10.7448/ias.17.4.19520. IF: 5.090; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25394029
Enlace
Mena A, Moldes L, Meijide H, Cañizares A, Castro-Iglesias A, Delgado M, Pértega S, Pedreira J, Bou G, Poveda E. Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing. PLoS One. 2014;9(12):e113062. PMID: 25436642. DOI: 10.1371/journal.pone.0113062. IF2014: 3.234; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25436642
Enlace
Mena Á, Pedreira JD, Castro Á, López S, Vázquez P, Poveda E. Metabolic syndrome association with fibrosis development in chronic hepatitis B virus inactive carriers. J Gastroenterol Hepatol. 2014 Jan;29(1):173–8. PMID: 24219115. DOI: 10.1111/jgh.12432. IF2014: 3.504; Q2. http://www.ncbi.nlm.nih.gov/pubmed/24219115
Enlace
Monge S, Guillot V, Alvarez M, Chueca N, Stella N, Peña A, Delgado R, Córdoba J, Aguilera A, Vidal C, García F, CoRIS. Clinically relevant transmitted drug resistance to first line antiretroviral drugs and implications for recommendations. PLoS One. 2014;9(3):e90710. PMID: 24637804. DOI: 10.1371/journal.pone.0090710. IF2014: 3.234; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24637804
Enlace
Pernas B, Grandal M, Mena A, Castro-Iglesias A, Cañizares A, Wyles DL, López-Calvo S, Pértega S, Rodríguez-Osorio I, Pedreira JD, Poveda E. High prevalence of subtype F in newly diagnosed HIV-1 persons in northwest Spain and evidence for impaired treatment response. AIDS. 2014 Jul;28(12):1837–40. PMID: 24871456. DOI: 10.1097/QAD.0000000000000326. IF2014: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/24871456
Enlace
Poveda E, Pedreira JD. Highlights from CROI 2014 on experimental HIV drugs. AIDS Rev. 2014;16(2):118. PMID: 24984767. IF2014: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/24984767
Enlace
Poveda E, Wyles DL, Mena A, Pedreira JD, Castro-Iglesias A, Cachay E. Update on hepatitis C virus resistance to direct-acting antiviral agents. Antiviral Res. 2014 Aug;108(1):181–91. PMID: 24911972. DOI: 10.1016/j.antiviral.2014.05.015. http://www.ncbi.nlm.nih.gov/pubmed/24911972
Enlace
Poveda E. Ingenol derivates promising for HIV eradication. AIDS Rev. 2014;16(4):246. PMID: 25373349. IF2014: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/25373349
Enlace
Poveda E. Multi-step inhibition against HIV lifecycle-underlying the “magic” of protease inhibitors. AIDS Rev. 2014;16(1):52. PMID: 24589971. IF2014: 2.775; Q2. http://www.ncbi.nlm.nih.gov/pubmed/24589971
Enlace
Treviño A, Soriano V, Poveda E, Parra P, Cabezas T, Caballero E, Roc L, Rodríguez C, Eiros JM, Lopez M, De Mendoza C, HIV-2 Spanish Study Group. HIV-2 viral tropism influences CD4+ T cell count regardless of viral load. J Antimicrob Chemother. 2014 Aug;69(8):2191–4. PMID: 24788659. DOI: 10.1093/jac/dku119. IF: 5.313; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24788659
Enlace
