– Nanomedicine. Biocompatibility: toxicity and immune response to nanoparticles – Vaccines: Immune response to several prototypes / Tuberculosis – Generation of monoclonal antibodies with different applications – Development of biosensors – Bioinformatics: Genomic and Transcriptomic – Immunotherapy / Autoimmune diseases – Modelling the immune response
Immunology · IIS Galicia Sur
2017
2018
2019
2020
Scientific Papers
González-Ballesteros N, Diego-González L, Lastra-Valdor M, Grimaldi M, Cavazza A, Bigi F, Rodríguez-Argüelles MC, Simón-Vázquez R. Saccorhiza polyschides used to synthesize gold and silver nanoparticles with enhanced antiproliferative and immunostimulant activity. Mater Sci Eng C Mater Biol Appl. 2021 Apr;123:111960. PMID: 33812588. DOI: 10.1016/j.msec.2021.111960. http://www.ncbi.nlm.nih.gov/pubmed/33812588 +Pubmed+DOI
Magadan S, Mondot S, Palti Y, Gao G, Lefranc MP, Boudinot P. Genomic analysis of a second rainbow trout line (Arlee) leads to an extended description of the IGH VDJ gene repertoire. Dev Comp Immunol. 2021 May;118:103998. PMID: 33450314. DOI: 10.1016/j.dci.2021.103998. http://www.ncbi.nlm.nih.gov/pubmed/33450314 +Pubmed+DOI
Martínez-Pérez A, Igea A, Estévez O, Ferreira CM, Torrado E, Castro AG, Fernández C, Spetz A-L, Adam L, López González M, Singh M, Reljic R, González-Fernández Á. Changes in the Immune Phenotype and Gene Expression Profile Driven by a Novel Tuberculosis Nanovaccine: Short and Long-Term Post-immunization. Front Immunol. 2021;11:589863. PMID: 33584654. DOI: 10.3389/fimmu.2020.589863. http://www.ncbi.nlm.nih.gov/pubmed/33584654 +Pubmed+DOI
Oliveira IM, Gonçalves C, Oliveira EP, Simón-Vázquez R, da Silva Morais A, González-Fernández Á, Reis RL, Oliveira JM. PAMAM dendrimers functionalised with an anti-TNF ? antibody and chondroitin sulphate for treatment of rheumatoid arthritis. Mater Sci Eng C Mater Biol Appl. 2021 Feb;121:111845. PMID: 33579481. DOI: 10.1016/j.msec.2020.111845. http://www.ncbi.nlm.nih.gov/pubmed/33579481 +Pubmed+DOI
Varadé J, Magadán S, González-Fernández Á. Human immunology and immunotherapy: main achievements and challenges. Cell Mol Immunol. Springer US; 2021 Apr;18(4):805–28. PMID: 32879472. DOI: 10.1038/s41423-020-00530-6. http://www.ncbi.nlm.nih.gov/pubmed/32879472 +Pubmed+DOI
Scientific Papers
Biferi MG, Cohen-Tannoudji M, García-Silva A, Souto-Rodríguez O, Viéitez-González I, San-Millán-Tejado B, Fernández-Carrera A, Pérez-Márquez T, Teijeira-Bautista S, Barrera S, Domínguez V, Marais T, González-Fernández Á, Barkats M, Ortolano S. Systemic Treatment of Fabry Disease Using a Novel AAV9 Vector Expressing ?-Galactosidase A. Mol Ther Methods Clin Dev. 2020 Mar;20:1–17. PMID: 33335943. DOI: 10.1016/j.omtm.2020.10.016. http://www.ncbi.nlm.nih.gov/pubmed/33335943 +Pubmed+DOI
Diego-González L, Crecente-Campo J, Paul MJ, Singh M, Reljic R, Alonso MJ, González-Fernández Á, Simón-Vázquez R. Design of Polymeric Nanocapsules for Intranasal Vaccination against Mycobacterium Tuberculosis: Influence of the Polymeric Shell and Antigen Positioning. Pharmaceutics. 2020 May;12(6) PMID: 32481601. DOI: 10.3390/pharmaceutics12060489. http://www.ncbi.nlm.nih.gov/pubmed/32481601 +Pubmed+DOI
Estévez O, Anibarro L, Garet E, Martínez A, Pena A, Barcia L, Peleteiro M, González-Fernández Á. Multi-parameter flow cytometry immunophenotyping distinguishes different stages of tuberculosis infection. J Infect. 2020;81(1):57–71. PMID: 32330526. DOI: 10.1016/j.jinf.2020.03.064. http://www.ncbi.nlm.nih.gov/pubmed/32330526 +Pubmed+DOI
Estévez O, Anibarro L, Garet E, Pallares Á, Barcia L, Calviño L, Maueia C, Mussá T, Fdez-Riverola F, Glez-Peña D, Reboiro-Jato M, López-Fernández H, Fonseca NA, Reljic R, González-Fernández Á. An RNA-seq Based Machine Learning Approach Identifies Latent Tuberculosis Patients With an Active Tuberculosis Profile. Front Immunol. 2020;11:1470. PMID: 32760401. DOI: 10.3389/fimmu.2020.01470. http://www.ncbi.nlm.nih.gov/pubmed/32760401 +Pubmed+DOI
Estévez O, Anibarro L, Garet E, Pallares Á, Pena A, Villaverde C, Del Campo V, González-Fernández Á. Identification of candidate host serum and saliva biomarkers for a better diagnosis of active and latent tuberculosis infection. PLoS One. 2020;15(7):e0235859. PMID: 32687494. DOI: 10.1371/journal.pone.0235859. http://www.ncbi.nlm.nih.gov/pubmed/32687494 +Pubmed+DOI
González-Fernández Á, Bermúdez Silva FJ, López-Hoyos M, Cobaleda C, Montoliu L, Del Val M, Leech K. Non-animal-derived monoclonal antibodies are not ready to substitute current hybridoma technology. Nat Methods. 2020;17(11):1069–70. PMID: 33020658. DOI: 10.1038/s41592-020-00977-5. http://www.ncbi.nlm.nih.gov/pubmed/33020658 +Pubmed+DOI
Magadán S. Adaptive immune receptor repertoires, an overview of this exciting field. Immunol Lett. 2020;221:49–55. PMID: 32113899. DOI: 10.1016/j.imlet.2020.02.013. http://www.ncbi.nlm.nih.gov/pubmed/32113899 +Pubmed+DOI
Mateos J, Estévez O, González-Fernández Á, Anibarro L, Pallarés Á, Reljic R, Mussá T, Gomes-Maueia C, Nguilichane A, Gallardo JM, Medina I, Carrera M. Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. Sci Rep. 2020 Mar;10(1):3844. PMID: 32123229. DOI: 10.1038/s41598-020-60753-5. http://www.ncbi.nlm.nih.gov/pubmed/32123229 +Pubmed+DOI
Nelissen I, Haase A, Anguissola S, Rocks L, Jacobs A, Willems H, Riebeling C, Luch A, Piret J-P, Toussaint O, Trouiller B, Lacroix G, Gutleb AC, Contal S, Diabaté S, Weiss C, Lozano-Fernández T, González-Fernández Á, Dusinska M, Huk A, Stone V, Kanase N, Nocu? M, St?pnik M, Meschini S, Ammendolia MG, Lewinski N, Riediker M, Venturini M, Benetti F, Topinka J, Brzicova T, Milani S, Rädler J, Salvati A, Dawson KA. Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study. Nanomater (Basel, Switzerland). 2020 Jul;10(8) PMID: 32707981. DOI: 10.3390/nano10081430. http://www.ncbi.nlm.nih.gov/pubmed/32707981 +Pubmed+DOI
Simón-Vázquez R, Peleteiro M, González-Fernández Á. Polymeric nanostructure vaccines: applications and challenges. Expert Opin Drug Deliv. 2020;17(7):1007–23. PMID: 32476491. DOI: 10.1080/17425247.2020.1776259. http://www.ncbi.nlm.nih.gov/pubmed/32476491 +Pubmed+DOI
Torres MD, Flórez-Fernández N, Simón-Vázquez R, Giménez-Abián JF, Díaz JF, González-Fernández Á, Domínguez H. Fucoidans: The importance of processing on their anti-tumoral properties. Algal Res. 2020 Jan;45:101748. DOI: 10.1016/j.algal.2019.101748. https://linkinghub.elsevier.com/retrieve/pii/S2211926419307180 +DOI
Scientific Papers
Batlle R, Andrés E, Gonzalez L, Llonch E, Igea A, Gutierrez-Prat N, Berenguer-Llergo A, Nebreda AR. Regulation of tumor angiogenesis and mesenchymal-endothelial transition by p38? through TGF-? and JNK signaling. Nat Commun. Springer US; 2019;10(1):3071. PMID: 31296856. DOI: 10.1038/s41467-019-10946-y. http://www.ncbi.nlm.nih.gov/pubmed/31296856 +Pubmed+DOI
Carnero-Gregorio M, Molares-Vila A, Corbalán-Rivas A, Villaverde-Taboada C, Rodríguez-Cerdeira C. Effect of VSL#3 Probiotic in a Patient with Glycogen Storage Disease Type Ia and Irritable Bowel Disease-like Disease. Probiotics Antimicrob Proteins. 2019 Feb;11(1):143–9. PMID: 29441457. DOI: 10.1007/s12602-017-9372-9. http://www.ncbi.nlm.nih.gov/pubmed/29441457 +Pubmed+DOI
Carrera M, González-Fernández Á, Magadán S, Mateos J, Pedrós L, Medina I, Gallardo JM. Molecular characterization of B-cell epitopes for the major fish allergen, parvalbumin, by shotgun proteomics, protein-based bioinformatics and IgE-reactive approaches. J Proteomics. 2019 May;200:123–33. PMID: 30974223. DOI: 10.1016/j.jprot.2019.04.005. http://www.ncbi.nlm.nih.gov/pubmed/30974223 +Pubmed+DOI
Crecente-Campo J, Guerra-Varela J, Peleteiro M, Gutiérrez-Lovera C, Fernández-Mariño I, Diéguez-Docampo A, González-Fernández Á, Sánchez L, Alonso MJ. The size and composition of polymeric nanocapsules dictate their interaction with macrophages and biodistribution in zebrafish. J Control Release. 2019;308:98–108. PMID: 31306677. DOI: 10.1016/j.jconrel.2019.07.011. http://www.ncbi.nlm.nih.gov/pubmed/31306677 +Pubmed+DOI
Díaz-Peña R, de Los Santos MJ, Lucia A, Castro-Santos P. Understanding the role of killer cell immunoglobulin-like receptors in pregnancy complications. J Assist Reprod Genet. Journal of Assisted Reproduction and Genetics; 2019 May;36(5):827–35. PMID: 30847698. DOI: 10.1007/s10815-019-01426-9. http://www.ncbi.nlm.nih.gov/pubmed/30847698 +Pubmed+DOI
Faro J, von Haeften B, Gardner R, Faro E. A Sensitivity Analysis Comparison of Three Models for the Dynamics of Germinal Centers. Front Immunol. 2019;10(AUG):2038. PMID: 31543878. DOI: 10.3389/fimmu.2019.02038. http://www.ncbi.nlm.nih.gov/pubmed/31543878 +Pubmed+DOI
González-Ballesteros N, Diego-González L, Lastra-Valdor M, Rodríguez-Argüelles MC, Grimaldi M, Cavazza A, Bigi F, Simón-Vázquez R. Immunostimulant and biocompatible gold and silver nanoparticles synthesized using the Ulva intestinalis L. aqueous extract. J Mater Chem B. 2019;7(30):4677–91. PMID: 31364682. DOI: 10.1039/c9tb00215d. http://www.ncbi.nlm.nih.gov/pubmed/31364682 +Pubmed+DOI
Lorscheider M, Tsapis N, Simón-Vázquez R, Guiblin N, Ghermani N, Reynaud F, Canioni R, Abreu S, Chaminade P, Fattal E. Nanoscale Lipophilic Prodrugs of Dexamethasone with Enhanced Pharmacokinetics. Mol Pharm. 2019;16(7):2999–3010. PMID: 31117740. DOI: 10.1021/acs.molpharmaceut.9b00237. http://www.ncbi.nlm.nih.gov/pubmed/31117740 +Pubmed+DOI
Lozano?Fernández T, Dobrovolskaia M, Camacho T, González?Fernández Á, Simón?Vázquez R. Interference of Metal Oxide Nanoparticles with Coagulation Cascade and Interaction with Blood Components. Part Part Syst Charact. 2019 Apr;36(4):1800547. DOI: 10.1002/ppsc.201800547. https://onlinelibrary.wiley.com/doi/abs/10.1002/ppsc.201800547 +DOI
Magadan S, Jouneau L, Boudinot P, Salinas I. Nasal Vaccination Drives Modifications of Nasal and Systemic Antibody Repertoires in Rainbow Trout. J Immunol. 2019;203(6):1480–92. PMID: 31413108. DOI: 10.4049/jimmunol.1900157. http://www.ncbi.nlm.nih.gov/pubmed/31413108 +Pubmed+DOI
Magadan S, Krasnov A, Hadi-Saljoqi S, Afanasyev S, Mondot S, Lallias D, Castro R, Salinas I, Sunyer O, Hansen J, Koop BF, Lefranc M-P, Boudinot P. Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires. Front Immunol. 2019;10(November):2541. PMID: 31798572. DOI: 10.3389/fimmu.2019.02541. http://www.ncbi.nlm.nih.gov/pubmed/31798572 +Pubmed+DOI
Mateos J, Estévez O, González-Fernández Á, Anibarro L, Pallarés Á, Reljic R, Gallardo JM, Medina I, Carrera M. High-resolution quantitative proteomics applied to the study of the specific protein signature in the sputum and saliva of active tuberculosis patients and their infected and uninfected contacts. J Proteomics. 2019 Mar;195:41–52. PMID: 30660769. DOI: 10.1016/j.jprot.2019.01.010. http://www.ncbi.nlm.nih.gov/pubmed/30660769 +Pubmed+DOI
Navelsaker S, Magadan S, Jouneau L, Quillet E, Olesen NJ, Munang´andu HM, Boudinot P, Evensen Ø. Sequential Immunization With Heterologous Viruses Does Not Result in Attrition of the B Cell Memory in Rainbow Trout. Front Immunol. 2019 Nov;10(November):2687. PMID: 31824488. DOI: 10.3389/fimmu.2019.02687. http://www.ncbi.nlm.nih.gov/pubmed/31824488 +Pubmed+DOI
Olivieri DN, Gambón-Deza F. Iterative Variable Gene Discovery from Whole Genome Sequencing with a Bootstrapped Multiresolution Algorithm. Comput Math Methods Med. 2019 Feb;2019:3780245. PMID: 30886642. DOI: 10.1155/2019/3780245. http://www.ncbi.nlm.nih.gov/pubmed/30886642 +Pubmed+DOI
Reljic R, González-Fernández Á. Editorial: Nanoparticle Vaccines Against Infectious Diseases. Front Immunol. 2019;10(November):2615. PMID: 31787982. DOI: 10.3389/fimmu.2019.02615. http://www.ncbi.nlm.nih.gov/pubmed/31787982 +Pubmed+DOI
Torres Palenzuela JM, González Vilas L, Bellas FM, Garet E, González-Fernández Á, Spyrakos E. Pseudo-nitzschia Blooms in a Coastal Upwelling System: Remote Sensing Detection, Toxicity and Environmental Variables. Water. 2019 Sep;11(9):1954. DOI: 10.3390/w11091954. https://www.mdpi.com/2073-4441/11/9/1954 +DOI
Vieira S, da Silva Morais A, Garet E, Silva-Correia J, Reis RL, González-Fernández Á, Miguel Oliveira J. Self-mineralizing Ca-enriched methacrylated gellan gum beads for bone tissue engineering. Acta Biomater. 2019 Jul;93:74–85. PMID: 30708066. DOI: 10.1016/j.actbio.2019.01.053. http://www.ncbi.nlm.nih.gov/pubmed/30708066 +Pubmed+DOI
Book Chapters
Castro-Santos P, Díaz-Peña R. Pharmacoepigenetics of Rheumatic Disorders. In: Cacabelos R (ed.). Pharmacoepigenetics. Elsevier; 2019. p. 587–96. ISBN: 978-0-12-813940-0. https://linkinghub.elsevier.com/retrieve/pii/B9780128139394000206 +DOI
López OC, Pérez Nieto T, Ferreiro López A, Garet E, González-Fernández Á, Torres Palenzuela JM. Capítulo 8. Análisis de la eficacia de los filtros de arcilla en la retención de contaminación fecal y comparativa de nuevos métodos para la detección de contaminantes. In: Riadigos-García MM, Torres-Palenzuela JM (eds.). BIOAUGA: Red Gallega de Biorremediación y Energía del Agua. Universidade de Vigo – Tórculo; 2019. p. 118–23. Deposito Legal: VG 314-2019. ISBN: 978-84-8158-816-3. https://dialnet.unirioja.es/servlet/articulo?codigo=7470899 Link
Magadán-Mompó S, González-Fernández Á. Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice. In: Steinitz M (ed.). Human Monoclonal Antibodies Methods and Protocols Series: Methods in Molecular Biology (vol1904). New York, NY: Humana Press. Springer New York; 2019. p. 253–91. ISBN: 978-1-4939-8957-7. ISBN: 978-1-4939-8957-7. https://www.springer.com/gp/book/9781493989577 +DOI
Scientific Papers
Anibarro L, Cortés E, Chouza A, Parafita-Fernández A, García JC, Pena A, Fernández-Cid C, González-Fernández Á. Early treatment of tuberculous uveitis improves visual outcome: a 10-year cohort study. Infection. 2018 Aug;46(4):549–54. PMID: 29869018. DOI: 10.1007/s15010-018-1161-1. http://www.ncbi.nlm.nih.gov/pubmed/29869018 +Pubmed+DOI
Crecente-Campo J, Lorenzo-Abalde S, Mora A, Marzoa J, Csaba N, Blanco J, González-Fernández Á, Alonso MJ. Bilayer polymeric nanocapsules: A formulation approach for a thermostable and adjuvanted E. coli antigen vaccine. J Control Release. 2018 Jul;286:20–32. PMID: 30017722. DOI: 10.1016/j.jconrel.2018.07.018. http://www.ncbi.nlm.nih.gov/pubmed/30017722 +Pubmed+DOI
Dávila-Grana Á, Diego-González L, González-Fernández Á, Simón-Vázquez R. Synergistic Effect of Metal Oxide Nanoparticles on Cell Viability and Activation of MAP Kinases and NF?B. Int J Mol Sci. 2018 Jan;19(1):246. PMID: 29342925. DOI: 10.3390/ijms19010246. http://www.ncbi.nlm.nih.gov/pubmed/29342925 +Pubmed+DOI
González-Aramundiz JV, Peleteiro M, González-Fernández Á, Alonso MJ, Csaba NS. Protamine Nanocapsules for the Development of Thermostable Adjuvanted Nanovaccines. Mol Pharm. 2018;15(12):5653–64. PMID: 30375877. DOI: 10.1021/acs.molpharmaceut.8b00852. http://www.ncbi.nlm.nih.gov/pubmed/30375877 +Pubmed+DOI
Labastida-Conde RG, Ramírez-Pliego O, Peleteiro-Olmedo M, Lopez-Guerrero DV, Badillo-Godinez OD, Gutiérrez-Xicoténcatl M de L, Rosas-Salgado G, González-Fernández Á, Esquivel-Guadarrama FR, Santana MA. Flagellin is a Th1 polarizing factor for human CD4+ T cells and induces protection in a murine neonatal vaccination model of rotavirus infection. Vaccine. Elsevier Ltd; 2018 Jul;36(29):4188–97. PMID: 29891347. DOI: 10.1016/j.vaccine.2018.06.005. http://www.ncbi.nlm.nih.gov/pubmed/29891347 +Pubmed+DOI
Peleteiro M, Presas E, González-Aramundiz JV, Sánchez-Correa B, Simón-Vázquez R, Csaba N, Alonso MJ, González-Fernández Á. Polymeric Nanocapsules for Vaccine Delivery: Influence of the Polymeric Shell on the Interaction With the Immune System. Front Immunol. 2018 Apr;9(APR):791. PMID: 29725329. DOI: 10.3389/fimmu.2018.00791. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916973/pdf/fimmu-09-00791.pdf +Pubmed+DOI
Szebeni J, Simberg D, González-Fernández Á, Barenholz Y, Dobrovolskaia MA. Roadmap and strategy for overcoming infusion reactions to nanomedicines. Nat Nanotechnol. 2018;13(12):1100–8. PMID: 30348955. DOI: 10.1038/s41565-018-0273-1. http://www.ncbi.nlm.nih.gov/pubmed/30348955 +Pubmed+DOI
Book Chapters
González-Fernández Á. Capítulo 1. Historia de la Inmunogenética. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf Link
González-Fernández Á. Capítulo 1. Historia de la Inmunogenética. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf Link
González-Fernández Á. Capítulo 1. Historia de la Inmunogenética. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf Link
González-Fernández Á. Capítulo 1. Historia de la Inmunogenética. In: González-Fernández Á (ed.). Inmunogenética. Madrid: EDITORIAL SÍNTESIS, S. A; 2018. p. 19–35. ISBN: 9789004310087. https://www.sintesis.com/data/indices/9788491711551.pdf Link
González-Fernández Á. Capítulo 11. Vacunas. Inmunotecnología y sus aplicaciones. Ediuno. Ediciones de la Universidad de Oviedo; 2018. p. 173–96. ISBN: 978-84-16343-73-7. https://publicaciones.uniovi.es/catalogo/publicaciones/-/asset_publisher/pW5r/content/inmunotecnologia-y-sus-aplicaciones?redirect=%2Fcatalogo%2Fpublicaciones%0A Link
González-Fernández Á. Capítulo 11. Vacunas. Inmunotecnología y sus aplicaciones. Ediuno. Ediciones de la Universidad de Oviedo; 2018. p. 173–96. ISBN: 978-84-16343-73-7. https://publicaciones.uniovi.es/catalogo/publicaciones/-/asset_publisher/pW5r/content/inmunotecnologia-y-sus-aplicaciones?redirect=%2Fcatalogo%2Fpublicaciones%0A Link
González-Fernández Á. Capítulo 17. Historia de los anticuerpos monoclonales. In: Antón A (ed.). Inmunología Tumoral e Inmunoterapia del Cáncer. Amazing Books; 2018. ISBN: 978-84-17403-15-7. https://amazingbooks.es/inmunologia-tumoral-e-inmunoterapia-del-cancer%0A Link
Scientific Papers
Faro J, Castro M, Molina-París C. A unifying mathematical framework for experimental TCR-pMHC kinetic constants. Sci Rep. Nature Publishing Group; 2017 Apr;7:46741. PMID: 28443634. DOI: 10.1038/srep46741. IF2017: 4.122; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28443634 +Pubmed+DOI
Fernandez-Carrera A, Vigo E, Regueiro-Rodríguez C, González-Fernández Á, Olivieri D, Aroeira LS. Sensitive and non-invasive method for the in vivo analysis of membrane permeability in small animals. Lab Invest. 2017 Sep;97(9):1114–20. PMID: 28737767. DOI: 10.1038/labinvest.2017.66. IF2017: 4.254; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28737767 +Pubmed+DOI
Gomez-Tourino I, Kamra Y, Baptista R, Lorenc A, Peakman M. T cell receptor ?-chains display abnormal shortening and repertoire sharing in type 1 diabetes. Nat Commun. Springer US; 2017;8(1):1792. PMID: 29176645. DOI: 10.1038/s41467-017-01925-2. http://dx.doi.org/10.1038/s41467-017-01925-2 +Pubmed+DOI
Hidalgo T, Cooper L, Gorman M, Lozano-Fernández T, Simón-Vázquez R, Mouchaham G, Marrot J, Guillou N, Serre C, Fertey P, González-Fernández Á, Devic T, Horcajada P. Crystal structure dependent in vitro antioxidant activity of biocompatible calcium gallate MOFs. J Mater Chem B. 2017 Apr;5(15):2813–22. DOI: 10.1039/C6TB03101C. IF2017: 4.776; Q1. http://xlink.rsc.org/?DOI=C6TB03101C +DOI
Hidalgo T, Giménez-Marqués M, Bellido E, Avila J, Asensio MC, Salles F, Lozano M V, Guillevic M, Simón-Vázquez R, González-Fernández A, Serre C, Alonso MJ, Horcajada P. Chitosan-coated mesoporous MIL-100(Fe) nanoparticles as improved bio-compatible oral nanocarriers. Sci Rep. 2017 Mar;7:43099. PMID: 28256600. DOI: 10.1038/srep43099. IF2017: 4.122; Q1. http://www.ncbi.nlm.nih.gov/pubmed/28256600 +Pubmed+DOI
Maceiras AR, Almeida SCP, Mariotti-Ferrandiz E, Chaara W, Jebbawi F, Six A, Hori S, Klatzmann D, Faro J, Graca L. T follicular helper and T follicular regulatory cells have different TCR specificity. Nat Commun. Nature Publishing Group; 2017 Apr;8:15067. PMID: 28429709. DOI: 10.1038/ncomms15067. IF2017: 12.353; D1. http://www.ncbi.nlm.nih.gov/pubmed/28429709 +Pubmed+DOI
Ruhwald M, Aggerbeck H, Gallardo RV, Hoff ST, Villate JI, Borregaard B, Martinez JA, Kromann I, Penas A, Anibarro LL, de Souza-Galvão ML, Sánchez F, Rodrigo-Pendás JÁ, Noguera-Julian A, Martínez-Lacasa X, Tuñez MV, Fernández VL, Millet JP, Moreno A, Cobos N, Miró JM, Roldan L, Orcau A, Andersen P, Caylá JA, TESEC Working Group. Safety and efficacy of the C-Tb skin test to diagnose Mycobacterium tuberculosis infection, compared with an interferon ? release assay and the tuberculin skin test: a phase 3, double-blind, randomised, controlled trial. Lancet Respir Med. 2017 Apr;5(4):259–68. PMID: 28159608. DOI: 10.1016/S2213-2600(16)30436-2. IF2017: 21.466; D1. http://www.ncbi.nlm.nih.gov/pubmed/28159608 +Pubmed+DOI
Scientific Papers
Calvo-Iglesias J, Pérez-Estévez D, Lorenzo-Abalde S, Sánchez-Correa B, Quiroga MI, Fuentes JM, González-Fernández Á. Characterization of a Monoclonal Antibody Directed against Mytilus spp Larvae Reveals an Antigen Involved in Shell Biomineralization. PLoS One. 2016 Mar;11(3):e0152210. PMID: 27008638. DOI: 10.1371/journal.pone.0152210. IF2016: 2.806; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27008638 +Pubmed+DOI
Estevez O, Garet E, Olivieri D, Gambón-Deza F. Amphibians have immunoglobulins similar to ancestral IgD and IgA from Amniotes. Mol Immunol. 2016 Jan;69:52–61. PMID: 26675067. DOI: 10.1016/j.molimm.2015.11.005. FI2016: 3.236; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26675067 +Pubmed+DOI
García-García J-M, Rodrigo T, Casals M, Ruiz-Manzano J, Pascual-Pascual T, Caylà JA, Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis-PIITB (Luis Anibarro). Spanish Compliance With Guidelines for Prescribing Four Drugs in the Intensive Phase of Standard Tuberculosis Treatment. Arch Bronconeumol. 2016 May;52(5):262–8. PMID: 26826890. DOI: 10.1016/j.arbres.2015.11.007. IF2016: 2.979; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26826890 +Pubmed+DOI
Gullón JA, García-García JM, Villanueva MÁ, Álvarez-Navascues F, Rodrigo T, Casals M, Anibarro L, García-Clemente MM, Jiménez MÁ, Bustamante A, Penas A, Caminero JA, Caylà J, Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis (PII TB). Tuberculosis Costs in Spain and Related Factors. Arch Bronconeumol. 2016 Dec;52(12):583–9. PMID: 27323653. DOI: 10.1016/j.arbres.2016.05.002. IF2016: 2.979; Q2. http://www.ncbi.nlm.nih.gov/pubmed/27323653 +Pubmed+DOI
Martins JT, Santos SF, Bourbon AI, Pinheiro AC, González-Fernández Á, Pastrana LM, Cerqueira MA, Vicente AA. Lactoferrin-based nanoparticles as a vehicle for iron in food applications – Development and release profile. Food Res Int. 2016 Dec;90:16–24. PMID: 29195869. DOI: 10.1016/j.foodres.2016.10.027. IF2016: 3.086; Q1. http://www.ncbi.nlm.nih.gov/pubmed/29195869 +Pubmed+DOI
Olivieri DN, Garet E, Estevez O, Sánchez-Espinel C, Gambón-Deza F. Genomic structure and expression of immunoglobulins in Squamata. Mol Immunol. 2016 Apr;72:81–91. PMID: 26998711. DOI: 10.1016/j.molimm.2016.03.003. IF2016: 3.236; Q2. http://www.ncbi.nlm.nih.gov/pubmed/26998711 +Pubmed+DOI
Rodrigo T, Casals M, Caminero JA, García-García JM, Jiménez-Fuentes MA, Medina JF, Millet JP, Ruiz-Manzano J, Caylá J, Working Group of the Integrated Programme of Tuberculosis Research. Factors Associated with Fatality during the Intensive Phase of Anti-Tuberculosis Treatment. Chotirmall SH (ed.). PLoS One. 2016 Aug;11(8):e0159925. PMID: 27487189. DOI: 10.1371/journal.pone.0159925. IF2016: 2.806; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27487189 +Pubmed+DOI
Santin M, García-García J-M, Domínguez J, Panel of experts from the Mycobacteria Study Group (GEIM) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Respiratory Diseases and Thoracic Surgery (SEPAR). Guidelines for the use of interferon-? release assays in the diagnosis of tuberculosis infection. Enferm Infecc Microbiol Clin. 2016 May;34(5):303.e1-13. PMID: 26917222. DOI: 10.1016/j.eimc.2015.11.022. IF2016: 1.714; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26917222 +Pubmed+DOI
Santin M, Garcia-Garcia J-M, Rigau D, Altet N, Anibarro L, Casas I, Diez N, Garcia-Gasalla M, Martinez-Lacasa X, Penas AA, Perez-Escolano E, Sanchez F, Dominguez J, García-García J-M, Rigau D, Altet N, Anibarro L, Casas I, Díez N, García-Gasalla M, Martínez-Lacasa X, Penas AA, Pérez-Escolano E, Sánchez F, Domínguez J, Grupo de expertos del Grupo de Estudio de Micobacterias (GEIM) de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y la Sociedad Española de Enfermedades Respiratorias y Cirugía torácica (SEPAR), Panel of experts from the Mycobacteria Study Group (GEIM) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Respiratory Diseases and Thoracic Surgery (SEPAR). Executive summary of the guidelines for the use of interferon-gamma release assays in the diagnosis of tuberculosis infection. Enferm Infecc Microbiol Clin. 2016 May;34(5):304–8. PMID: 26926262. DOI: 10.1016/j.eimc.2015.11.021. IF2016: 1.714; Q3. http://www. +Pubmed+DOI
Simón-Vázquez R, Lozano-Fernández T, Dávila-Grana A, González-Fernández Á. Analysis of the activation routes induced by different metal oxide nanoparticles on human lung epithelial cells. Futur Sci OA. 2016 Jun;2(2):fso.16.2. PMID: 28031965. DOI: 10.4155/fso.16.2. IF2016: N/A. http://www.ncbi.nlm.nih.gov/pubmed/28031965 +Pubmed+DOI
Simón-Vázquez R, Lozano-Fernández T, Dávila-Grana A, González-Fernández A. Metal oxide nanoparticles interact with immune cells and activate different cellular responses. Int J Nanomedicine. 2016;11:4657–68. PMID: 27695324. DOI: 10.2147/IJN.S110465. IF2016: 4.300; Q1. http://www.ncbi.nlm.nih.gov/pubmed/27695324 +Pubmed+DOI
Book Chapters
França Á, Pelaz B, Moros M, Sánchez-Espinel C, Hernández A, Fernández-López C, Grazú V, Fuente JM de la, Pastoriza-Santos I, González-Fernández Á. Chapter 4: Sterilization Case Study 1: Effects of Different Sterilization Techniques on Gold Nanoparticles. In: Dobrovolskaia MA, McNeil SE (eds.). Handbook of Immunological Properties of Engineered Nanomaterials Volume 1: Key Considerations for Nanoparticle Characterization Prior to Immunotoxicity Studies. 2nd ed. World Scientific; 2016. p. 77–92. ISBN: 978-981-3140-43-1. http://www.worldscientific.com/doi/abs/10.1142/9789813140431_0004 +DOI
Lorenzo-Abalde S, González-Fernández Á. Chapter 10: Nanostructures and Allergy. In: Dobrovolskaia MA, McNeil SE (eds.). Handbook of Immunological Properties of Engineered Nanomaterials Volume 1: Key Considerations for Nanoparticle Characterization Prior to Immunotoxicity Studies. 2nd ed. World Scientific; 2016. p. 241–69. ISBN: 978-981-3140-43-1. http://www.worldscientific.com/doi/abs/10.1142/9789813140479_0010 +DOI
Lorenzo-Abalde S, Simón-Vázquez R, Olmedo MP, Lozano-Fernández T, Estévez-Martínez O, Fernández-Carrera A, González-Fernández Á. Evaluating the Interactions Between Proteins and Components of the Immune System with Polymer Nanoparticles. In: Vauthier C, Ponchel G (eds.). Polymer Nanoparticles for Nanomedicines A Guide for their Design, Preparation and Development. Cham: Springer International Publishing; 2016. p. 221–90. ISBN: 978-3-319-41419-5. https://rd.springer.com/content/pdf/bfm%3A978-3-319-41421-8%2F1.pdf +DOI
Scientific Papers
Bellido E, Hidalgo T, Lozano MV, Guillevic M, Simón-Vázquez R, Santander-Ortega MJ, González-Fernández Á, Serre C, Alonso MJ, Horcajada P. Heparin-engineered mesoporous iron metal-organic framework nanoparticles: toward stealth drug nanocarriers. Adv Healthc Mater. 2015 Jun;4(8):1246–57. PMID: 25771896. DOI: 10.1002/adhm.201400755. IF2015: 5.760; D1. http://www.ncbi.nlm.nih.gov/pubmed/25771896 +Pubmed+DOI
Canoa P, Simón-Vázquez R, Popplewell J, González-Fernández Á. A quantitative binding study of fibrinogen and human serum albumin to metal oxide nanoparticles by surface plasmon resonance. Biosens Bioelectron. Elsevier; 2015 Dec;74:376–83. PMID: 26162328. DOI: 10.1016/j.bios.2015.05.070. IF2015: 7.476; D1. http://www.ncbi.nlm.nih.gov/pubmed/26162328 +Pubmed+DOI
Cooper L, Hidalgo T, Gorman M, Lozano-Fernández T, Simón-Vázquez R, Olivier C, Guillou N, Serre C, Martineau C, Taulelle F, Damasceno-Borges D, Maurin G, González-Fernández Á, Horcajada P, Devic T. A biocompatible porous Mg-gallate metal-organic framework as an antioxidant carrier. Chem Commun (Camb). 2015 Apr;51(27):5848–51. PMID: 25720815. DOI: 10.1039/c5cc00745c. IF2015: 6.567; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25720815 +Pubmed+DOI
Correia A, Ferreirinha P, Botelho S, Belinha A, Leitão C, Caramalho Í, Teixeira L, González-Fernandéz Á, Appelberg R, Vilanova M. Predominant role of interferon-? in the host protective effect of CD8(+) T cells against Neospora caninum infection. Sci Rep. 2015 Oct;5:14913. PMID: 26449650. DOI: 10.1038/srep14913. IF2015: 5.228; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26449650 +Pubmed+DOI
Correia-Pinto JF, Peleteiro M, Csaba N, González-Fernández Á, Alonso MJ. Multi-enveloping of particulated antigens with biopolymers and immunostimulant polynucleotides. J Drug Deliv Sci Technol. 2015 Dec;30:424–34. DOI: 10.1016/j.jddst.2015.08.010. IF2015: 0.620; Q4. http://linkinghub.elsevier.com/retrieve/pii/S1773224715300095 +DOI
de Souza LR, Muehlmann LA, Matos LC, Simón-Vázquez R, Lacava ZGM, De-Paula AMB, Mosiniewicz-Szablewska E, Suchocki P, Morais PC, González-Fernández Á, Báo SN, Azevedo RB. Antitumor activity and systemic effects of PVM/MA-shelled selol nanocapsules in lung adenocarcinoma-bearing mice. Nanotechnology. 2015 Dec;26(50):505101. PMID: 26580675. DOI: 10.1088/0957-4484/26/50/505101. IF2015: 3.573; Q1. http://stacks.iop.org/0957-4484/26/i=50/a=505101?key=crossref.50288d41c986c430342c79d022041ca8 +Pubmed+DOI
Gómez-Touriño I, Simón-Vázquez R, Alonso-Lorenzo J, Arif S, Calviño-Sampedro C, González-Fernández Á, Pena-González E, Rodríguez J, Viñuela-Roldán J, Verdaguer J, Cordero OJ, Peakman M, Varela-Calvino R. Characterization of the autoimmune response against the nerve tissue S100? in patients with type 1 diabetes. Clin Exp Immunol. 2015 May;180(2):207–17. PMID: 25516468. DOI: 10.1111/cei.12572. IF2015: 3.148; Q2. http://www.ncbi.nlm.nih.gov/pubmed/25516468 +Pubmed+DOI
González-Aramundiz JV, Peleteiro-Olmedo M, González-Fernández Á, Alonso Fernández MJ, Csaba NS. Protamine-based nanoparticles as new antigen delivery systems. Eur J Pharm Biopharm. 2015 Nov;97(Pt A):51–9. PMID: 26455338. DOI: 10.1016/j.ejpb.2015.09.019. IF2015: 3.975; Q1. http://www.ncbi.nlm.nih.gov/pubmed/26455338 +Pubmed+DOI
Oliveira ACN, Raemdonck K, Martens T, Rombouts K, Simón-Vázquez R, Botelho C, Lopes I, Lúcio M, González-Fernández Á, Real Oliveira MECD, Gomes AC, Braeckmans K. Stealth monoolein-based nanocarriers for delivery of siRNA to cancer cells. Acta Biomater. 2015 Oct;25:216–29. PMID: 26225736. DOI: 10.1016/j.actbio.2015.07.032. IF2015: 6.008; D1. http://www.ncbi.nlm.nih.gov/pubmed/26225736 +Pubmed+DOI
Olivieri DN, Gambón-Cerdá S, Gambón-Deza F. Evolution of V genes from the TRV loci of mammals. Immunogenetics. 2015 Jul;67(7):371–84. PMID: 26024913. DOI: 10.1007/s00251-015-0850-5. IF2015: 2.303; Q3. http://www.ncbi.nlm.nih.gov/pubmed/26024913 +Pubmed+DOI
Olivieri DN, Gambón-Deza F. V genes in primates from whole genome sequencing data. Immunogenetics. 2015 Apr;67(4):211–28. PMID: 25721877. DOI: 10.1007/s00251-015-0830-9. IF2015: 2.303; Q3. http://www.ncbi.nlm.nih.gov/pubmed/25721877 +Pubmed+DOI
Pereira P, Pedrosa SS, Correia A, Lima CF, Peleteiro-Olmedo M, González-Fernández Á, Vilanova M, Gama FM. Biocompatibility of a self-assembled glycol chitosan nanogel. Toxicol In Vitro. 2015 Apr;29(3):638–46. PMID: 25482991. DOI: 10.1016/j.tiv.2014.11.004. IF2015: 3.338; Q1. http://www.ncbi.nlm.nih.gov/pubmed/25482991 +Pubmed+DOI
Posada García C, Pena A, Anibarro L, Pardavila RM, De La Torre C, González-Fernández A. Erythema induratum of Bazin induced by tuberculin skin test. Int J Dermatol. 2015 Nov;54(11):1297–9. PMID: 24320214. DOI: 10.1111/ijd.12363. IF2015: 1.415; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24320214 +Pubmed+DOI
Sousa-Herves A, Sánchez Espinel C, Fahmi A, González-Fernández Á, Fernandez-Megia E. In situ nanofabrication of hybrid PEG-dendritic-inorganic nanoparticles and preliminary evaluation of their biocompatibility. Nanoscale. 2015 Mar;7(9):3933–40. PMID: 25530028. DOI: 10.1039/c4nr06155a. IF2015: 7.760; D1. http://www.ncbi.nlm.nih.gov/pubmed/25530028 +Pubmed+DOI
Scientific Papers
Anibarro L, Pena A. Tuberculosis in patients with haematological malignancies. Mediterr J Hematol Infect Dis. 2014 Jan;6(1):e2014026. PMID: 24803999. DOI: 10.4084/MJHID.2014.026. N/A; N/A. http://www.ncbi.nlm.nih.gov/pubmed/24803999 +Pubmed+DOI
Cruz-Ferro E, Ursúa-Díaz MI, Taboada-Rodríguez JA, Hervada-Vidal X, Anibarro L, Túñez V, Galician Tuberculosis Prevention and Control Programme Working Group. In reply (Effect of smear-negative pulmonary tuberculosis on transmission). Int J Tuberc Lung Dis. 2014 Jun;18(6):752–3. PMID: 24903951. DOI: 10.5588/ijtld.14.0084-2. IF: 2.315; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24903951 +Pubmed+DOI
Cruz-Ferro E, Ursúa-Díaz MI, Taboada-Rodríguez JA, Hervada-Vidal X, Anibarro L, Túñez V. Epidemiology of tuberculosis in Galicia, Spain, 16 years after the launch of the Galician tuberculosis programme. Int J Tuberc Lung Dis. 2014 Feb;18(2):134–40. PMID: 24429303. DOI: 10.5588/ijtld.13.0419. IF: 2.315; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24429303 +Pubmed+DOI
Llop J, Estrela-Lopis I, Ziolo RF, González A, Fleddermann J, Dorn M, Vallejo VG, Simon-Vazquez R, Donath E, Mao Z, Gao C, Moya SE. Uptake, Biological Fate, and Toxicity of Metal Oxide Nanoparticles. Part Part Syst Charact. WILEY-V C H VERLAG GMBH; 2014 Jan;31(1):24–35. DOI: 10.1002/ppsc.201300323. IF: 3.081; Q1. http://doi.wiley.com/10.1002/ppsc.201300323 +DOI
Lozano-Fernández T, Ballester-Antxordoki L, Pérez-Temprano N, Rojas E, Sanz D, Iglesias-Gaspar M, Moya S, González-Fernández Á, Rey M. Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4. Nanomedicine. 2014 Aug;10(6):1301–10. PMID: 24650882. DOI: 10.1016/j.nano.2014.03.007. IF: 6.155; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24650882 +Pubmed+DOI
Nuñez Fernández MJ, Fachal Bermúdez C, Duran Muñoz D, Figueroa López RM, Sopeña Pérez-Argüelles B, García García JC, Anibarro García L. IgG4-related disease and isolated thoracic aortic aneurysm. Vasa. 2014 Sep;43(5):385–9. PMID: 25147016. DOI: 10.1024/0301-1526/a000375. IF: 1.000; Q4. http://www.ncbi.nlm.nih.gov/pubmed/25147016 +Pubmed+DOI
Olivieri DN, von Haeften B, Sánchez-Espinel C, Faro J, Gambón-Deza F. Genomic V exons from whole genome shotgun data in reptiles. Immunogenetics. 2014 Aug;66(7–8):479–92. PMID: 24893587. DOI: 10.1007/s00251-014-0784-3. IF: 2.227; Q3. http://www.ncbi.nlm.nih.gov/pubmed/24893587 +Pubmed+DOI
Simón-Vázquez R, Lozano-Fernández T, Peleteiro-Olmedo M, González-Fernández Á. Conformational changes in human plasma proteins induced by metal oxide nanoparticles. Colloids Surf B Biointerfaces. 2014 Jan;113:198–206. PMID: 24095988. DOI: 10.1016/j.colsurfb.2013.08.047. IF: 4.152; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24095988 +Pubmed+DOI
Vicente S, Peleteiro M, Gonzalez-Aramundiz J V, Díaz-Freitas B, Martínez-Pulgarín S, Neissa JI, Escribano JM, Sanchez A, González-Fernández A, Alonso MJ. Highly versatile immunostimulating nanocapsules for specific immune potentiation. Nanomedicine (Lond). 2014 Oct;9(15):2273–89. PMID: 24673264. DOI: 10.2217/nnm.14.10. IF: 5.413; Q1. http://www.ncbi.nlm.nih.gov/pubmed/24673264 +Pubmed+DOI
Book Chapters
de Carlos Villamarín A, Faro Rivas JM, González-Fernández Á, Martínez-Zorzano VS, Megías-Pacheco M, Molist-García P, Morán-Martínez P, Pasantes-Ludeña JJ, Pombal Diego MÁ, Quesada-Rodríguez H. Manual de técnicas experimentais en bioloxía molecular e celular – Servizo de Publicacións – Universidade de Vigo. Faro Rivas JM (ed.). 1st ed. Vigo: Banda verde – Manuais; 2014. ISBN: 9788481586749. http://publicacions.uvigo.es/publicacions_gl/contenido/publicacions/publicacion_0326.html?__locale=en Link
Mompó SM, González-Fernández Á. Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice. In: Steinitz M (ed.). Human Monoclonal Antibodies: Methods and Protocols (Colección: Methods in Molecular Biology). Totowa, NJ (USA): Humana Press; 2014. p. 245–76. http://www.ncbi.nlm.nih.gov/pubmed/24037845 +Pubmed+DOI
Code
ED431C 2020/02
Title
Inmunoloxía
Funder
Consellería de Cultura, Educación e Ordenación Universitaria
Type
Individual
Duration
2020 – 2023
PI
África González Fernández
Code
BIO2017-84974-R
Title
Inmunoterapia en cáncer de páncreas: vacunación frente a K-RAS mutado
Funder
Ministerio de Economía y Competitividad
Type
Individual
Duration
2018 – 2021
PI
África González Fernández
Cols.
A. Martínez. E. de Miguel. L. Diego. R. Simón
Code
0181_NANOEATERS_1_E
Title
Transferencia y valorización de nanotecnologías a PYMES innovadoras (early adopters) de la Eurorregión
Funder
Comisión Europea
Type
Multicéntrico
Duration
2017 – 2021
PI
África González Fernández
Coordinator
Institucional (Coord. Axencia Galega de Innovación)
Code
ED431G/02
Title
Centros Singulares: Centro de Investigación Biomédica (CINBIO)
Funder
Consellería de Cultura, Educación e Ordenación Universitaria
Type
Coordinado
Duration
2016 – 2019
PI
África González Fernández
Code
ED431C 2016-041
Title
Grupos de Referencia Competitiva 2016
Funder
Consellería de Cultura, Educación e Ordenación Universitaria
Type
Individual
Duration
2016 – 2019
PI
África González Fernández
Code
643558
Title
Eliciting Mucosal Immunity to Tuberculosis (EMI-TB)
Funder
Comisión Europea
Type
Coordinado
Duration
2015 – 2019
PI
África González Fernández
Coordinator
Dr Rajko Reljic (Coord. St George´s, University of London, UK)
Code
BIO2014-53091-C3-1-R
Title
Diseño de nanovacunas terapéuticas basadas en péptidos. Aplicación al tratamiento de enfermedades autoinmunes
Funder
Ministerio de Economía y Competitividad
Type
Coordinado
Duration
2015 – 2018
PI
África González Fernández
Code
PIRSES-GA-2012-317893
Title
Indo-European Network in Mathematics for Health and Disease
Funder
Comisión Europea
Type
Coordinado
Duration
2013 – 2017
PI
Jose Manuel Faro Rivas
Code
GPC2013/005
Title
Grupos con potencial de crecemento
Funder
Consellería de Cultura, Educación e Ordenación Universitaria
Type
Individual
Duration
2013 – 2015
PI
África González Fernández
Code
FP7-316265-BIOCAPS
Title
Biomedical Capacities Support Program
Funder
Comisión Europea
Type
Multicéntrico
Duration
2013 – 2016
PI
África González Fernández
Code
SAF2011-30337-C02-02
Title
Estudio de la interacción de nanomateriales con antígenos: una aproximación sistemática para el desarrollo de nanovacunas
Funder
Ministerio de Economía y Competitividad
Type
Coordinado
Duration
2012 – 2014
PI
África González Fernández
Coordinator
María José Alonso (Coord. Universidad de Santiago de Compostela)
Code
CN 2012/273 / INB1
Title
Contribución a un mellor coñecemento das patoloxías dende unha perspectiva multidisciplinar – Agrupación Estratégica para la Investigación en Biomedicina – INBIOMEDINBIOMED
Funder
Consellería de Cultura, Educación e Ordenación Universitaria
Type
Coordinado
Duration
2012 – 2015
PI
África González Fernández
Coordinator
Angel Rodríguez de Lera (Coord. Universidad de Vigo)
Code
INS-415
PI
Luis Anibarro García
Title
ARI–E – Estudio multicéntrico, aleatorizado, doble ciego, controlado con placebo y con tratamiento activo para validar los instrumentos de medida de resultados notificados por el paciente, en pacientes adultos, con infección pulmonar por micobacterias no tuberculosas (MNT) de nuevo diagnostico causada por el complejo Mycobacterium avium (MAC)
Start date
2021
Sponsor
Insmed Incorporated
Code
INS-416
PI
Luis Anibarro García
Title
Estudio multicéntrico, aleatorizado, doble ciego, controlado con placebo y con tratamiento activo para evaluar la eficacia y seguridad de un régimen basado en la suspensión para inhalación de liposomas de amikacina (ALIS) en pacientes adultos con infección pulmonar por micobacterias no tuberculosas (MNT) de nuevo diagnostico causada por el complejo Mycobacterium avium (MAC)
Start date
2021
Sponsor
Insmed Incorporated
Code
TESEC-06
PI
Luis Anibarro García
Title
Ensayo de fase III de seguimiento de contactos comparando el funcionamiento diagnóstico de C-Tb frente a ?QuantiFERON®-TBC Gold In-Tube?. en combinación con un análisis de seguridad aleatorizado y doble ciego en diferentes partes del cuerpo de C-Tb frente a 2 UT de Tuberculina PPD RT23SSI (PPD)
Start date
2012
Sponsor
Statens Serum Institute
Title
Candidate immunological and transcriptional biomarkers for the different stages of Tuberculosis infection
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