Uropatología
Principales líneas de investigación
- HER2 como marcador predictivo en el cáncer no musculo-invasivo de vejiga
- PD-L1 como marcador molecular pronóstico en el carcinoma renal mestastásico
- Infección por virus del papiloma humano (VPH) en el hombre y su implicación en el cáncer de cuello de útero en su pareja sexual
- Estudio de marcadores pronósticos en el cáncer de pene relacionado con la infección por virus del papiloma humano(VPH)
- Microbiota y cáncer de próstata
Investigadores Responsables
Investigadores Colaboradores
Artículos Científicos
Carballo Quinta M, Perez Castro S, Freire Rodriguez A, Davina Nunez C, BellasPereira A, Cabrera Alvargonzalez JJ, Perez Schoch M, Muller Arteaga CA, SanchezGarcia JF, Cespon Outeda E, Lopez Diez E. Gut microbiota and prostate cancer: Ananalysis of bacterial communities across various clinical scenarios. Actas UrolEsp (Engl Ed). 2025 Jun;49(5):501748. doi: 10.1016/j.acuroe.2025.501748. Epub2025 Apr 19. English, Spanish. PubMed PMID: 40258415.
Enlace
Cespon-Fernandez M, Escalona-Canal EJ, Sanchez-Ramos J, Raposeiras-Roubin S,Abdulkader-Sande S, Cobas-Paz RJ, Torreira-Banzas C, Abu-Assi E,Teijeira-Bautista S, Dominguez-Aristegui P, Garcia-Pavia P, Escalona-Canal ME,Cespon-Outeda E, Ortiz-Rey JA. Amyloid deposits in prostate biopsy as anopportunity to diagnose early cardiac amyloidosis. J Geriatr Cardiol. 2025 Jan28;22(1):169-177. doi: 10.26599/1671-5411.2025.01.007. PubMed PMID: 40151629;PubMed Central PMCID: PMC11937828.
Artículos Científicos
Ortiz-Rey JA, Garcia-Baizan A, Bellas-Pereira A, Barciela-Bastos A, Gomez-deMaria C, Conde-Ferreiros M. Myxoid Pseudotumor Changes Affecting the DistalUreter Associated With Urothelial Carcinoma In Situ. Int J Surg Pathol. 2024Jun;32(4):772-775. doi: 10.1177/10668969231188894. Epub 2023 Jul 31. PubMed PMID:37525552.
Ortiz-Rey JA, Sanchez-Ramos J, Abdulkader-Sande S, Munoz-Raya D, Aguayo-ArjonaJ, Fernandez-Costas A, Gomez-de Maria C, Liste-Tizon L, Escalona-Canal EJ,Raposeiras-Roubin S, Cobas-Paz RJ, San Miguel-Fraile P, Cespon-Outeda E,Cespon-Fernandez M. Prostatic amyloidosis: pathological features of anunderdiagnosed condition. Virchows Arch. 2024 Dec 23. doi:10.1007/s00428-024-04014-0. Online ahead of print. PubMed PMID: 39715953.
Artículos Científicos
Bellas-Pereira A, Betancor Santos MLA, Lopez Castello A, Perez Costas M,Otero-Garcia M, San Miguel-Fraile P, Dominguez-Aristegui P, Ortiz-Rey JA. RenalAngiomyolipoma: A Diagnostic and Therapeutic Challenge. Arch Esp Urol. 2023Mar;76(2):169-174. doi: 10.56434/j.arch.esp.urol.20237602.19. PubMed PMID:37139623.
Ortiz-Rey JA, Alvarez-Sarria M, Conde-Ferreiros M, Morellon-Baquera R,Bellas-Pereira A, Baltazar ST, Garcia-Acuna S, San-Miguel Fraile P,Suarez-Penaranda JM, Fernandez-Baltar C, Vieytes-Molares M, Dominguez-AristeguiP, Gomez-de Maria C, Fachal-Bermudez C, Gonzalez-Carrero J. SATB2 as a Marker ofthe Proximal Nephron: Expression in Nephrogenic Adenoma and Correlation WithOther Renal Tubular Markers. Appl Immunohistochem Mol Morphol. 2023 Mar1;31(3):145-153. doi: 10.1097/PAI.0000000000001103. Epub 2023 Feb 6. PubMed PMID:36744623.
Segui-Moya E, Amoros-Torres A, Centeno-Alvarez C, Gutierrez-Zurimendi G, Nunode la Rosa I, Escudero-Fontano E, Sierra Del Rio A, Moreno-Fontela MP,Sanchez-Garcia M, Mir-Maresma MC, Musquera-Felip M, Ribal-Caparros MJ, Lopez-DiezE, Gonzalez-Enguita C. Women in urology: what is their current situation inSpain? Actas Urol Esp (Engl Ed). 2023 Sep;47(7):462-469. doi:10.1016/j.acuroe.2023.07.005. Epub 2023 Jul 11. English, Spanish. PubMed PMID:37442224.
Williamson SR, Hes O, Trpkov K, Aggarwal A, Satapathy A, Mishra S, Sharma S,Sangoi A, Cheng L, Akgul M, Idrees M, Levin A, Sadasivan S, San Miguel Fraile P,Rogala J, Comperat E, Berney DM, Bulimbasic S, McKenney JK, Jha S, Sampat NY,Mohanty SK. Low-grade oncocytic tumour of the kidney is characterised by geneticalterations of TSC1, TSC2, MTOR or PIK3CA and consistent GATA3 positivity.Histopathology. 2023 Jan;82(2):296-304. doi: 10.1111/his.14816. Epub 2022 Oct 18.PubMed PMID: 36208048.
Artículos Científicos
Chantada-de la Fuente D, San Miguel-Fraile MP, Serantes Combo A, Ortiz-Rey JA,Gandara-Cortes M, Fernandez-Martin J. IgG4-related disease diagnosed in aparatesticular pseudotumor simulating malignancy, in a patient withretroperitoneal fibrosis. Rev Esp Patol. 2022 Sep;55 Suppl 1:S2-S6. doi:10.1016/j.patol.2020.10.003. Epub 2020 Dec 11. PubMed PMID: 36075657.
Conde-Ferreiros M, Dominguez-de Dios J, Juaneda-Magdalena L, Bellas-Pereira A,San Miguel Fraile MP, Peteiro Cancelo MA, Gomez-de Maria C, Alvarez Sarria M,Betancor Santos MA, Gonzalez-Carrero J, Ortiz-Rey JA. Papillary renal cellneoplasm with reverse polarity: A new subtype of renal tumour with favorableprognosis. Actas Urol Esp (Engl Ed). 2022 Dec;46(10):600-605. doi:10.1016/j.acuroe.2022.05.002. Epub 2022 Aug 3. English, Spanish. PubMed PMID:36216763.
Ortiz-Rey JA, Bellas-Pereira A, San Miguel-Fraile P, Morellon-Baquera R,Dominguez-Aristegui P, Gonzalez-Carrero Fojon J. Intraductal Carcinoma of theProstate without High-Grade Invasive Adenocarcinoma: Report of Two Cases andReview of the Literature. Arch Esp Urol. 2022 Nov;75(9):738-745. doi:10.56434/j.arch.esp.urol.20227509.108. PubMed PMID: 36472055.
Artículos Científicos
Ortiz-Rey J-A, Fachal C, Juaneda-Magdalena L, Muñoz-Martín M, Repáraz-Andrade A, Teijeira S, Lamas-Barreiro J-M, Almuster-Domínguez S, San Miguel-Fraile P, Gómez-de María C. Clear cell clusters in the kidney: a rare finding that should not be misdiagnosed as renal cell carcinoma. Virchows Arch. 2021 Jul;479(1):57–67. PMID: 33447899. DOI: 10.1007/s00428-021-03018-4. http://www.ncbi.nlm.nih.gov/pubmed/33447899
Enlace
Artículos Científicos
Ortiz-Rey JA, Domínguez-de Dios J, Pérez-Schoch M, San Miguel-Fraile P, Gómez-de María C. [E-Cadherine and GATA-3 are useful in the confirmation of the vas deferens in vasectomy specimens]. Rev Esp Patol. 2020 Oct;53(4):218–25. PMID: 33012491. DOI: 10.1016/j.patol.2020.02.005. https://doi.org/10.1016/j.patol.2020.02.005
Enlace
Ortiz-Rey JA, Domínguez-de Dios J, Pérez-Schoch M, San Miguel-Fraile P, Gómez-de María C. [New immunohistochemistry markers to determine presence of vas deferens in vasectomy specimen.]. Arch Esp Urol. 2020 Jul;73(6):534–40. PMID: 32633248. http://www.ncbi.nlm.nih.gov/pubmed/32633248
Enlace
Artículos Científicos
Trpkov K, Williamson SR, Gao Y, Martinek P, Cheng L, Sangoi AR, Yilmaz A, Wang C, San Miguel Fraile P, Perez Montiel DM, Bulimbasi? S, Rogala J, Hes O. Low-grade oncocytic tumour of kidney (CD117-negative, cytokeratin 7-positive): a distinct entity? Histopathology. 2019 Aug;75(2):174–84. PMID: 30895640. DOI: 10.1111/his.13865. http://www.ncbi.nlm.nih.gov/pubmed/30895640
Enlace
Artículos Científicos
Gómez-de María C, Ortiz-Rey JA, Fernández-Costas A, Martínez-Otero M, Gándara-Cortés M, Blanco-Fernández MJ, Barbosa-Barreiro MJ, San Miguel-Fraile MP, Castro-Iglesias M, Antón-Badiola I, González-Carreró J, López-Díez ME. [Tissue arrays: Two simple and economical methods for manual construction.]. Arch Esp Urol. 2018 Dec;71(10):832–9. PMID: 30560794. http://www.ncbi.nlm.nih.gov/pubmed/30560794
Enlace
Osorio-Velásquez A, Chiesa-Estomba CM, Betances-Reinoso FA, San Miguel-Fraile MP, Ortiz-Rey JA. [Sarcomatoid carcinoma of larynx. A histological challenge?]. Rev Esp Patol. 2018 Jan;51(1):30–3. PMID: 29290320. DOI: 10.1016/j.patol.2016.09.004. http://www.ncbi.nlm.nih.gov/pubmed/29290320
Enlace
Artículos Científicos
Blanco LT, Socarras MR, Montero RF, Diez EL, Calvo AO, Gregorio SAY, Cansino JR, Galan JA, Rivas JG. Renal colic during pregnancy: Diagnostic and therapeutic aspects. Literature review. Cent Eur J Urol. 2017;70(1):93–100. PMID: 28461996. DOI: 10.5173/ceju.2017.754.
Lopez Diez E, Perez S, Inarrea A, de la Orden A, Castro MM, Almuster S, Tortolero L, Rodriguez M, Montero R, Ojea A, López Diez E, Pérez S, Iñarrea A, de la Orden A, Castro MM, Almuster S, Tortolero L, Rodríguez M, Montero R, Ojea A. Prevalence and concordance of high-risk papillomavirus infection in male sexual partners of women diagnosed with high grade cervical lesions. Enferm Infecc Microbiol Clin. 2017 May;35(5):273–7. PMID: 27004428. DOI: 10.1016/j.eimc.2016.02.014. IF2017: 1.707; Q3. http://www.ncbi.nlm.nih.gov/pubmed/27004428
Enlace
Lopez-Diez E, Perez S, Carballo M, Iñarrea A, de la Orden A, Castro M, Rodríguez M, Almuster S, Montero R, Perez M, Sanchez J, Ojea A. Lifestyle factors and oncogenic papillomavirus infection in a high-risk male population. PLoS One. 2017 Nov;12(9):e0184492. PMID: 28898279. DOI: 10.1371/journal.pone.0184492. http://www.ncbi.nlm.nih.gov/pubmed/28898279
Enlace
Ortiz-Rey JA, Chantada-de la Fuente D, Peteiro-Cancelo MÁ, Gómez-de María C, San Miguel-Fraile MP. Usefulness of GATA-3 as a marker of seminal epithelium in prostate biopsies. Actas Urol Esp. 2017 Nov;41(9):577–83. PMID: 28461097. DOI: 10.1016/j.acuro.2017.03.004. http://www.ncbi.nlm.nih.gov/pubmed/28461097
Enlace
Perez S, Iñarrea A, Pérez-Tanoira R, Gil M, López-Díez E, Valenzuela O, Porto M, Alberte-Lista L, Peteiro-Cancelo MA, Treinta A, Carballo R, Reboredo MC, Alvarez-Argüelles ME, Purriños MJ. Fraction of high-grade cervical intraepithelial lesions attributable to genotypes targeted by a nonavalent HPV vaccine in Galicia, Spain. Virol J. 2017 Dec;14(1):214. PMID: 29110680. DOI: 10.1186/s12985-017-0879-1. IF2017: 2.465; Q3. http://www.ncbi.nlm.nih.gov/pubmed/29110680
Enlace
Artículos Científicos
Lopez Diez E, Perez S, Inarrea A, la Orden A de, Castro M, Diz JC, Almuster S. Acetowhite Test for Detection of Papilloma Virus Infection in Men Sexual Partner of Women Diagnosed of High Grade Cervical Lesions. J Womens Heal Issues Care. 2016 Jun;5(5) DOI: 10.4172/2325-9795.1000244. http://www.doi.org/10.4172/2325-9795.1000244
Enlace
Artículos Científicos
Fernandez Eire P, Lemos Bouzas MX, Ortiz Rey JA, Herreros Villaraviz M, Prada Arias M. Benign cystic mesothelioma in a boy: An uncommon case mimicking a lymphangioma. J Paediatr Child Health. 2015 Aug;51(8):841–2. PMID: 26223760. DOI: 10.1111/jpc.12961. IF2015: 1.477; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26223760
Enlace
López Vázquez Y, Penín Álvarez M, San Miguel Fraile P, Barragáns Pérez M. Risk of malignancy in thyroid nodules with atipia of undetermined significance. Endocrinol y Nutr o?rgano la Soc Espan?ola Endocrinol y Nutr. 2015 Dec;62(10):507–10. PMID: 26526719. DOI: 10.1016/j.endonu.2015.06.007. IF2015: 1.314; Q4. http://www.ncbi.nlm.nih.gov/pubmed/26526719
Enlace
Ortiz-Rey JA, Juaneda-Benavides L, Peteiro-Cancelo Á, de María CG, Tejado BSM, Tardío-Baigés A. Another application of PAX8: to confirm the presence of seminal vesicle epithelium in prostate needle biopsies. Appl Immunohistochem Mol Morphol AIMM. 2015 Feb;23(2):161–2. PMID: 25153494. DOI: 10.1097/PAI.0000000000000016. IF2015: 1.553; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25153494
Enlace
Artículos Científicos
López-Díaz E, Freire-Calvo J, de la Orden A, Jamardo González D, Carballo Quinta M, Ojea Calvo A. Relevancia clínica del estudio urodinámico en el tratamiento de la incontinencia. Suelo pélvico Rev española sobre Med del suelo pélvico la mujer y cirugía Reconstr. 2014;10(2):39–42. IF2019: N/A. https://dialnet.unirioja.es/servlet/articulo?codigo=6409372
Enlace
Núñez EC, Peñaranda JMS, Alonso MSM, Ortiz-Rey JA. Acquired vulvar lymphangioma: a case series with emphasis on expanding clinical contexts. Int J Gynecol Pathol. 2014 May;33(3):235–40. PMID: 24681732. DOI: 10.1097/PGP.0b013e31829655cb. IF: 1.665; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24681732
Enlace
Ortiz-Rey JA, Alberte-Lista LM, Mateos-Martín A, López-García S. Mucinous, tubular and spindle cell carcinoma of kidney: report of two cases with pathological differences. Arch españoles Urol. 2014 Nov;67(9):784–8. PMID: 25407154. IF: 0.309; Q4. http://www.ncbi.nlm.nih.gov/pubmed/25407154
Enlace
